Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36341-36355

  Ramani, Komal ^a   Tomasi, Maria Lauda ^a   Yang, Heping ^a,b   Ko, Kwangsuk ^a   Lu, Shelly C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT RESPONSE ELEMENTS; BILE DUCTS; BINDING ACTIVITIES; CATALYTIC SUBUNITS; FIBROGENESIS; GLUTAMATE-CYSTEINE LIGASE; HEPATIC STELLATE CELLS; HETERODIMERIZATION; HETERODIMERS; IN-VIVO; LIVER INJURIES; NUCLEAR LEVELS; PROTECTIVE EFFECTS; QUIESCENT STATE; S-ADENOSYLMETHIONINE; SUMOYLATION; SYNTHASES; SYNTHETIC ENZYMES; URSODEOXYCHOLIC ACID;

BIOMOLECULES; BODY FLUIDS;

AMINO ACIDS;

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BILIRUBIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR MAFG; TRANSCRIPTION FACTOR NRF2;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BILIRUBIN BLOOD LEVEL; CELL ACTIVATION; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DENSITOMETRY; DIMERIZATION; FIBROGENESIS; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LIVER INJURY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STELLATE CELL; SUMOYLATION; TRANSCRIPTION INITIATION SITE;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; GLUTAMATE-CYSTEINE LIGASE; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MAFG TRANSCRIPTION FACTOR; MOLECULAR SEQUENCE DATA; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; RESPONSE ELEMENTS; S-ADENOSYLMETHIONINE; SUMO-1 PROTEIN; SUMOYLATION; URSODEOXYCHOLIC ACID;

EID: 84867801009     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.370775     Document Type: Article

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