Akt phosphorylation in human chondrocytes is regulated by p53R2 in response to mechanical stress

Osteoarthritis and Cartilage

Volumn 20, Issue 12, 2012, Pages 1603-1609

  Kawakita, K ^a   Nishiyama, T ^a   Fujishiro, T ^a   Hayashi, S ^a   Kanzaki, N ^a   Hashimoto, S ^a   Takebe, K ^a   Iwasa, K ^a   Sakata, S ^a   Nishida, K ^a   Kuroda, R ^a   Kurosaka, M ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Akt phosphorylation; Chondrocyte; Mechanotransduction; P53R2

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN POLYSULFATE; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN P53; PROTEIN P53R2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; FEMUR NECK FRACTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MECHANICAL STRESS; MECHANOTRANSDUCTION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TENSILE STRENGTH; TOTAL KNEE REPLACEMENT; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CELL CYCLE PROTEINS; CELLS, CULTURED; CHONDROCYTES; DNA REPAIR; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS, KNEE; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RIBONUCLEOTIDE REDUCTASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 84867850833     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.08.022     Document Type: Article

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