The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: Increased role of L-type Ca2+ channels

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 11, 2012, Pages 1141-1148

  Balkanci, Zeynep Dicle ^a   Pehlivanoǧlu, Bilge ^a   Bayrak, Sibel ^a   Karabulut, Ismail ^a   Karaismailoǧlu, Serkan ^a   Erdem, Ayśen ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Detrusor smooth muscle; High fat diet; L type Ca +2 channel; Muscarinic receptors; Nifedipine; Rho kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; CALCIUM CHANNEL L TYPE; CARBACHOL; CHOLESTEROL; METHOCTRAMINE; NIFEDIPINE; POTASSIUM; POTASSIUM CHLORIDE; RHO KINASE;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; ATTENUATION; BLADDER FUNCTION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DETRUSOR MUSCLE; DETRUSOR SMOOTH MUSCLE; DRUG EFFICACY; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; INCUBATION TIME; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTION; TREATMENT DURATION;

AMIDES; ANIMALS; CALCIUM CHANNELS, L-TYPE; CARBACHOL; CHOLINERGIC AGONISTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERCHOLESTEROLEMIA; MALE; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NIFEDIPINE; POTASSIUM CHLORIDE; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; URINARY BLADDER;

EID: 84867866616     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0784-5     Document Type: Article

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