메뉴 건너뛰기




Volumn 907, Issue , 2012, Pages 237-245

Humanization by CDR grafting and specificity-determining residue grafting

Author keywords

CDR grafting; Humanization; Immunogenicity; Monoclonal antibody; SDR grafting

Indexed keywords


EID: 84867838679     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-974-7_13     Document Type: Article
Times cited : (24)

References (26)
  • 1
    • 0022355587 scopus 로고
    • Human immune response to multiple injections of murine monoclonal IgG
    • Shawler DL et al (1985) Human immune response to multiple injections of murine monoclonal IgG. J Immunol 135:1530-1535
    • (1985) J Immunol , vol.135 , pp. 1530-1535
    • Shawler, D.L.1
  • 3
    • 0021716682 scopus 로고
    • Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains
    • Morrison SL et al (1984) Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc Natl Acad Sci U S A 81:6851-6855
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 6851-6855
    • Morrison, S.L.1
  • 5
    • 0022558297 scopus 로고
    • Replacing the complementarity-determining regions in a human antibody with those from a mouse
    • Jones PT et al (1986) Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321:522-525
    • (1986) Nature , vol.321 , pp. 522-525
    • Jones, P.T.1
  • 6
    • 0023911111 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann L et al (1988) Reshaping human antibodies for therapy. Nature 332:323-327
    • (1988) Nature , vol.332 , pp. 323-327
    • Riechmann, L.1
  • 7
    • 0024815233 scopus 로고
    • A humanized antibody that binds to the interleukin 2 receptor
    • Queen C et al (1989) A humanized antibody that binds to the interleukin 2 receptor. Proc Natl Acad Sci U S A 86:10029-10033
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 10029-10033
    • Queen, C.1
  • 9
    • 27144457667 scopus 로고    scopus 로고
    • Monoclonal antibody successes in the clinic
    • Reichert JM (2005) Monoclonal antibody successes in the clinic. Nat Biotechnol 23: 1073-1078
    • (2005) Nat Biotechnol , vol.23 , pp. 1073-1078
    • Reichert, J.M.1
  • 10
    • 17644378667 scopus 로고    scopus 로고
    • Immunogenicity of engineered antibodies
    • Hwang WY, Foote J (2005) Immunogenicity of engineered antibodies. Methods 36:3-10
    • (2005) Methods , vol.36 , pp. 3-10
    • Hwang, W.Y.1    Foote, J.2
  • 11
    • 0026648717 scopus 로고
    • Dissection of the combining site in a humanized anti-Tac antibody
    • Glaser SM et al (1992) Dissection of the combining site in a humanized anti-Tac antibody. J Immunol 149:2607-2614
    • (1992) J Immunol , vol.149 , pp. 2607-2614
    • Glaser, S.M.1
  • 12
    • 0028289241 scopus 로고
    • Anatomy of an antibody molecule
    • Padlan EA (1994) Anatomy of an antibody molecule. Mol Immunol 31:169-217
    • (1994) Mol Immunol , vol.31 , pp. 169-217
    • Padlan, E.A.1
  • 13
    • 0028798104 scopus 로고
    • Identi fi cation of speci fi city-determining residues in antibodies
    • Padlan EA, Abergel C, Tipper JP (1995) Identi fi cation of speci fi city-determining residues in antibodies. FASEB J 9:133-139
    • (1995) FASEB J , vol.9 , pp. 133-139
    • Padlan, E.A.1    Abergel, C.2    Tipper, J.P.3
  • 14
    • 0034142231 scopus 로고    scopus 로고
    • Structural correlates of an anticarcinoma antibody: Identi fi cation of speci fi city-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only
    • Tamura M et al (2000) Structural correlates of an anticarcinoma antibody: identi fi cation of speci fi city-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only. J Immunol 164:1432-1441
    • (2000) J Immunol , vol.164 , pp. 1432-1441
    • Tamura, M.1
  • 15
    • 0037105591 scopus 로고    scopus 로고
    • Grafting of "abbreviated" CDRs containing speci fi city determining residues (SDRs) essential for ligand contact to engineer a less immunogenic humanized mAb
    • De Pascalis R et al (2002) Grafting of "abbreviated" CDRs containing speci fi city determining residues (SDRs) essential for ligand contact to engineer a less immunogenic humanized mAb. J Immunol 169:3076-3084
    • (2002) J Immunol , vol.169 , pp. 3076-3084
    • De Pascalis, R.1
  • 16
    • 0141756310 scopus 로고    scopus 로고
    • Minimizing immunogenicity of the SDR-grafted humanized antibody CC49 by genetic manipulation of the framework residues
    • Gonzales NR et al (2003) Minimizing immunogenicity of the SDR-grafted humanized antibody CC49 by genetic manipulation of the framework residues. Mol Immunol 40:337-349
    • (2003) Mol Immunol , vol.40 , pp. 337-349
    • Gonzales, N.R.1
  • 17
    • 33646382846 scopus 로고    scopus 로고
    • Construction, af fi nity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody
    • Yoon SO et al (2006) Construction, af fi nity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody. J Biol Chem 281:6985-6992
    • (2006) J Biol Chem , vol.281 , pp. 6985-6992
    • Yoon, S.O.1
  • 18
    • 77952744667 scopus 로고    scopus 로고
    • Construction of a humanized antibody to hepatitis B surface antigen by speci fi city determining residues (SDR)-grafting and de-immunization
    • Kim K-S, Myung P-K, Hong HJ (2010) Construction of a humanized antibody to hepatitis B surface antigen by speci fi city determining residues (SDR)-grafting and de-immunization. Biochem Biophys Res Commun 396:231-237
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 231-237
    • Kim, K.-S.1    Myung, P.-K.2    Hong, H.J.3
  • 19
    • 34547207674 scopus 로고    scopus 로고
    • Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lidopening mechanism
    • Chi S-W et al (2007) Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lidopening mechanism. Proc Natl Acad Sci U S A 104:9230-9235
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9230-9235
    • Chi, S.-W.1
  • 20
    • 0037107598 scopus 로고    scopus 로고
    • Surface plasmon resonance-based competition assay to assess the sera reactivity of variants of humanized antibodies
    • Gonzales NR et al (2002) Surface plasmon resonance-based competition assay to assess the sera reactivity of variants of humanized antibodies. J Immunol Methods 268:197-210
    • (2002) J Immunol Methods , vol.268 , pp. 197-210
    • Gonzales, N.R.1
  • 21
    • 0027253021 scopus 로고
    • Optimal humanization of 1B4, an anti-CD18 murine monoclonal antibody, is achieved by correct choice of human V-region framework sequences
    • Singer II et al (1993) Optimal humanization of 1B4, an anti-CD18 murine monoclonal antibody, is achieved by correct choice of human V-region framework sequences. J Immunol 150:2844-2857
    • (1993) J Immunol , vol.150 , pp. 2844-2857
    • Singer, I.I.1
  • 22
    • 9544258383 scopus 로고    scopus 로고
    • A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab
    • Rosok MJ et al (1996) A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab. J Biol Chem 271: 22611-22618
    • (1996) J Biol Chem , vol.271 , pp. 22611-22618
    • Rosok, M.J.1
  • 23
    • 0034121814 scopus 로고    scopus 로고
    • Design and synthesis of germline-based hemi-humanized single chain Fv against the CD18 surface antigen
    • Caldas C et al (2000) Design and synthesis of germline-based hemi-humanized single chain Fv against the CD18 surface antigen. Protein Eng 13:353-360
    • (2000) Protein Eng , vol.13 , pp. 353-360
    • Caldas, C.1
  • 24
    • 0028935437 scopus 로고
    • Identi fi cation of framework residues required to restore antigen binding during reshaping of a monoclonal antibody against the glycoprotein gB of human cytomegalovirus
    • Tempest PR et al (1995) Identi fi cation of framework residues required to restore antigen binding during reshaping of a monoclonal antibody against the glycoprotein gB of human cytomegalovirus. Int J Biol Macromol 17:37-42
    • (1995) Int J Biol Macromol , vol.17 , pp. 37-42
    • Tempest, P.R.1
  • 26
    • 1642389424 scopus 로고    scopus 로고
    • Kinetic exclusion assays to study high-af fi nity binding interactions in homogenous solutions
    • Benny KCLo (ed) . Humana, Totowa, NJ
    • Blake RC II, Blake DA (2004) Kinetic exclusion assays to study high-af fi nity binding interactions in homogenous solutions. In: Benny KCLo (ed) Antibody engineering: methods and protocols, methods in molecular biology, vol 248. Humana, Totowa, NJ, pp 417-430
    • (2004) Antibody Engineering: Methods and Protocols, Methods in Molecular Biology , vol.248 , pp. 417-430
    • Blake, R.C.I.I.1    Blake, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.