Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1

Journal of Biochemistry

Volumn 125, Issue 5, 1999, Pages 966-975

  Fujisawa, Takuo ^a   Hattori, Takako ^a   Takahashi, Kojiro ^a   Kuboki, Takuo ^a   Yamashita, Atsushi ^a   Takigawa, Masaharu ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Chondrocyte; Interleukin (IL) 1; Matrix metalloproteinase (MMP); Mechanical stress; Proteoglycan

Indexed keywords

COLLAGEN; DNA; GELATINASE A; GELATINASE B; INTERLEUKIN 1; MATRIX METALLOPROTEINASE INHIBITOR; MESSENGER RNA; PROTEIN; PROTEOGLYCAN;

ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; MECHANICAL STRESS; PROTEIN SYNTHESIS INHIBITION; PROTEOGLYCAN SYNTHESIS;

EID: 0032981665     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022376     Document Type: Article

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