Docosahexanoic acid improves chemotherapy efficacy by inducing CD95 translocation to lipid rafts in ER2 breast cancer cells

Lipids

Volumn 47, Issue 11, 2012, Pages 1019-1030

  Ewaschuk, Julia B ^a   Newell, Marnie ^a   Field, Catherine J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Apoptosis; Breast cancer; CD95; Cell death; Chemotherapy; FADD; N 3 Polyunsaturated fatty acids

Indexed keywords

DOCOSAHEXAENOIC ACID; DOXORUBICIN; ESTROGEN RECEPTOR; FAS ANTIGEN; ICOSAPENTAENOIC ACID; TRASTUZUMAB;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL GROWTH; CELL METABOLISM; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; ESTROGEN RECEPTOR NEGATIVE BREAST CANCER; LIPID RAFT; MONOTHERAPY; PROTEIN LOCALIZATION;

ANTIGENS, CD95; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CELL PROLIFERATION; CELL SURVIVAL; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; EICOSAPENTAENOIC ACID; FEMALE; HUMANS; MCF-7 CELLS; MEMBRANE MICRODOMAINS; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84867863127     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-012-3717-7     Document Type: Article

References (49)

1. Bougnoux P, Maillard V, Chajes V (2005) Omega-6/omega-3 polyunsaturated fatty acids ratio and breast cancer. World Rev Nutr Diet 94:158-165
2. Karmali RA, Marsh J, Fuchs C (1984) Effect of omega-3 fatty acids on growth of a rat mammary tumor. J Natl Cancer Inst 73:457-461
3. Rose DP, Connolly JM (1999) Omega-3 fatty acids as cancer chemopreventive agents. Pharmacol Ther 83:217-244
4. Schley PD, Jijon HB, Robinson LE, Field CJ (2005) Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells. Breast Cancer Res Treat 92:187-195
5. Schley PD, Brindley DN, Field CJ (2007) (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells. J Nutr 137:548-553
6. Bernard-Gallon DJ, Vissac-Sabatier C, Antoine-Vincent D, Rio PG, Maurizis J-C, Fustier P, Bignon Y-J (2002) Differential effects of n-3 and n-6 polyunsaturated fatty acids on BRCA1 and BRCA2 gene expression in breast cell lines. Br J Nutr 87:281-289
7. Baumgartner M, Sturlan S, Roth E, Wessner B, Bachleitner-Hofmann T (2004) Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells. Int J Cancer 112:707-712
8. Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, Lupu R (2004) Overexpression and hyperactivityofbreast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. Int J Oncol 24:1369-1383
9. Biondo PD, Brindley DN, Sawyer MB, Field CJ (2008) The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapy. J Nutr Biochem 19:787-796
10. Grammatikos SI, Subbaiah PV, Victor TA, Miller WM (1994) n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. Br J Cancer 70:219-227
11. Chajes V, Sattler W, Stranzl A, Kostner GM (1995) Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. Breast Cancer Res Treat 34:199-212
12. Begin ME, Ells G, Horrobin DF (1988) Polyunsaturated fatty acid-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation. J Natl Cancer Inst 80:188-194
13. Yamamoto D, Kiyozuka Y, Adachi Y, Takada H, Hioki K, Tsubura A (1999) Synergistic action of apoptosis induced by eicosapentaenoic acid and TNP-470 on human breast cancer cells. Breast Cancer Res Treat 55:149-160
14. Tsujita-Kyutoku M, Yuri T, Danbara N, Senzaki H, Kiyozuka Y, Uehara N, Takada H, Hada T, Miyazawa T, Ogawa Y, Tsubura A (2004) Conjugated docosahexaenoic acid suppresses KPL-1 human breast cancer cell growth in vitro and in vivo: potential mechanisms of action. Breast Cancer Res 6:R291-R299
15. Simons K, Toomre D (2000) Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1:31-39
16. Shaw AS (2006) Lipid rafts: now you see them, now you don't. Nat Immunol 7:1139-1142
17. Foster LJ, De Hoog CL, Mann M (2003) Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors. Proc Natl Acad Sci USA 100:5813-5818
18. Brown DA, London E (1998) Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 14:111-136
19. Hatala MA, Rayburn J, Rose DP (1994) Comparison of linoleic acid and eicosapentaenoic acid incorporation into human breast cancer cells. Lipids 29:831-837
20. Rose DP, Connolly JM, Rayburn J, Coleman M (1995) Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cell in nude mice. J Natl Cancer Inst 87:587-592
21. Robinson LE, Clandinin MT, Field CJ (2002) The role of dietary long-chain n-3 fatty acids in anti-cancer immune defense and R3230AC mammary tumor growth in rats: influence of diet fat composition. Breast Cancer Res Treat 73:145-160
22. Rockett BD, Franklin A, Harris M, Teague H, Rockett A, Shaikh SR (2011) Membrane raft organization is more sensitive to disruption by (n-3) PUFA than nonraft organization in EL4 and B cells. J Nutr 141:1041-1048
23. Bougnoux P, Germain E, Chajes V, Hubert B, Lhuillery C, Le FO, Body G, Calais G (1999) Cytotoxic drugs efficacy correlates with adipose tissue docosahexaenoic acid level in locally advanced breast carcinoma. Br J Cancer 79:1765-1769
24. Bougnoux P, Hajjaji N, Ferrasson MN, Giraudeau B, Couet C, Le FO (2009) Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial. Br J Cancer 101:1978-1985
25. Siddiqui RA, Harvey KA, Xu Z, Bammerlin EM, Walker C, Altenburg JD (2011) Docosahexaenoic acid: a natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects. BioFactors 37:399-412
26. Barnhart BC, Alappat EC, Peter ME (2003) The CD95 type I/type II model. Semin Immunol 15:185-193
27. Fulda S, Strauss G, Meyer E, Debatin KM (2000) Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells. Blood 95:301-308
28. Bollinger CR, Teichgraber V, Gulbins E (2005) Ceramide-enri-ched membrane domains. Biochim Biophys Acta 1746:284-294
29. Kim HS, Lee YS, Kim DK (2009) Doxorubicin exerts cytotoxic effects through cell cycle arrest and Fas-mediated cell death. Pharmacology 84:300-309
30. Blanckaert V, Ulmann L, Mimouni V, Antol J, Brancquart L, Chenais B (2010) Docosahexaenoic acid intake decreases proliferation, increases apoptosis and decreases the invasive potential of the human breast carcinoma cell line MDA-MB-231. Int J Oncol 36:737-742
31. Patterson RE, Flatt SW, Newman VA, Natarajan L, Rock CL, Thomson CA, Caan BJ, Parker BA, Pierce JP (2011) Marine fatty acid intake is associated with breast cancer prognosis. J Nutr 141:201-206
32. Kang KS, Wang P, Yamabe N, Fukui M, Jay T, Zhu BT (2010) Docosahexaenoic acid induces apoptosis in MCF-7 cells in vitro and in vivo via reactive oxygen species formation and caspase 8 activation. PLoS One 5:e10296
33. Shaikh IA, Brown I, Schofield AC, Wahle KW, Heys SD (2008) Docosahexaenoic acid enhances the efficacy of docetaxel in prostate cancer cells by modulation of apoptosis: the role of genes associated with the NF-kappaB pathway. Prostate 68:1635-1646
34. Sawyer M, Field CJ (2010) Possible mechanisms for omega-3 (n-3) the anti-tumour action. In: Carviello G, Serini S (eds) Diet and Cancer. Springer, New York
35. Wendel M, Heller AR (2009) Anticancer actions of omega-3 fatty acids - current state and future perspectives. Anticancer Agents Med Chem 9:457-470
36. Rickert RC, Jellusova J, Miletic AV (2011) Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease. Immunol Rev 244:115-133
37. Grassme H, Jekle A, Riehle A, Schwarz H, Berger J, Sandhoff K, Kolesnick R, Gulbins E (2001) CD95 signaling via ceramide-rich membrane rafts. J Biol Chem 276:20589-20596
38. Blank N, Schiller M, Krienke S, Wabnitz G, Ho AD, Lorenz HM (2007) Cholera toxin binds to lipid rafts but has a limited specificity for ganglioside GM1. Immunol Cell Biol 85:378-382
39. Kenworthy AK, Petranova N, Edidin M (2000) High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. Mol Biol Cell 11:1645-1655
40. Shaikh SR, Rockett BD, Salameh M, Carraway K (2009) Doco-sahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells. J Nutr 139:1632-1639
41. Alquobaili F, Miller SA, Muhie S, Day A, Jett M, Hammamieh R (2010) Estrogen receptor-dependent genomic expression profiles in breast cancer cells in response to fatty acids. J Carcinog 8:17
42. Fan YY, Ly LH, Barhoumi R, McMurray DN, Chapkin RS (2004) Dietary docosahexaenoic acid suppressesTcell protein kinaseCtheta lipid raft recruitment and IL-2 production. J Immunol 173:6151-6160
43. Altenburg JD, Siddiqui RA (2009) Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells. Mol Cancer Res 7:1013-1020
44. Vibet S, Goupille C, Bougnoux P, Steghens JP, Gore J, Maheo K (2008) Sensitization by docosahexaenoic acid (DHA) of breast cancer cells to anthracyclines through loss of glutathione peroxidase (GPx1) response. Free Radic Biol Med 44:1483-1491
45. Ruth MR, Proctor SD, Field CJ (2009) Feeding long-chain n-3 polyunsaturated fatty acids to obese leptin receptor-deficient JCR: lA-cp rats modifies immune function and lipid-raft fatty acid composition. Br J Nutr 101:1341-1350
46. Carpinteiro A, Dumitru C, Schenck M, Gulbins E (2008) Ceramide-induced cell death in malignant cells. Cancer Lett 264:1-10
47. Ogretmen B, Hannun YA (2004) Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer 4:604-616
48. Kawase M, Watanabe M, Kondo T, Yabu T, Taguchi Y, Umehara H, Uchiyama T, Mizuno K, Okazaki T (2002) Increase of ceramide in adriamycin-induced HL-60 cell apoptosis: detection by a novel anti-ceramide antibody. Biochim Biophys Acta 1584:104-114
49. Dawood S, Ueno NT, Valero V, Woodward WA, Buchholz TA, Hortobagyi GN, Gonzalez-Angulo AM, Cristofanilli M (2011) Identifying factors that impact survival among women with inflammatory breast cancer. Ann Oncol 23(4):870-875