A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab

Journal of Biological Chemistry

Volumn 271, Issue 37, 1996, Pages 22611-22618

  Rosok, Mae Joanne ^a,c   Yelton, Dale E ^a   Harris, Linda J ^a   Bajorath, Jürgen ^a   Hellström, Karl Erik ^a   Hellström, Ingegerd ^a   Cruz, Gina A ^b,d   Kristensson, Karin ^b   Lin, Huey ^b   Huse, William D ^b   Glaser, Scott M ^b,c  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^b Ixsys Inc   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

^d Desmos Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; IMMUNE RESPONSE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; BASE SEQUENCE; BINDING SITES; DRUG DESIGN; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; LEWIS BLOOD-GROUP SYSTEM; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TEMPLATES, GENETIC;

MURINAE;

EID: 9544258383     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.37.22611     Document Type: Article

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