Treatment with pharmacological PPARα agonists stimulates the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 1, 2013, Pages 2105-2117

  Ringseis, Robert ^a   Keller, Janine ^a   Lukas, Isabel ^a   Spielmann, Julia ^b   Most, Erika ^a   Couturier, Aline ^a   König, Bettina ^b   Hirche, Frank ^b   Stangl, Gabriele I ^b   Wen, Gaiping ^a   Eder, Klaus ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Atrogin 1; MuRF1; Muscle atrophy; Peroxisome proliferator activated receptor ; Ubiquitin proteasome system

Indexed keywords

3 METHYLHISTIDINE; ATROGIN 1; CLOFIBRATE; MESSENGER RNA; MUSCLE PROTEIN; MUSCLE RING FINGER 1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PIRINIXIC ACID; PROTEASOME; PROTEIN AKT1; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME REGULATION; EXTENSOR DIGITORUM LONGUS MUSCLE; FOOD INTAKE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOME SIZE; HUMAN; HUMAN CELL; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; QUADRICEPS FEMORIS MUSCLE; RAT; RECEPTOR UPREGULATION; REPORTER GENE; SIGNAL TRANSDUCTION; UBIQUITIN PROTEASOME PATHWAY; UBIQUITINATION; WILD TYPE;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CLOFIBRATE; HUMANS; HYPERLIPIDEMIAS; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PPAR ALPHA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PYRIMIDINES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; UBIQUITIN; UBIQUITINATION; UP-REGULATION;

MUS; RATTUS; RODENTIA;

EID: 84867896488     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.09.024     Document Type: Article

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