Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 2, 2012, Pages 272-280

  Beck Broichsitter, Moritz ^a,b   Kleimann, Pia ^a   Schmehl, Thomas ^a   Betz, Thomas ^b   Bakowsky, Udo ^b   Kissel, Thomas ^b   Seeger, Werner ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Aerosol; Biodegradable nanoparticles; Freeze drying; Lyoprotectants; Pulmonary drug delivery; Vibrating mesh nebulizer

Indexed keywords

LYOPROTECTANT; NANOPARTICLE; POLYGLACTIN; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FREEZE THAWING; HUMAN; MESH SLING; NEBULIZATION; NEBULIZER; PHYSICAL CHEMISTRY; PREDICTION; REHYDRATION; SURFACE TENSION; TEMPERATURE DEPENDENCE; ULTRASOUND; VISCOSITY;

AEROSOLS; AIR; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FREEZE DRYING; LACTIC ACID; NANOPARTICLES; NEBULIZERS AND VAPORIZERS; POLYGLYCOLIC ACID; SOLUTIONS; SURFACE TENSION; TEMPERATURE; ULTRASONICS; VIBRATION; VISCOSITY;

EID: 84867890649     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.07.004     Document Type: Article

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