-
1
-
-
0348048874
-
Diabetic retinopathy
-
Frank RN. Diabetic retinopathy. N Engl J Med 2004;350:48-58
-
(2004)
N Engl J Med
, vol.350
, pp. 48-58
-
-
Frank, R.N.1
-
3
-
-
0031006861
-
Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy
-
Miller JW, Adamis AP, Aiello LP. Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy. Diabetes Metab Rev 1997;13:37-50
-
(1997)
Diabetes Metab Rev
, vol.13
, pp. 37-50
-
-
Miller, J.W.1
Adamis, A.P.2
Aiello, L.P.3
-
4
-
-
0842313052
-
Connective tissue growth factor is up-regulated in the diabetic retina: Amelioration by angiotensin-converting enzyme inhibition
-
Tikellis C, Cooper ME, Twigg SM, Burns WC, Tolcos M. Connective tissue growth factor is up-regulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition. Endocrinology 2004;145:860-866
-
(2004)
Endocrinology
, vol.145
, pp. 860-866
-
-
Tikellis, C.1
Cooper, M.E.2
Twigg, S.M.3
Burns, W.C.4
Tolcos, M.5
-
5
-
-
7044228789
-
A Central role for inflammation in the pathogenesis of diabetic retinopathy
-
Joussen AM, Poulaki V, Le ML, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 2004;18:1450-1452
-
(2004)
FASEB J
, vol.18
, pp. 1450-1452
-
-
Joussen, A.M.1
Poulaki, V.2
Le, M.L.3
-
6
-
-
0037600389
-
Diabetic retinopathy. Pathophysiology and therapy of hypoxia-induced inflammation
-
[in German]
-
Joussen AM, Fauser S, Krohne TU, Lemmen KD, Lang GE, Kirchhof B. [Diabetic retinopathy. Pathophysiology and therapy of hypoxia-induced inflammation] [in German]. Ophthalmologe 2003;100:363-370
-
(2003)
Ophthalmologe
, vol.100
, pp. 363-370
-
-
Joussen, A.M.1
Fauser, S.2
Krohne, T.U.3
Lemmen, K.D.4
Lang, G.E.5
Kirchhof, B.6
-
7
-
-
34247394257
-
Oxidative stress and diabetic retinopathy
-
Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp Diabetes Res 2007;2007:43603
-
(2007)
Exp Diabetes Res
, vol.2007
, pp. 43603
-
-
Kowluru, R.A.1
Chan, P.S.2
-
8
-
-
54949157448
-
Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives
-
Madsen-Bouterse SA, Kowluru RA. Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives. Rev Endocr Metab Disord 2008;9:315-327
-
(2008)
Rev Endocr Metab Disord
, vol.9
, pp. 315-327
-
-
Madsen-Bouterse, S.A.1
Kowluru, R.A.2
-
9
-
-
73549107654
-
Activation of the wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models
-
Chen Y, Hu Y, Zhou T, et al. Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models. Am J Pathol 2009;175:2676-2685
-
(2009)
Am J Pathol
, vol.175
, pp. 2676-2685
-
-
Chen, Y.1
Hu, Y.2
Zhou, T.3
-
10
-
-
8444251784
-
The wnt signaling pathway in development and disease
-
Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004;20:781-810
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
11
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in wnt/beta-catenin signaling: Arrows point the way
-
He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004; 131:1663-1677
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
12
-
-
47049121052
-
Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the wnt co-receptor LRP6
-
MacDonald BT, Yokota C, Tamai K, Zeng X, He X. Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6. J Biol Chem 2008;283:16115-16123
-
(2008)
J Biol Chem
, vol.283
, pp. 16115-16123
-
-
MacDonald, B.T.1
Yokota, C.2
Tamai, K.3
Zeng, X.4
He, X.5
-
13
-
-
28644439005
-
A dual-kinase mechanism for wnt co-receptor phosphorylation and activation
-
Zeng X, Tamai K, Doble B, et al. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 2005;438:873-877
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
-
14
-
-
0038745735
-
Beta-catenin regulates vascular endothelial growth factor expression in colon cancer
-
Easwaran V, Lee SH, Inge L, et al. beta-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res 2003;63:3145-3153
-
(2003)
Cancer Res
, vol.63
, pp. 3145-3153
-
-
Easwaran, V.1
Lee, S.H.2
Inge, L.3
-
15
-
-
77954272869
-
Inhibition of connective tissue growth factor overexpression in diabetic retinopathy by SERPINA3K via blocking the WNT/beta-catenin pathway
-
Zhang B, Zhou KK, Ma JX. Inhibition of connective tissue growth factor overexpression in diabetic retinopathy by SERPINA3K via blocking the WNT/beta-catenin pathway. Diabetes 2010;59:1809-1816
-
(2010)
Diabetes
, vol.59
, pp. 1809-1816
-
-
Zhang, B.1
Zhou, K.K.2
Ma, J.X.3
-
16
-
-
38949194936
-
Initiation of wnt signaling: Control of wnt coreceptor lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
Zeng X, Huang H, Tamai K, et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 2008;135:367-375
-
(2008)
Development
, vol.135
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
-
17
-
-
77957348383
-
The pathogenic role of the canonical wnt pathway in age-related macular degeneration
-
Zhou T, Hu Y, Chen Y, et al. The pathogenic role of the canonical Wnt pathway in age-related macular degeneration. Invest Ophthalmol Vis Sci 2010;51:4371-4379
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 4371-4379
-
-
Zhou, T.1
Hu, Y.2
Chen, Y.3
-
18
-
-
77951050199
-
Blocking the wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family
-
Zhang B, Abreu JG, Zhou K, et al. Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family. Proc Natl Acad Sci USA 2010;107:6900-6905
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6900-6905
-
-
Zhang, B.1
Abreu, J.G.2
Zhou, K.3
-
19
-
-
79960341497
-
Identification of a novel inhibitor of the canonical wnt pathway
-
Park K, Lee K, Zhang B, et al. Identification of a novel inhibitor of the canonical Wnt pathway. Mol Cell Biol 2011;31:3038-3051
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3038-3051
-
-
Park, K.1
Lee, K.2
Zhang, B.3
-
20
-
-
0036228537
-
Difference in ischemic regulation of vascular endothelial growth factor and pigment epithelium - Derived factor in brown norway and sprague dawley rats contributing to different susceptibilities to retinal neovascularization
-
Gao G, Li Y, Fant J, Crosson CE, Becerra SP, Ma JX. Difference in ischemic regulation of vascular endothelial growth factor and pigment epithelium - derived factor in brown norway and sprague dawley rats contributing to different susceptibilities to retinal neovascularization. Diabetes 2002;51: 1218-1225
-
(2002)
Diabetes
, vol.51
, pp. 1218-1225
-
-
Gao, G.1
Li, Y.2
Fant, J.3
Crosson, C.E.4
Becerra, S.P.5
Ma, J.X.6
-
21
-
-
0035096388
-
Sensitive blood-retinal barrier breakdown quantitation using evans blue
-
Xu Q, Qaum T, Adamis AP. Sensitive blood-retinal barrier breakdown quantitation using Evans blue. Invest Ophthalmol Vis Sci 2001;42:789-794
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 789-794
-
-
Xu, Q.1
Qaum, T.2
Adamis, A.P.3
-
22
-
-
0035882030
-
Regulation of vascular endothelial growth factor by the wnt and K-ras pathways in colonic neoplasia
-
Zhang X, Gaspard JP, Chung DC. Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. Cancer Res 2001;61:6050-6054
-
(2001)
Cancer Res
, vol.61
, pp. 6050-6054
-
-
Zhang, X.1
Gaspard, J.P.2
Chung, D.C.3
-
23
-
-
78951469821
-
The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy
-
Zhou T, Zhou KK, Lee K, et al. The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy. Diabetologia 2011;54:459-468
-
(2011)
Diabetologia
, vol.54
, pp. 459-468
-
-
Zhou, T.1
Zhou, K.K.2
Lee, K.3
-
24
-
-
80054027552
-
Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier
-
Paes KT, Wang E, Henze K, et al. Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Invest Ophthalmol Vis Sci 2011;52:6452-6461
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 6452-6461
-
-
Paes, K.T.1
Wang, E.2
Henze, K.3
-
25
-
-
12144289950
-
Vascular development in the retina and inner ear: Control by norrin and frizzled-4, a high-affinity ligand-receptor pair
-
Xu Q, Wang Y, Dabdoub A, et al. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 2004;116:883-895
-
(2004)
Cell
, vol.116
, pp. 883-895
-
-
Xu, Q.1
Wang, Y.2
Dabdoub, A.3
-
26
-
-
34547797469
-
Vascular injury during elevated glucose can be mitigated by erythropoietin and wnt signaling
-
Chong ZZ, Shang YC, Maiese K. Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling. Curr Neurovasc Res 2007;4:194-204
-
(2007)
Curr Neurovasc Res
, vol.4
, pp. 194-204
-
-
Chong, Z.Z.1
Shang, Y.C.2
Maiese, K.3
-
27
-
-
0035954281
-
Head inducer dickkopf-1 is a ligand for wnt coreceptor LRP6
-
Semënov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 2001;11:951-961
-
(2001)
Curr Biol
, vol.11
, pp. 951-961
-
-
Semënov, M.V.1
Tamai, K.2
Brott, B.K.3
Kühl, M.4
Sokol, S.5
He, X.6
-
28
-
-
47549113841
-
IGFBP-4 is an inhibitor of canonical wnt signalling required for cardiogenesis
-
Zhu W, Shiojima I, Ito Y, et al. IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. Nature 2008;454:345-349
-
(2008)
Nature
, vol.454
, pp. 345-349
-
-
Zhu, W.1
Shiojima, I.2
Ito, Y.3
-
29
-
-
0033289483
-
Regulators of vascular permeability: Potential sites for intervention in the treatment of macular edema
-
Gillies MC. Regulators of vascular permeability: potential sites for intervention in the treatment of macular edema. Doc Ophthalmol 1999;97: 251-260
-
(1999)
Doc Ophthalmol
, vol.97
, pp. 251-260
-
-
Gillies, M.C.1
-
30
-
-
23144443684
-
Old and new drug targets in diabetic retinopathy: From biochemical changes to inflammation and neurodegeneration
-
Leal EC, Santiago AR, Ambrósio AF. Old and new drug targets in diabetic retinopathy: from biochemical changes to inflammation and neurodegeneration. Curr Drug Targets CNS Neurol Disord 2005;4:421-434
-
(2005)
Curr Drug Targets CNS Neurol Disord
, vol.4
, pp. 421-434
-
-
Leal, E.C.1
Santiago, A.R.2
Ambrósio, A.F.3
-
31
-
-
70349816653
-
Eyeing up new wnt pathway players
-
Clevers H. Eyeing up new Wnt pathway players. Cell 2009;139:227-229
-
(2009)
Cell
, vol.139
, pp. 227-229
-
-
Clevers, H.1
-
32
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical wnt signaling pathway
-
Mao J, Wang J, Liu B, et al. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 2001;7:801-809
-
(2001)
Mol Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
-
33
-
-
77958599987
-
Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies
-
Gong Y, Bourhis E, Chiu C, et al. Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. PLoS ONE 2010;5:e12682
-
(2010)
PLoS ONE
, vol.5
-
-
Gong, Y.1
Bourhis, E.2
Chiu, C.3
-
34
-
-
79955663810
-
Anti-VEGF compounds in the treatment of neovascular age related macular degeneration
-
Campa C, Harding SP. Anti-VEGF compounds in the treatment of neovascular age related macular degeneration. Curr Drug Targets 2011;12:173-181
-
(2011)
Curr Drug Targets
, vol.12
, pp. 173-181
-
-
Campa, C.1
Harding, S.P.2
-
35
-
-
77949436790
-
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema
-
Parravano M, Menchini F, Virgili G. Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema. Cochrane Database Syst Rev 2009 (4):CD007419
-
(2009)
Cochrane Database Syst Rev
, Issue.4
-
-
Parravano, M.1
Menchini, F.2
Virgili, G.3
-
36
-
-
33744728068
-
Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization
-
Jo N, Mailhos C, Ju M, et al. Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization. Am J Pathol 2006; 168:2036-2053
-
(2006)
Am J Pathol
, vol.168
, pp. 2036-2053
-
-
Jo, N.1
Mailhos, C.2
Ju, M.3
-
38
-
-
33744472747
-
Wnt/frizzled signaling in the vasculature: New angiogenic factors in sight
-
Masckauchán TN, Kitajewski J. Wnt/Frizzled signaling in the vasculature: new angiogenic factors in sight. Physiology (Bethesda) 2006;21: 181-188
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 181-188
-
-
Masckauchán, T.N.1
Kitajewski, J.2
|