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Volumn 7, Issue 10, 2012, Pages

Forkhead Transcription Factor FOXP3 Upregulates CD25 Expression through Cooperation with RelA/NF-κB

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELA;

EID: 84868087600     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048303     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor foxp3
    • Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, et al. (2005) Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 22: 329-341.
    • (2005) Immunity , vol.22 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3    Dooley, J.L.4    Farr, A.G.5
  • 2
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • Shevach EM, (2009) Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 30: 636-645.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 3
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: of mice and men
    • Ziegler SF, (2006) FOXP3: of mice and men. Annu Rev Immunol 24: 209-226.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 4
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, et al. (2001) The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 27: 20-21.
    • (2001) Nat Genet , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3    Brunkow, M.E.4    Ferguson, P.J.5
  • 5
    • 0038434099 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
    • Gambineri E, Torgerson TR, Ochs HD, (2003) Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 15: 430-435.
    • (2003) Curr Opin Rheumatol , vol.15 , pp. 430-435
    • Gambineri, E.1    Torgerson, T.R.2    Ochs, H.D.3
  • 6
    • 33747762947 scopus 로고    scopus 로고
    • Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor
    • Lopes JE, Torgerson TR, Schubert LA, Anover SD, Ocheltree EL, et al. (2006) Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor. J Immunol 177: 3133-3142.
    • (2006) J Immunol , vol.177 , pp. 3133-3142
    • Lopes, J.E.1    Torgerson, T.R.2    Schubert, L.A.3    Anover, S.D.4    Ocheltree, E.L.5
  • 7
    • 79954675867 scopus 로고    scopus 로고
    • Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells
    • Bandukwala HS, Wu Y, Feuerer M, Chen Y, Barboza B, et al. (2011) Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity 34: 479-491.
    • (2011) Immunity , vol.34 , pp. 479-491
    • Bandukwala, H.S.1    Wu, Y.2    Feuerer, M.3    Chen, Y.4    Barboza, B.5
  • 8
    • 33846016948 scopus 로고    scopus 로고
    • Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation
    • Chen C, Rowell EA, Thomas RM, Hancock WW, Wells AD, (2006) Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation. J Biol Chem 281: 36828-36834.
    • (2006) J Biol Chem , vol.281 , pp. 36828-36834
    • Chen, C.1    Rowell, E.A.2    Thomas, R.M.3    Hancock, W.W.4    Wells, A.D.5
  • 9
    • 33746228122 scopus 로고    scopus 로고
    • FOXP3 controls regulatory T cell function through cooperation with NFAT
    • Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, et al. (2006) FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126: 375-387.
    • (2006) Cell , vol.126 , pp. 375-387
    • Wu, Y.1    Borde, M.2    Heissmeyer, V.3    Feuerer, M.4    Lapan, A.D.5
  • 10
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli E, Dastrange M, Oukka M, (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 102: 5138-5143.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 11
    • 34247215187 scopus 로고    scopus 로고
    • Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
    • Ono M, Yaguchi H, Ohkura N, Kitabayashi I, Nagamura Y, et al. (2007) Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature 446: 685-689.
    • (2007) Nature , vol.446 , pp. 685-689
    • Ono, M.1    Yaguchi, H.2    Ohkura, N.3    Kitabayashi, I.4    Nagamura, Y.5
  • 12
    • 34248379172 scopus 로고    scopus 로고
    • FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression
    • Li B, Samanta A, Song X, Iacono KT, Bembas K, et al. (2007) FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci U S A 104: 4571-4576.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4571-4576
    • Li, B.1    Samanta, A.2    Song, X.3    Iacono, K.T.4    Bembas, K.5
  • 13
    • 52949138267 scopus 로고    scopus 로고
    • TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3
    • Samanta A, Li B, Song X, Bembas K, Zhang G, et al. (2008) TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci U S A 105: 14023-14027.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14023-14027
    • Samanta, A.1    Li, B.2    Song, X.3    Bembas, K.4    Zhang, G.5
  • 14
    • 77649225958 scopus 로고    scopus 로고
    • Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
    • van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, et al. (2010) Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. Blood 115: 965-974.
    • (2010) Blood , vol.115 , pp. 965-974
    • van Loosdregt, J.1    Vercoulen, Y.2    Guichelaar, T.3    Gent, Y.Y.4    Beekman, J.M.5
  • 15
    • 0029150110 scopus 로고
    • Immunologic self tolerance maintained by activated T cells expressing IL-2 receptor alphachains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M, (1995) Immunologic self tolerance maintained by activated T cells expressing IL-2 receptor alphachains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155: 1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 16
    • 33750219508 scopus 로고    scopus 로고
    • Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
    • Kim HP, Imbert J, Leonard WJ, (2006) Both integrated and differential regulation of components of the IL-2/IL-2 receptor system. Cytokine Growth Factor Rev 17: 349-366.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 349-366
    • Kim, H.P.1    Imbert, J.2    Leonard, W.J.3
  • 17
    • 0028892099 scopus 로고
    • In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells
    • Algarte M, Lecine P, Costello R, Plet A, Olive D, et al. (1995) In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells. Embo J 14: 5060-5072.
    • (1995) Embo J , vol.14 , pp. 5060-5072
    • Algarte, M.1    Lecine, P.2    Costello, R.3    Plet, A.4    Olive, D.5
  • 18
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY, (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 19
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S, (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 20
    • 0036679733 scopus 로고    scopus 로고
    • It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation
    • Kane LP, Lin J, Weiss A, (2002) It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends Immunol 23: 413-420.
    • (2002) Trends Immunol , vol.23 , pp. 413-420
    • Kane, L.P.1    Lin, J.2    Weiss, A.3
  • 21
    • 49049107205 scopus 로고    scopus 로고
    • FOXP3 induced by CD28/B7 interaction regulates CD25 and anergic phenotype in human CD4+CD25- T lymphocytes
    • Scotta C, Soligo M, Camperio C, Piccolella E, (2008) FOXP3 induced by CD28/B7 interaction regulates CD25 and anergic phenotype in human CD4+CD25- T lymphocytes. J Immunol 181: 1025-1033.
    • (2008) J Immunol , vol.181 , pp. 1025-1033
    • Scotta, C.1    Soligo, M.2    Camperio, C.3    Piccolella, E.4
  • 22
    • 78851469262 scopus 로고    scopus 로고
    • CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism
    • Soligo M, Camperio C, Caristi S, Scotta C, Del Porto P, et al. (2011) CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism. Eur J Immunol 41: 503-513.
    • (2011) Eur J Immunol , vol.41 , pp. 503-513
    • Soligo, M.1    Camperio, C.2    Caristi, S.3    Scotta, C.4    Del Porto, P.5
  • 23
    • 0017710978 scopus 로고
    • Characteristics of a human cell line trasformed by DNA from human adenovirus type 5
    • Graham FL, Smiley J, Russell WC, Nairn R, (1977) Characteristics of a human cell line trasformed by DNA from human adenovirus type 5. J Gen Virol 36: 59-74.
    • (1977) J Gen Virol , vol.36 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 24
    • 0017702412 scopus 로고
    • Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
    • Schneider U, Schwenk H, Bornkamm G, (1977) Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int J Cancer 19: 621-626.
    • (1977) Int J Cancer , vol.19 , pp. 621-626
    • Schneider, U.1    Schwenk, H.2    Bornkamm, G.3
  • 25
    • 0033829852 scopus 로고    scopus 로고
    • Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-κB activation
    • Tuosto L, Costanzo A, Guido F, Marinari B, Vossio S, et al. (2000) Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-κB activation. Eur J Immunol 30: 2445-2454.
    • (2000) Eur J Immunol , vol.30 , pp. 2445-2454
    • Tuosto, L.1    Costanzo, A.2    Guido, F.3    Marinari, B.4    Vossio, S.5
  • 26
    • 77953973423 scopus 로고    scopus 로고
    • Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3
    • Koh KP, Sundrud MS, Rao A, (2009) Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3. PLoS One 4: e8109.
    • (2009) PLoS One , vol.4
    • Koh, K.P.1    Sundrud, M.S.2    Rao, A.3
  • 27
    • 17044410174 scopus 로고    scopus 로고
    • Signals from CD28 induce stable epigenetic modification of the IL-2 promoter
    • Thomas RM, Gao L, Wells AD, (2005) Signals from CD28 induce stable epigenetic modification of the IL-2 promoter. J Immunol 174: 4639-4646.
    • (2005) J Immunol , vol.174 , pp. 4639-4646
    • Thomas, R.M.1    Gao, L.2    Wells, A.D.3
  • 28
    • 3142771914 scopus 로고    scopus 로고
    • Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response
    • Saccani S, Marazzi I, Beg AA, Natoli G, (2004) Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. J Exp Med 200: 107-113.
    • (2004) J Exp Med , vol.200 , pp. 107-113
    • Saccani, S.1    Marazzi, I.2    Beg, A.A.3    Natoli, G.4
  • 29
    • 33745463549 scopus 로고    scopus 로고
    • The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells
    • Chae WJ, Henegariu O, Lee SK, Bothwell AL, (2006) The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells. Proc Natl Acad Sci U S A 103: 9631-9636.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9631-9636
    • Chae, W.J.1    Henegariu, O.2    Lee, S.K.3    Bothwell, A.L.4
  • 30
    • 34547821980 scopus 로고    scopus 로고
    • FOXP3 is a homooligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease
    • Li B, Samanta A, Song X, Iacono KT, Brennan P, et al. (2007) FOXP3 is a homooligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int Immunol 19: 825-835.
    • (2007) Int Immunol , vol.19 , pp. 825-835
    • Li, B.1    Samanta, A.2    Song, X.3    Iacono, K.T.4    Brennan, P.5
  • 31
    • 34447568209 scopus 로고    scopus 로고
    • Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT
    • Hu H, Djuretic I, Sundrud MS, Rao A, (2007) Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT. Trends Immunol 28: 329-332.
    • (2007) Trends Immunol , vol.28 , pp. 329-332
    • Hu, H.1    Djuretic, I.2    Sundrud, M.S.3    Rao, A.4
  • 32
    • 0025138985 scopus 로고
    • Delineation of an enhancerlike positive regulatory element in the interleukin-2 receptor alpha-chain gene
    • Lin BB, Cross SL, Halden NF, Roman DG, Toledano MB, et al. (1990) Delineation of an enhancerlike positive regulatory element in the interleukin-2 receptor alpha-chain gene. Mol Cell Biol 10: 850-853.
    • (1990) Mol Cell Biol , vol.10 , pp. 850-853
    • Lin, B.B.1    Cross, S.L.2    Halden, N.F.3    Roman, D.G.4    Toledano, M.B.5
  • 33
    • 0030851835 scopus 로고    scopus 로고
    • Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation
    • Kahn-Perles B, Lipcey C, Lecine P, Olive D, Imbert J, (1997) Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation. J Biol Chem 272: 21774-21783.
    • (1997) J Biol Chem , vol.272 , pp. 21774-21783
    • Kahn-Perles, B.1    Lipcey, C.2    Lecine, P.3    Olive, D.4    Imbert, J.5
  • 35
    • 34447542374 scopus 로고    scopus 로고
    • FoxP3 enhances HIV-1 gene expression by modulating NFkappaB occupancy at the long terminal repeat in human T cells
    • Holmes D, Knudsen G, Mackey-Cushman S, Su L, (2007) FoxP3 enhances HIV-1 gene expression by modulating NFkappaB occupancy at the long terminal repeat in human T cells. J Biol Chem 282: 15973-15980.
    • (2007) J Biol Chem , vol.282 , pp. 15973-15980
    • Holmes, D.1    Knudsen, G.2    Mackey-Cushman, S.3    Su, L.4
  • 36
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • Zhong H, May MJ, Jimi E, Ghosh S, (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9: 625-636.
    • (2002) Mol Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 37
    • 66149122282 scopus 로고    scopus 로고
    • Two modes of transcriptional activation at native promoters by NF-kappaB p65
    • van Essen D, Engist B, Natoli G, Saccani S, (2009) Two modes of transcriptional activation at native promoters by NF-kappaB p65. PLoS Biol 7: e73.
    • (2009) PLoS Biol , vol.7
    • van Essen, D.1    Engist, B.2    Natoli, G.3    Saccani, S.4
  • 38
    • 33847242598 scopus 로고    scopus 로고
    • Foxp3 occupancy and regulation of key target genes during T-cell stimulation
    • Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, et al. (2007) Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 445: 931-935.
    • (2007) Nature , vol.445 , pp. 931-935
    • Marson, A.1    Kretschmer, K.2    Frampton, G.M.3    Jacobsen, E.S.4    Polansky, J.K.5
  • 39
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng Y, Rudensky AY, (2007) Foxp3 in control of the regulatory T cell lineage. Nat Immunol 8: 457-462.
    • (2007) Nat Immunol , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 40
    • 77955486658 scopus 로고    scopus 로고
    • Genome-wide identification of human FOXP3 target genes in natural regulatory T cells
    • Sadlon TJ, Wilkinson BG, Pederson S, Brown CY, Bresatz S, et al. (2010) Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. J Immunol 185: 1071-1081.
    • (2010) J Immunol , vol.185 , pp. 1071-1081
    • Sadlon, T.J.1    Wilkinson, B.G.2    Pederson, S.3    Brown, C.Y.4    Bresatz, S.5


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