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Volumn 7, Issue 7, 2009, Pages 1013-1020

Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; CHEMOKINE RECEPTOR CXCR4; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; METHYL BETA CYCLODEXTRIN; OMEGA 3 FATTY ACID; STEARIC ACID;

EID: 67651160516     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0385     Document Type: Article
Times cited : (61)

References (47)
  • 1
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-6.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 2
    • 0033051750 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Biology and clinical relevance in inflammation and AIDS
    • Locati M, Murphy PM. Chemokines and chemokine receptors: biology and clinical relevance in inflammation and AIDS. Annu Rev Med 1999;50: 425-40.
    • (1999) Annu Rev Med , vol.50 , pp. 425-440
    • Locati, M.1    Murphy, P.M.2
  • 3
    • 0032509889 scopus 로고    scopus 로고
    • Chemokines - chemotactic cytokines that mediate inflammation
    • Luster AD. Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med 1998;338:436-45.
    • (1998) N Engl J Med , vol.338 , pp. 436-445
    • Luster, A.D.1
  • 4
    • 27144457455 scopus 로고    scopus 로고
    • The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer
    • Kang H, Watkins G, Douglas-Jones A, Mansel RE, Jiang WG. The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer. Breast 2005;14:360-7.
    • (2005) Breast , vol.14 , pp. 360-367
    • Kang, H.1    Watkins, G.2    Douglas-Jones, A.3    Mansel, R.E.4    Jiang, W.G.5
  • 5
    • 33748873913 scopus 로고    scopus 로고
    • Chemokines and cancer
    • Zlotnik A. Chemokines and cancer. Int J Cancer 2006;119:2026-9.
    • (2006) Int J Cancer , vol.119 , pp. 2026-2029
    • Zlotnik, A.1
  • 6
    • 34247468926 scopus 로고    scopus 로고
    • Chemokine networks and breast cancer metastasis
    • Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Dis 2006;26:75-85.
    • (2006) Breast Dis , vol.26 , pp. 75-85
    • Karnoub, A.E.1    Weinberg, R.A.2
  • 7
    • 33947410027 scopus 로고    scopus 로고
    • Inhibition of CXCR4-mediated breast cancer metastasis: A potential role for heparinoids?
    • Harvey JR, Mellor P, Eldaly H, Lennard TW, Kirby JA, Ali S. Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids? Clin Cancer Res 2007;13:1562-70.
    • (2007) Clin Cancer Res , vol.13 , pp. 1562-1570
    • Harvey, J.R.1    Mellor, P.2    Eldaly, H.3    Lennard, T.W.4    Kirby, J.A.5    Ali, S.6
  • 8
    • 0142102523 scopus 로고    scopus 로고
    • T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer
    • Tamamura H, Hori A, Kanzak N, et al. T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer. FEBS Lett 2003;550:79-83.
    • (2003) FEBS Lett , vol.550 , pp. 79-83
    • Tamamura, H.1    Hori, A.2    Kanzak, N.3
  • 9
    • 33644789290 scopus 로고    scopus 로고
    • Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
    • Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel R, Jiang W. Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 2005;7:R402-10.
    • (2005) Breast Cancer Res , vol.7
    • Kang, H.1    Watkins, G.2    Parr, C.3    Douglas-Jones, A.4    Mansel, R.5    Jiang, W.6
  • 10
    • 0042941765 scopus 로고    scopus 로고
    • Down-regulation of CXCR4 byinducible small interfering RNA inhibits breast cancer cell invasion in vitro
    • Chen Y, Stamatoyannopoulos G, Song CZ. Down-regulation of CXCR4 byinducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res 2003;63:4801-4.
    • (2003) Cancer Res , vol.63 , pp. 4801-4804
    • Chen, Y.1    Stamatoyannopoulos, G.2    Song, C.Z.3
  • 11
    • 9444239192 scopus 로고    scopus 로고
    • Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
    • Darash-Yahana M, Pikarsky E, Abramovitch R, et al. Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J 2004;18:1240-2.
    • (2004) FASEB J , vol.18 , pp. 1240-1242
    • Darash-Yahana, M.1    Pikarsky, E.2    Abramovitch, R.3
  • 12
    • 33747109086 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer
    • Dewan MZ, Ahmed S, Iwasaki Y, Ohba K, Toi M, Yamamoto N. Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer. Biomed Pharmacother 2006;60:273-6.
    • (2006) Biomed Pharmacother , vol.60 , pp. 273-276
    • Dewan, M.Z.1    Ahmed, S.2    Iwasaki, Y.3    Ohba, K.4    Toi, M.5    Yamamoto, N.6
  • 13
    • 0942301172 scopus 로고    scopus 로고
    • Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
    • Fernandis AZ, Prasad A, Band H, Klosel R, Ganju RK. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 2004;23:157-67.
    • (2004) Oncogene , vol.23 , pp. 157-167
    • Fernandis, A.Z.1    Prasad, A.2    Band, H.3    Klosel, R.4    Ganju, R.K.5
  • 14
    • 0038498102 scopus 로고    scopus 로고
    • NF-κB promotes breast cancer cell migration and metastasis byin ducing the expression of the chemokine receptor CXCR4
    • Helbig G, Christopherson KW 2nd, Bhat-Nakshatri P, et al. NF-κB promotes breast cancer cell migration and metastasis byin ducing the expression of the chemokine receptor CXCR4. J Biol Chem 2003;278:21631-8.
    • (2003) J Biol Chem , vol.278 , pp. 21631-21638
    • Helbig, G.1    Christopherson 2nd, K.W.2    Bhat-Nakshatri, P.3
  • 15
    • 33750447940 scopus 로고    scopus 로고
    • Dimerization of CXCR4 in living malignant cells: Control of cell migration bya synthetic peptide that reduces homologous CXCR4 interactions
    • Wang J, He L, Combs CA, Roderiquez G, Norcross MA. Dimerization of CXCR4 in living malignant cells: control of cell migration bya synthetic peptide that reduces homologous CXCR4 interactions. Mol Cancer Ther 2006;5: 2474-83.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2474-2483
    • Wang, J.1    He, L.2    Combs, C.A.3    Roderiquez, G.4    Norcross, M.A.5
  • 17
    • 0015369932 scopus 로고
    • Plasma lipids and lipoproteins in Greenlandic west coast Eskimos
    • Bang HO, Dyerberg J. Plasma lipids and lipoproteins in Greenlandic west coast Eskimos. Acta Med Scand 1972;192:85-94.
    • (1972) Acta Med Scand , vol.192 , pp. 85-94
    • Bang, H.O.1    Dyerberg, J.2
  • 18
    • 0027964534 scopus 로고
    • Longchain serum fattyacids and risk of thyroid cancer: A population-based case-control study in Norway
    • Berg JP, Glattre E, Haldorsen T, et al. Longchain serum fattyacids and risk of thyroid cancer: a population-based case-control study in Norway. Cancer Cause Control 1994;5:433-9.
    • (1994) Cancer Cause Control , vol.5 , pp. 433-439
    • Berg, J.P.1    Glattre, E.2    Haldorsen, T.3
  • 19
    • 0032786257 scopus 로고    scopus 로고
    • Effects of reduced dietarylinoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice
    • Connolly JM, Gilhooly EM, Rose DP. Effects of reduced dietarylinoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice. Nutr Cancer 1999;35:44-9.
    • (1999) Nutr Cancer , vol.35 , pp. 44-49
    • Connolly, J.M.1    Gilhooly, E.M.2    Rose, D.P.3
  • 20
    • 0031036793 scopus 로고    scopus 로고
    • Chemoprevention of DMBA-induced mammaryca rcinogenesis in rats by low-dose EPA and DHA
    • Noguchi M, Minami M, Yagasaki R, et al. Chemoprevention of DMBA-induced mammaryca rcinogenesis in rats by low-dose EPA and DHA. Br J Cancer 1997;75:348-53.
    • (1997) Br J Cancer , vol.75 , pp. 348-353
    • Noguchi, M.1    Minami, M.2    Yagasaki, R.3
  • 21
    • 0033228435 scopus 로고    scopus 로고
    • Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice
    • Rose DP, Connolly JM. Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. Int J Oncol 1999;15:1011-5.
    • (1999) Int J Oncol , vol.15 , pp. 1011-1015
    • Rose, D.P.1    Connolly, J.M.2
  • 22
    • 26444585580 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids attenuate breast cancer growth through activation of a neutral sphingomyelinase-mediated pathway
    • Wu M, Harvey KA, Ruzmetov N, et al. Omega-3 polyunsaturated fatty acids attenuate breast cancer growth through activation of a neutral sphingomyelinase-mediated pathway. Int J Cancer 2005;117:340-8.
    • (2005) Int J Cancer , vol.117 , pp. 340-348
    • Wu, M.1    Harvey, K.A.2    Ruzmetov, N.3
  • 23
    • 4444221731 scopus 로고    scopus 로고
    • Oleic and docosahexaenoic acid differentiallypha se separate from lipid raft molecules: A comparative NMR, DSC, AFM, and detergent extraction study
    • Shaikh SR, Dumaual AC, Castillo A, et al. Oleic and docosahexaenoic acid differentiallypha se separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. Biophys J 2004;87:1752-66.
    • (2004) Biophys J , vol.87 , pp. 1752-1766
    • Shaikh, S.R.1    Dumaual, A.C.2    Castillo, A.3
  • 24
    • 34548791071 scopus 로고    scopus 로고
    • Docosahexaenoic acid affects endothelial nitric oxide synthase in caveolae
    • Li Q, Zhang Q, Wang M, et al. Docosahexaenoic acid affects endothelial nitric oxide synthase in caveolae. Arch Biochem Biophys 2007;466:250-9.
    • (2007) Arch Biochem Biophys , vol.466 , pp. 250-259
    • Li, Q.1    Zhang, Q.2    Wang, M.3
  • 25
    • 33845612240 scopus 로고    scopus 로고
    • Eicosapentaenoic acid modifies lipid composition in caveolae and induces translocation of endothelial nitric oxide synthase
    • Li Q, Zhang Q, Wang M, et al. Eicosapentaenoic acid modifies lipid composition in caveolae and induces translocation of endothelial nitric oxide synthase. Biochimie 2007;89:169-77.
    • (2007) Biochimie , vol.89 , pp. 169-177
    • Li, Q.1    Zhang, Q.2    Wang, M.3
  • 26
    • 33846630404 scopus 로고    scopus 로고
    • Modulation of lipid rafts by ω-3 fattyacids in inflammation and cancer: Implications for use of lipids during nutrition support
    • Siddiqui RA, Harvey KA, Zaloga GP, Stillwell W. Modulation of lipid rafts by ω-3 fattyacids in inflammation and cancer: implications for use of lipids during nutrition support. Nutr Clin Pract 2007;22:74-88.
    • (2007) Nutr Clin Pract , vol.22 , pp. 74-88
    • Siddiqui, R.A.1    Harvey, K.A.2    Zaloga, G.P.3    Stillwell, W.4
  • 27
    • 23844530896 scopus 로고    scopus 로고
    • CCR7 and CXCR4 as novel biomarkers predicting axillaryly mph node metastasis in T1 breast cancer
    • Cabioglu N, Yazici MS, Arun B, et al. CCR7 and CXCR4 as novel biomarkers predicting axillaryly mph node metastasis in T1 breast cancer. Clin Cancer Res 2005;11:5686-93.
    • (2005) Clin Cancer Res , vol.11 , pp. 5686-5693
    • Cabioglu, N.1    Yazici, M.S.2    Arun, B.3
  • 28
    • 33746051169 scopus 로고    scopus 로고
    • Chemokines, chemokine receptors, and cancer metastasis
    • Kakinuma T, Hwang ST. Chemokines, chemokine receptors, and cancer metastasis. J Leukoc Biol 2006;79:639-51.
    • (2006) J Leukoc Biol , vol.79 , pp. 639-651
    • Kakinuma, T.1    Hwang, S.T.2
  • 29
    • 33947169954 scopus 로고    scopus 로고
    • (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells
    • Schley PD, Brindley DN, Field CJ. (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells. J Nutr 2007;137:548-53.
    • (2007) J Nutr , vol.137 , pp. 548-553
    • Schley, P.D.1    Brindley, D.N.2    Field, C.J.3
  • 30
    • 24344438206 scopus 로고    scopus 로고
    • Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts
    • Li Q, Wang M, Tan L, et al. Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts. J Lipid Res 2005;46: 1904-13.
    • (2005) J Lipid Res , vol.46 , pp. 1904-1913
    • Li, Q.1    Wang, M.2    Tan, L.3
  • 31
    • 0029120852 scopus 로고
    • Cellular cholesterol efflux mediated bycy clodextrins
    • Kilsdonk EPC, Yancey PG, Stoudt GW, et al. Cellular cholesterol efflux mediated bycy clodextrins. J Biol Chem 1995;270:17250-6.
    • (1995) J Biol Chem , vol.270 , pp. 17250-17256
    • Kilsdonk, E.P.C.1    Yancey, P.G.2    Stoudt, G.W.3
  • 32
    • 0029829903 scopus 로고    scopus 로고
    • Intracellular trafficking of cholesterol monitored with a cyclodextrin
    • Neufeld EB, Cooney AM, Pitha J, et al. Intracellular trafficking of cholesterol monitored with a cyclodextrin. J Biol Chem 1996;271:21604-13.
    • (1996) J Biol Chem , vol.271 , pp. 21604-21613
    • Neufeld, E.B.1    Cooney, A.M.2    Pitha, J.3
  • 33
    • 0030059454 scopus 로고    scopus 로고
    • Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux
    • Yancey PG, Rodrigueza WV, Kilsdonk EPC, et al. Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux. J Biol Chem 1996;271:16026-34.
    • (1996) J Biol Chem , vol.271 , pp. 16026-16034
    • Yancey, P.G.1    Rodrigueza, W.V.2    Kilsdonk, E.P.C.3
  • 34
    • 0031692336 scopus 로고    scopus 로고
    • The caveolae membrane system
    • Anderson RGW. The caveolae membrane system. Annu Rev Biochem 1998; 67:199-225.
    • (1998) Annu Rev Biochem , vol.67 , pp. 199-225
    • Anderson, R.G.W.1
  • 35
    • 0032723268 scopus 로고    scopus 로고
    • Caveolins, liquid-ordered domains, and signal transduction
    • Smart EJ, Graf GA, McNiven MA, et al. Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol 1999;19:7289-304.
    • (1999) Mol Cell Biol , vol.19 , pp. 7289-7304
    • Smart, E.J.1    Graf, G.A.2    McNiven, M.A.3
  • 36
    • 0030941001 scopus 로고    scopus 로고
    • Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins
    • Couet J, Li S, Okamoto T, Ikezu T, Lisanti MP. Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins. J Biol Chem 1997; 272:6525-33.
    • (1997) J Biol Chem , vol.272 , pp. 6525-6533
    • Couet, J.1    Li, S.2    Okamoto, T.3    Ikezu, T.4    Lisanti, M.P.5
  • 37
    • 0028012561 scopus 로고
    • Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly-expressed in leukocytes
    • Loetscher M, Geiser T, O'Reilly T , Zwahlen R, Baggiolini M, Moser B. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly-expressed in leukocytes. J Biol Chem 1994;269:232-7.
    • (1994) J Biol Chem , vol.269 , pp. 232-237
    • Loetscher, M.1    Geiser, T.2    O'Reilly, T.3    Zwahlen, R.4    Baggiolini, M.5    Moser, B.6
  • 38
    • 0024286990 scopus 로고
    • Albumin - an important extracellular antioxidant?
    • Halliwell B. Albumin - an important extracellular antioxidant? Biochem Pharmacol 1988;37:569-71.
    • (1988) Biochem Pharmacol , vol.37 , pp. 569-571
    • Halliwell, B.1
  • 39
    • 0026682803 scopus 로고
    • Fatty acid composition of normal and malignant cells and cytotoxicity of stearic, oleic and sterculic acids in vitro
    • Fermor BF, Masters JR, Wood CB, Miller J, Apostolov K, Habib NA. Fatty acid composition of normal and malignant cells and cytotoxicity of stearic, oleic and sterculic acids in vitro. Eur J Cancer 1992;28A:1143-7.
    • (1992) Eur J Cancer , vol.28 A , pp. 1143-1147
    • Fermor, B.F.1    Masters, J.R.2    Wood, C.B.3    Miller, J.4    Apostolov, K.5    Habib, N.A.6
  • 40
    • 35548983905 scopus 로고    scopus 로고
    • The role of receptors in the HIV-1 entryprocess
    • Jones R, Nelson M. The role of receptors in the HIV-1 entryprocess. Eur J Med Res 2007;12:391-6.
    • (2007) Eur J Med Res , vol.12 , pp. 391-396
    • Jones, R.1    Nelson, M.2
  • 42
    • 34249096660 scopus 로고    scopus 로고
    • The specific role of chemokines in atherosclerosis
    • Braunersreuther V, Mach F, Steffens S. The specific role of chemokines in atherosclerosis. Thromb Haemost 2007;97:714-21.
    • (2007) Thromb Haemost , vol.97 , pp. 714-721
    • Braunersreuther, V.1    Mach, F.2    Steffens, S.3
  • 43
    • 35448954048 scopus 로고    scopus 로고
    • The many roles of chemokine receptors in neurodegenerative disorders: Emerging new therapeutical strategies
    • Mines M, Ding Y, Fan GH. The many roles of chemokine receptors in neurodegenerative disorders: emerging new therapeutical strategies. Curr Med Chem 2007;14:2456-70.
    • (2007) Curr Med Chem , vol.14 , pp. 2456-2470
    • Mines, M.1    Ding, Y.2    Fan, G.H.3
  • 44
    • 0028815042 scopus 로고
    • Palmitic acid and linoleic acid metabolism in Caco-2 cells: Different triglyceride synthesis and lipoprotein secretion
    • van Greevenbroek MM, Voorhout WF, Erkelens DW, van Meer G, de Bruin TW. Palmitic acid and linoleic acid metabolism in Caco-2 cells: different triglyceride synthesis and lipoprotein secretion. J Lipid Res 1995; 36:13-24.
    • (1995) J Lipid Res , vol.36 , pp. 13-24
    • van Greevenbroek, M.M.1    Voorhout, W.F.2    Erkelens, D.W.3    van Meer, G.4    de Bruin, T.W.5
  • 45
    • 0033452587 scopus 로고    scopus 로고
    • Induction of endothelial cell chemotaxis bysphingosine 1-phosphate and stabilization of endothelial monolayer barrier function byly sophosphatidic acid, potential mediators of hematopoietic angiogenesis
    • English D, Kovala AT, Welch Z, et al. Induction of endothelial cell chemotaxis bysphingosine 1-phosphate and stabilization of endothelial monolayer barrier function byly sophosphatidic acid, potential mediators of hematopoietic angiogenesis. J Hematother Stem Cell Res 1999;8:627-34.
    • (1999) J Hematother Stem Cell Res , vol.8 , pp. 627-634
    • English, D.1    Kovala, A.T.2    Welch, Z.3
  • 47
    • 0021355340 scopus 로고
    • A method for the quantitative recoveryof protein in dilute solution in the presence of detergents and lipids
    • Wessel D, Flügge UI. A method for the quantitative recoveryof protein in dilute solution in the presence of detergents and lipids. Anal Biochem 1984; 138:141-3.
    • (1984) Anal Biochem , vol.138 , pp. 141-143
    • Wessel, D.1    Flügge, U.I.2


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