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Volumn 109, Issue 4, 2012, Pages 1023-1028

Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders

Author keywords

Gene regulation; Plasminogen activator inhibitor 1; Small molecule

Indexed keywords

6 CHLORO 8 NICOTINAMIDO BETA CARBOLINE; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; POLYAMIDE; RNA; SYNAPTOTAGMIN I;

EID: 84856387590     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118506109     Document Type: Article
Times cited : (112)

References (35)
  • 1
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140:883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 2
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao YX, Greten FR, Li ZW (2002) NF-kappa B in cancer: From innocent bystander to major culprit. Nat Rev Cancer 2:301-310. (Pubitemid 37328783)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.-W.4
  • 3
    • 58149090925 scopus 로고    scopus 로고
    • SIRT6 links histone H3 lysine 9 deacetylation to NF-kappa B-dependent gene expression and organismal life span
    • Kawahara TLA, et al. (2009) SIRT6 links histone H3 lysine 9 deacetylation to NF-kappa B-dependent gene expression and organismal life span. Cell 136:62-74.
    • (2009) Cell , vol.136 , pp. 62-74
    • Kawahara, T.L.A.1
  • 4
    • 0022481133 scopus 로고
    • Multiple nuclear factors interact with the immunoglobulin enhancer sequences
    • Sen R, Baltimore D (1986) Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705-716. (Pubitemid 16020062)
    • (1986) Cell , vol.46 , Issue.5 , pp. 705-716
    • Sen, R.1    Baltimore, D.2
  • 5
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappa B: Players, pathways, perspectives
    • Gilmore TD (2006) Introduction to NF-kappa B: Players, pathways, perspectives. Oncogene 25:6680-6684.
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 6
    • 33750446341 scopus 로고    scopus 로고
    • Inhibitors of NF-kappaB signaling: 785 and counting
    • DOI 10.1038/sj.onc.1209982, PII 1209982
    • Gilmore TD, Herscovitch M (2006) Inhibitors of NF-kappa B signaling: 785 and counting. Oncogene 25:6887-6899. (Pubitemid 44657858)
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6887-6899
    • Gilmore, T.D.1    Herscovitch, M.2
  • 7
    • 0037832279 scopus 로고    scopus 로고
    • Recognition of the DNA minor groove by pyrrole-imidazole polyamides
    • DOI 10.1016/S0959-440X(03)00081-2
    • Dervan PB, Edelson BS (2003) Recognition of the DNA minor groove by pyrroleimidazole polyamides. Curr Opin Struct Biol 13:284-299. (Pubitemid 36782454)
    • (2003) Current Opinion in Structural Biology , vol.13 , Issue.3 , pp. 284-299
    • Dervan, P.B.1    Edelson, B.S.2
  • 10
    • 0032576722 scopus 로고    scopus 로고
    • Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands
    • DOI 10.1038/35106
    • White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB (1998) Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature 391:468-471. (Pubitemid 28086542)
    • (1998) Nature , vol.391 , Issue.6666 , pp. 468-471
    • White, S.1    Szewczyk, J.W.2    Turner, J.M.3    Baird, E.E.4    Dervan, P.B.5
  • 11
    • 69449087887 scopus 로고    scopus 로고
    • Allosteric modulation of DNA by small molecules
    • Chenoweth DM, Dervan PB (2009) Allosteric modulation of DNA by small molecules. Proc Natl Acad Sci USA 106:13175-13179.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13175-13179
    • Chenoweth, D.M.1    Dervan, P.B.2
  • 13
    • 34548581017 scopus 로고    scopus 로고
    • Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface
    • DOI 10.1021/cb700110z
    • Nickols NG, Jacobs CS, Farkas ME, Dervan PB (2007) Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface. ACS Chem Biol 2:561-571. (Pubitemid 350011327)
    • (2007) ACS Chemical Biology , vol.2 , Issue.8 , pp. 561-571
    • Nickols, N.G.1    Jacobs, C.S.2    Farkas, M.E.3    Dervan, P.B.4
  • 15
    • 70349731736 scopus 로고    scopus 로고
    • Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression
    • Muzikar KA, Nickols NG, Dervan PB (2009) Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression. Proc Natl Acad Sci USA 106:16598-16603.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16598-16603
    • Muzikar, K.A.1    Nickols, N.G.2    Dervan, P.B.3
  • 16
    • 0037129975 scopus 로고    scopus 로고
    • Inhibition of DNA binding by NF-kappaB with pyrrole-imidazole polyamides
    • DOI 10.1021/bi020114i
    • Wurtz NR, Pomerantz JL, Baltimore D, Dervan PB (2002) Inhibition of DNA binding by NF-κB with pyrrole-imidazole polyamides. Biochemistry 41:7604-7609. (Pubitemid 34627787)
    • (2002) Biochemistry , vol.41 , Issue.24 , pp. 7604-7609
    • Wurtz, N.R.1    Pomerantz, J.L.2    Baltimore, D.3    Dervan, P.B.4
  • 17
    • 33845341473 scopus 로고    scopus 로고
    • Programmable oligomers targeting 5′-GGGG-3′ in the minor groove of DNA and NF-kappaB binding inhibition
    • DOI 10.1016/j.bmc.2006.10.051, PII S0968089606008832
    • Chenoweth DM, Poposki JA, Marques MA, Dervan PB (2007) Programmable oligomers targeting 5′-GGGG-3′ in the minor groove of DNA and NF-κB binding inhibition. Bioorg Med Chem 15:759-770. (Pubitemid 44880726)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.2 , pp. 759-770
    • Chenoweth, D.M.1    Poposki, J.A.2    Marques, M.A.3    Dervan, P.B.4
  • 18
    • 78650264127 scopus 로고    scopus 로고
    • Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factorbeta 1 promoter
    • Matsuda H, et al. (2011) Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factorbeta 1 promoter. Kidney Int 79:46-56.
    • (2011) Kidney Int , vol.79 , pp. 46-56
    • Matsuda, H.1
  • 19
    • 77950833803 scopus 로고    scopus 로고
    • Variation in transcription factor binding among humans
    • Kasowski M, et al. (2010) Variation in transcription factor binding among humans. Science 328:232-235.
    • (2010) Science , vol.328 , pp. 232-235
    • Kasowski, M.1
  • 20
    • 0031035634 scopus 로고    scopus 로고
    • The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression
    • Kannabiran C, Zeng X, Vales LD (1997) The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression. Mol Cell Biol 17:1-9. (Pubitemid 26425588)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.1 , pp. 1-9
    • Kannabiran, C.1    Zeng, X.2    Vales, L.D.3
  • 21
    • 0028308257 scopus 로고
    • Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6
    • Kunsch C, Lang RK, Rosen CA, Shannon MF (1994) Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6. J Immunol 153:153-164.
    • (1994) J Immunol , vol.153 , pp. 153-164
    • Kunsch, C.1    Lang, R.K.2    Rosen, C.A.3    Shannon, M.F.4
  • 23
    • 53049104824 scopus 로고    scopus 로고
    • TLR-4, IL-1R and TNF-R signaling to NF-kappa B: Variations on a common theme
    • Verstrepen L, et al. (2008) TLR-4, IL-1R and TNF-R signaling to NF-kappa B: Variations on a common theme. Cell Mol Life Sci 65:2964-2978.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2964-2978
    • Verstrepen, L.1
  • 24
    • 0032556894 scopus 로고    scopus 로고
    • Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA
    • Chen FE, Huang DB, Chen YQ, Ghosh G (1998) Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA. Nature 391:410-413.
    • (1998) Nature , vol.391 , pp. 410-413
    • Chen, F.E.1    Huang, D.B.2    Chen, Y.Q.3    Ghosh, G.4
  • 25
    • 68149139538 scopus 로고    scopus 로고
    • The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
    • Vereecke L, Beyaert R, van Loo G (2009) The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology. Trends Immunol 30:383-391.
    • (2009) Trends Immunol , vol.30 , pp. 383-391
    • Vereecke, L.1    Beyaert, R.2    Van Loo, G.3
  • 26
    • 77954391573 scopus 로고    scopus 로고
    • Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
    • Vereecke L, et al. (2010) Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J Exp Med 207:1513-1523.
    • (2010) J Exp Med , vol.207 , pp. 1513-1523
    • Vereecke, L.1
  • 27
    • 0023130521 scopus 로고
    • Plasminogen-activator inhibitors
    • Sprengers ED, Kluft C (1987) Plasminogen-activator inhibitors. Blood 69:381-387.
    • (1987) Blood , vol.69 , pp. 381-387
    • Sprengers, E.D.1    Kluft, C.2
  • 28
    • 0028901713 scopus 로고
    • Allele-specific increase in basal transcription of the plasminogen-activator inhibitor-1 gene is associated with myocardial infarction
    • Eriksson P, Kallin B, Vanthooft FM, Bavenholm P, Hamsten A (1995) Allele-specific increase in basal transcription of the plasminogen-activator inhibitor-1 gene is associated with myocardial infarction. Proc Natl Acad Sci USA 92:1851-1855.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1851-1855
    • Eriksson, P.1    Kallin, B.2    Vanthooft, F.M.3    Bavenholm, P.4    Hamsten, A.5
  • 29
    • 0026650622 scopus 로고
    • Increased type-1 plasminogen-activator inhibitor gene expression in atherosclerotic human arteries
    • Schneiderman J, et al. (1992) Increased type-1 plasminogen-activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci USA 89:6998-7002.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6998-7002
    • Schneiderman, J.1
  • 30
    • 84856380669 scopus 로고    scopus 로고
    • http://www.nf-kb.org/.
  • 31
    • 0036280321 scopus 로고    scopus 로고
    • Solid-phase synthesis of DNA binding polyamides on oxime resin
    • DOI 10.1016/S0968-0896(02)00133-5, PII S0968089602001335
    • Belitsky JM, Nguyen DH, Wurtz NR, Dervan PB (2002) Solid-phase synthesis of DNA binding polyamides on oxime resin. Bioorg Med Chem 10:2767-2774. (Pubitemid 34626240)
    • (2002) Bioorganic and Medicinal Chemistry , vol.10 , Issue.8 , pp. 2767-2774
    • Belitsky, J.M.1    Nguyen, D.H.2    Wurtz, N.R.3    Dervan, P.B.4
  • 32
    • 33846937087 scopus 로고    scopus 로고
    • Improved nuclear localization of DNA-binding polyamides
    • DOI 10.1093/nar/gkl1042
    • Nickols NG, Jacobs CS, Farkas ME, Dervan PB (2007) Improved nuclear localization of DNA-binding polyamides. Nucl Acids Res 35:363-370. (Pubitemid 46237387)
    • (2007) Nucleic Acids Research , vol.35 , Issue.2 , pp. 363-370
    • Nickols, N.G.1    Jacobs, C.S.2    Farkas, M.E.3    Dervan, P.B.4
  • 34
    • 33644873467 scopus 로고    scopus 로고
    • Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation
    • Nowak DE, Tian B, Brasier AR (2005) Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation. BioTechniques 39:715-725.
    • (2005) BioTechniques , vol.39 , pp. 715-725
    • Nowak, D.E.1    Tian, B.2    Brasier, A.R.3
  • 35
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28:511-515.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1


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