Regulators of vascular permeability: Potential sites for intervention in the treatment of macular edema

Documenta Ophthalmologica

Volumn 97, Issue 3-4, 1999, Pages 251-260

  Gillies, Mark C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Blood retinal barrier; Drug therapy; Endothelium; Permeability; Protein kinase C; Tyrosine phosphorylation; Vascular

Indexed keywords

CALCIUM; CYCLIC AMP; CYTOKINE; FORMOTEROL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; TYROSINE;

BLOOD RETINA BARRIER; CLINICAL TRIAL; CONFERENCE PAPER; HUMAN; PERMEABILITY; PROTEIN PHOSPHORYLATION; RETINA MACULA EDEMA; VASCULAR ENDOTHELIUM; ANIMAL; CAPILLARY PERMEABILITY; DRUG EFFECT; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RETINA MACULA CYSTOID EDEMA; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD-RETINAL BARRIER; CAPILLARY PERMEABILITY; ENDOTHELIUM, VASCULAR; HUMANS; MACULAR EDEMA, CYSTOID; PHOSPHORYLATION; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0033289483     PISSN: 00124486     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1002196930726     Document Type: Article

References (3)

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2. Aiello LP, Bursell SE, Clermont A, Duh E, Ishii H, Takagi C, Mori F, Ciulla TA, Ways K, Jirousek M, Smith LE, King GL. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes 1997; 46: 1473-80 .
3. Greenwood J. Astrocyes, cerebral endothelium, and cell culture. The pursuit of an in vitro blood-brain barrier. Ann NY Acad Sci 1991; 633: 426-1.