Modulation of preactivation of PPAR-β on memory and learning dysfunction and inflammatory response in the hippocampus in rats exposed to global cerebral ischemia/reperfusion

PPAR Research

Volumn , Issue , 2012, Pages

  Kuang, Ge ^a   He, Qin ^a   Zhang, Yunmei ^a   Zhuang, Ruichun ^a   Xiang, Anling ^a   Jiang, Qingsong ^a   Luo, Ying ^a   Yang, Junqing ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

[4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; NEUROPROTECTIVE AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; GLOBAL CEREBRAL ISCHEMIA REPERFUSION INJURY; HIPPOCAMPUS; LEARNING DISORDER; MALE; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

EID: 84867855955     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2012/209794     Document Type: Article

References (48)

1. Harukuni I., Bhardwaj A., Mechanisms of brain injury after global cerebral ischemia. Neurologic Clinics 2006 24 1 1 21 2-s2.0-31344438217 10.1016/j.ncl.2005.10.004
2. Collino M., Patel N. S. A., Thiemermann C., Review: PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury. Therapeutic Advances in Cardiovascular Disease 2008 2 3 179 197 2-s2.0-59649111988 10.1177/1753944708090924
3. Longstreth W. T. Jr., Dikmen S. S., Outcomes after cardiac arrest. Annals of Emergency Medicine 1993 22 1 64 69 2-s2.0-0027464218 10.1016/S0196-0644(05) 80252-5
4. Lagali P. S., Corcoran C. P., Picketts D. J., Hippocampus development and function: role of epigenetic factors and implications for cognitive disease. Clinical Genetics 2010 78 4 321 333 2-s2.0-77956415882 10.1111/j.1399-0004.2010. 01503.x
5. Pulsinelli W. A., Brierley J. B., Plum F., Temporal profile of neuronal damage in a model of transient forebrain ischemia. Annals of Neurology 1982 11 5 491 498 2-s2.0-0020067965
6. Chen J., Nagayama T., Jin K., Anne Stetler R., Zhu R. L., Graham S. H., Simon R. P., Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. Journal of Neuroscience 1998 18 13 4914 4928 2-s2.0-0032124903
7. del Zoppo G., Ginis I., Hallenbeck J. M., Iadecola C., Wang X., Feuerstein G. Z., Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia. Brain Pathology 2000 10 1 95 112 2-s2.0-0033979993
8. Allan S. M., Rothwell N. J., Cytokines and acute neurodegeneration. Nature Reviews Neuroscience 2001 2 10 734 744 2-s2.0-0035487313 10.1038/35094583
9. Iadecola C., Alexander M., Cerebral ischemia and inflammation. Current Opinion in Neurology 2001 14 1 89 94 2-s2.0-0035143182 10.1097/00019052- 200102000-00014
10. Dirnagl U., Simon R. P., Hallenbeck J. M., Ischemic tolerance and endogenous neuroprotection. Trends in Neurosciences 2003 26 5 248 254 2-s2.0-0038060334 10.1016/S0166-2236(03)00071-7
11. Zheng Z., Yenari M. A., Post-ischemic inflammation: molecular mechanisms and therapeutic implications. Neurological Research 2004 26 8 884 892 2-s2.0-10344229430 10.1179/016164104X2357
12. Li T. J., Qiu Y., Mao J. Q., Yang P. Y., Rui Y. C., Chen W. S., Protective effects of Guizhi-Fuling-capsules on rat brain ischemia/reperfusion injury. Journal of Pharmacological Sciences 2007 105 1 34 40 2-s2.0-34648832975 10.1254/jphs.FP0070450
13. Dienz O., Rincon M., The effects of IL-6 on CD4 T cell responses. Clinical Immunology 2009 130 1 27 33 2-s2.0-57149107119 10.1016/j.clim.2008.08. 018
14. Zhu Y., Saito K., Murakami Y., Asano M., Iwakura Y., Seishima M., Early increase in mRNA levels of pro-inflammatory cytokines and their interactions in the mouse hippocampus after transient global ischemia. Neuroscience Letters 2006 393 2-3 122 126 2-s2.0-29244478608 10.1016/j.neulet.2005.08.072
15. Schneider A., Martin-Villalba A., Weih F., Vogel J., Wirth T., Schwaninger M., NF- κ B is activated and promotes cell death in focal, cerebral ischemia. Nature Medicine 1999 5 5 554 559 2-s2.0-0032587072 10.1038/8432
16. Huang C. Y., Fujimura M., Noshita N., Chang Y. Y., Chan P. H., SOD1 down-regulates NF- κ B and c-Myc expression in mice after transient focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism 2001 21 2 163 173 2-s2.0-0035122043
17. Jiao L., Zhang J., Li Z., Liu H., Chen Y., Xu S., Edaravone alleviates delayed neuronal death and long-dated cognitive dysfunction of hippocampus after transient focal ischemia in Wistar rat brains. Neuroscience 2011 182 177 183 2-s2.0-79955477298 10.1016/j.neuroscience.2011.01.017
18. Clemens J. A., Stephenson D. T., Smalstig E. B., Dixon E. P., Little S. P., Global ischemia activates nuclear factor- κ B in forebrain neurons of rats. Stroke 1997 28 5 1073 1081 2-s2.0-0031005724
19. Wahli W., Peroxisome proliferator-activated receptors (PPARS): from metabolic control to epidermal wound healing. Swiss Medical Weekly 2002 132 7-8 83 91 2-s2.0-0037160785
20. Peters J. M., Gonzalez F. J., Sorting out the functional role(s) of peroxisome proliferator-activated receptor- β / δ (PPAR β / δ) in cell proliferation and cancer. Biochimica et Biophysica Acta 2009 1796 2 230 241 2-s2.0-70349177505 10.1016/j.bbcan.2009.06.002
21. Woods J. W., Tanen M., Figueroa D. J., Biswas C., Zycband E., Moller D. E., Austin C. P., Berger J. P., Localization of PPAR δ in murine central nervous system: expression in oligodendrocytes and neurons. Brain Research 2003 975 1-2 10 21 2-s2.0-0037728848 10.1016/S0006-8993(03)02515-0
22. Arsenijevic D., De Bilbao F., Plamondon J., Paradis E., Vallet P., Richard D., Langhans W., Giannakopoulos P., Increased infarct size and lack of hyperphagic response after focal cerebral ischemia in peroxisome proliferator-activated receptor β -deficient mice. Journal of Cerebral Blood Flow and Metabolism 2006 26 3 433 445 2-s2.0-33644540539 10.1038/sj.jcbfm.9600200
23. Pialat J. B., Cho T. H., Beuf O., Joye E., Moucharaffie S., Langlois J. B., Nemoz C., Janier M., Berthezene Y., Nighoghossian N., Desvergne B., Wiart M., MRI monitoring of focal cerebral ischemia in peroxisome proliferator- activated receptor (PPAR)-deficient mice. NMR in Biomedicine 2007 20 3 335 342 2-s2.0-34249724933 10.1002/nbm.1157
24. Iwashita A., Muramatsu Y., Yamazaki T., Muramoto M., Kita Y., Yamazaki S., Mihara K., Moriguchi A., Matsuoka N., Neuroprotective efficacy of the peroxisome proliferator-activated receptor δ -selective agonists in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics 2007 320 3 1087 1096 2-s2.0-33847169097 10.1124/jpet.106.115758
25. Kilgore K. S., Billin A. N., PPARbeta/delta ligands as modulators of the inflammatory response. Current Opinion in Investigational Drugs 2008 9 5 463 469
26. Grogaard B., Gerdin B., Arfors K. E., Forebrain ischemia in the rat: relation between duration of ischemia, use of adjunctive ganglionic blockade and long-term recovery. Stroke 1986 17 5 1010 1015 2-s2.0-0022483830
27. Zhuang R. C., Yang J. Q., Xiao X. H., Pan Y. Q., Zhang Y. M., Changes of PPAR β mRNA expression dinducec by global cerebral ischemia/reperfusion injury rat hippocampi. Sichuan Journal of Zoology 2008 6 1119 1122
28. Zhang J., Yang J. Q., He B. C., Zhou Q. X., Yu H. R., Tang Y., Liu B. Z., Berberine and total base from rhizoma coptis chinensis attenuate brain injury in an aluminum-induced rat model of neurodegenerative disease. Saudi Medical Journal 2009 30 6 760 766 2-s2.0-67651176124
29. Butler T. L., Kassed C. A., Sanberg P. R., Willing A. E., Pennypacker K. R., Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion. Brain Research 2002 929 2 252 260 2-s2.0-0037040519 10.1016/S0006-8993(01)03371-6
30. Bhandari U., Ansari M., Protective effect of aqueous extract of Embelia ribes Burm fruits in middle cerebral artery occlusion-induced focal cerebral ischemia in rats. Indian Journal of Pharmacology 2008 40 5 215 220 2-s2.0-57349093972 10.4103/0253-7613.44153
31. Xu X., Ye L., Ruan Q., Environmental enrichment induces synaptic structural modification after transient focal cerebral ischemia in rats. Experimental Biology and Medicine 2009 234 3 296 305 2-s2.0-63349108656 10.3181/0804-RM-128
32. Haraguchi T., Iwasaki K., Takasaki K., Uchida K., Naito T., Nogami A., Kubota K., Shindo T., Uchida N., Katsurabayashi S., Mishima K., Nishimura R., Fujiwara M., Telmisartan, a partial agonist of peroxisome proliferator-activated receptor γ improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia. Brain Research 2010 1353 125 132 2-s2.0-77956393248 10.1016/j.brainres.2010.07.017
33. Collino M., Aragno M., Mastrocola R., Gallicchio M., Rosa A. C., Dianzani C., Danni O., Thiemermann C., Fantozzi R., Modulation of the oxidative stress and inflammatory response by PPAR- γ agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. European Journal of Pharmacology 2006 530 1-2 70 80 2-s2.0-29844458758 10.1016/j.ejphar.2005.11.049
34. Eklöf B., Siesjö B. K., The effect of bilateral carotid artery ligation upon the blood flow and the energy state of the rat brain. Acta Physiologica Scandinavica 1972 86 2 155 165 2-s2.0-0015408574
35. Yin K. J., Deng Z., Hamblin M., Xiang Y., Huang H., Zhang J., Jiang X., Wang Y., Chen Y. E., Peroxisome proliferator-activated receptor δ regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury. Journal of Neuroscience 2010 30 18 6398 6408 2-s2.0-77951793925 10.1523/JNEUROSCI.0780-10.2010
36. Yin K. J., Deng Z., Hamblin M., Zhang J., Chen Y. E., Vascular PPAR δ protects against stroke-induced brain injury. Arteriosclerosis, Thrombosis, and Vascular Biology 2011 31 3 574 581 2-s2.0-79952189004 10.1161/ATVBAHA.110.221267
37. Parry-Jones A. R., Liimatainen T., Kauppinen R. A., Gröhn O. H. J., Rothwell N. J., Interleukin-1 exacerbates focal cerebral ischemia and reduces ischemic brain temperature in the rat. Magnetic Resonance in Medicine 2008 59 6 1239 1249 2-s2.0-44949102363 10.1002/mrm.21531
38. Hall M. G., Quignodon L., Desvergne B., Peroxisome proliferator-activated receptor β / δ in the brain: facts and hypothesis. PPAR Research 2008 2008 10 2-s2.0-55949111070 10.1155/2008/780452 780452
39. Spera P. A., Ellison J. A., Feuerstein G. Z., Barone F. C., IL-10 reduces rat brain injury following focal stroke. Neuroscience Letters 1998 251 3 189 192 2-s2.0-0032584685 10.1016/S0304-3940(98)00537-0
40. de Bilbao F., Arsenijevic D., Moll T., Garcia-Gabay I., Vallet P., Langhans W., Giannakopoulos P., In vivo over-expression of interleukin-10 increases resistance to focal brain ischemia in mice. Journal of Neurochemistry 2009 110 1 12 22 2-s2.0-67449110952 10.1111/j.1471-4159.2009.06098.x
41. Kim Y. J., Hwang S. Y., Oh E. S., Oh S., Han I. O., IL-1 β an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF- κ B pathways. Journal of Neuroscience Research 2006 84 5 1037 1046 2-s2.0-33749496917 10.1002/jnr.21011
42. Ortis F., Pirot P., Naamane N., Kreins A. Y., Rasschaert J., Moore F., Théâtre E., Verhaeghe C., Magnusson N. E., Chariot A., Orntoft T. F., Eizirik D. L., Induction of nuclear factor- κ B and its downstream genes by TNF- α and IL-1 β has a pro-apoptotic role in pancreatic beta cells. Diabetologia 2008 51 7 1213 1225 2-s2.0-44749083828 10.1007/s00125-008-0999-7
43. Gozal E., Ortiz L. A., Zou X., Burow M. E., Lasky J. A., Friedman M., Silica-induced apoptosis in murine macrophage: involvement of tumor necrosis factor- α and nuclear factor- κ B activation. American Journal of Respiratory Cell and Molecular Biology 2002 27 1 91 98 2-s2.0-0035983280
44. Takatsuna H., Morita S., Nagatsu T., Sawada M., Umezawa K., Inhibition of inflammatory cytokine secretion from mouse microglia cells by DHMEQ, an NF- κ B inhibitor. Biomedicine and Pharmacotherapy 2005 59 6 318 322 2-s2.0-23044509295 10.1016/j.biopha.2005.01.011
45. Hu X., Nesic-Taylor O., Qiu J., Rea H. C., Fabian R., Rassin D. K., Perez-Polo J. R., Activation of nuclear factor- κ B signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. Journal of Neurochemistry 2005 93 1 26 37 2-s2.0-16244378048 10.1111/j.1471-4159.2004.02968.x
46. Granet C., Miossec P., Combination of the pro-inflammatory cytokines IL-1, TNF- α and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF- κ B in osteoblast-like cells. Cytokine 2004 26 4 169 177 2-s2.0-2442621078 10.1016/j.cyto.2004.03.002
47. Ding G., Cheng L., Qin Q., Frontin S., Yang Q., PPAR δ modulates lipopolysaccharide-induced TNF α inflammation signaling in cultured cardiomyocytes. Journal of Molecular and Cellular Cardiology 2006 40 6 821 828 2-s2.0-33744519163 10.1016/j.yjmcc.2006.03.422
48. Berry E. B. E., Keelan J. A., Helliwell R. J. A., Stewart Gilmour R., Mitchell M. D., Nanomolar and micromolar effects of 15-deoxy-Δ12,14- prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors γ and δ and nuclear factor κ B. Molecular Pharmacology 2005 68 1 169 178 2-s2.0-22344434292 10.1124/mol.104.009449