Novel bio-active lipid nanocarriers for the stabilization and sustained release of sitosterol

Nanotechnology

Volumn 23, Issue 45, 2012, Pages

  Lacatusu, I ^a,b   Badea, N ^a   Stan, R ^a   Meghea, A ^a  

^a UNIVERSITY POLITEHNICA OF BUCHAREST   (Romania)

^b PETROLEUM GAS UNIVERSITY OF PLOIESTI   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE INGREDIENTS; ANTIOXIDANT ACTIVITIES; ANTIOXIDANT PROPERTIES; BIO-ACTIVE; CHAIN REACTION; CRYSTALLINE LATTICE; ELECTROKINETIC POTENTIALS; ENTRAPMENT EFFICIENCY; FISH OIL; FOOD GRADE; FUNCTIONAL FOODS; GRAPE SEED OIL; GREEN TEA EXTRACTS; IN-VITRO; NANO-EMULSIONS; NANOCARRIERS; NATURAL OIL; PHYSICAL STABILITY; RELEASE PROPERTY; SPHERICAL MORPHOLOGIES; SUSTAINED RELEASE;

FREE RADICALS; FRUITS; SURFACE ACTIVE AGENTS; ZETA POTENTIAL;

OILS AND FATS;

ANTIOXIDANT; CLIONASTEROL; FOOD ADDITIVE; GAMMA-SITOSTEROL; LIPID; NANOMATERIAL; OIL; PLANT EXTRACT; SITOSTEROL DERIVATIVE; SURFACTANT;

ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; TEA; ULTRASTRUCTURE;

ANTIOXIDANTS; DELAYED-ACTION PREPARATIONS; FOOD ADDITIVES; LIPIDS; NANOSTRUCTURES; OILS; PLANT EXTRACTS; SITOSTEROLS; SURFACE-ACTIVE AGENTS; TEA;

EID: 84867799224     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/23/45/455702     Document Type: Article

References (34)

1. Chaudhry Q, Scotter M, Blackburn J, Ross B, Boxall A, Castle L, Aitken R and Watkins R 2008 Applications and implications of nanotechnologies for the food sector Food Addit. Contam. 25 241-58
2. Cushen M, Kerry J, Morris M, Cruz-Romero M and Cummins E 2012 Nanotechnologies in the food industry - recent developments, risks and regulation Trends Food Sci. Technol. 24 30-46
3. Lin C C, Lin H Y, Chen H C, Yu M W and Lee M H 2009 Stability and characterisation of phospholipid - based curcumin - encapsulated microemulsions Food Chem. 116 923-8
4. Sansukcharearnpon A, Wanichwecharungruang S, Leepipatpaiboonb N, Kerdcharoen T and Arayachukeat S 2010 High loading fragrance encapsulation based on a polymer-blend: preparation and release behavior Int. J. Pharm. 391 267-73
5. Garti N, Spernath A, Aserin A and Lutz R 2005 Nano-sized self-assemblies of nonionic surfactants as solubilization reservoirs and microreactors for food systems Soft Matter 1 206-18 (Pubitemid 41411308)
6. Amar-Yuli I, Libster D, Aserin A and Garti N 2009 Solubilization of food bioactives within lyotropic liquid crystalline mesophases Curr. Opin. Colloid Interface Sci. 14 21-32
7. Mozafari M R, Flanagan J, Matia-Merino L, Awati A, Omri A, Suntres Z E and Singh H 2006 Recent trends in the lipid-based nanoencapsulation of antioxidants and their role in foods J. Sci. Food Agricult. 86 2038-45 (Pubitemid 44544804)
8. Bouwmeester H, Dekkers S, Maryvon N Y, Hagens W I, Bulder A S, de Heer C, Ten Voorde S E C G, Winjnhoven S W P, Marvin H J P and Sips J A M 2009 Review of health safety aspects of nanotechnologies in food production Regul. Toxicol. Pharmacol. 53 52-62
9. Zhang D, Tan T and Gao L 2006 Preparation of oridonin-loaded solid lipid nanoparticles and studies on them in vitro and in vivo Nanotechnology 17 5821 (Pubitemid 46069957)
10. Borgogna M, Bellich B, Zorzin L, Lapasin R and Cesàro A 2009 Food microencapsulation of bioactive coumponds: rheological and thermal characterisation of non-conventional gelling systems Food Chem. 122 416-23
11. Ajilla C M, Anaidu K, Bhat S G and Prasada Rao U J S 2007 Bioactive compounds and antioxidant potential of mango peel extract Food Chem. 105 982-8 (Pubitemid 47069735)
12. Biesalski H-K, Dragsted L O, Elmadfa I, Grossklaus R, Müller M, Schrenk D, Walter P and Weber P 2009 Bioactive compounds: definition and assessment of activity J. Nutrition 25 1202-5
13. Chen H, Weiss J and Shahidi F 2006 Nanotechnology in nutraceuticals and functional foods Food Technol. 60 30-6
14. Porter C J H, Pouton C W, Cuine J F and Charman W N 2008 Enhancing intestinal drug solubilisation using lipid-based delivery system Adv. Drug Deliv. Rev. 60 673-91
15. Weiss J, Decker E A, McClements D J, Kristbergsson K, Helgason T and Awad T 2008 Solid lipid nanoparticles as delivery systems for bioactive food components Food Biophys. 3 146-54
16. Souto E B and Müller R H 2006 Application of lipid nanoparticles (SLN and NLC) in food industry J. Food Technol. 4 90-5
17. McClements D J, Decker E A, Park Y and Weiss J 2009 Structural design principles for delivery of bioactive components in nutraceuticals and functional foods Crit. Rev. Food Sci. Nutr. 49 577-606
18. Fathi M, Mozafari M R and Mohebbi M 2012 Nanoencapsulation of food ingredients using lipid based delivery systems Trends Food Sci. Technol. 23 13-27
19. Triplett M D and Rathman J F 2009 Optimization of β-carotene loaded solid lipid nanoparticles preparation using a high shear homogenization technique J. Nanopart. Res. 11 601-14
20. Trombino S, Cassano R, Muzzalupo R, Pingitore A, Cioneb E and Picci N 2009 Stearyl ferulate-based solid lipid nanoparticles for the encapsulation and stabilization of β-carotene and α-tocopherol Colloids Surf. B 72 181-7
21. Liu C H and Wu C T 2010 Optimization of nanostructured lipid carriers for lutein delivery Colloids Surf. A 353 149-56
22. Paolino D, Stancampiano A H S, Cilurzo F, Cosco D, Puglisi G and Pignatello R 2011 Nanostructured lipid carriers (NLC) for the topical delivery of lutein Drug Deliv. Lett. 1 32-9
23. Baskar A A, Ignacimuthu S, Paulraj G M and Numair K S 2010 Chemopreventive potential of β-sitosterol in experimental colon cancer model - an in vitro and in vivo study BMC Complement. Alter. Med. 10 24
24. Moghadasian M H and Frohlich J J 1999 Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis: clinical and experimental evidence Am. J. Med. 107 588-94
25. Awad A B, Chinnam M, Fink C S and Bradford P G 2007 β-sitosterol activates Fas signaling in human breast cancer cells Phytomedicine 14 747-54 (Pubitemid 47539097)
26. Awad A B, Andrew T B and Carol S F 2005 Effect of resveratrol and β-sitosterol in combination on reactive oxygen species and prostaglandin release by PC-3 cells Prostaglandins Leukot. Essent. Fatty Acids 72 219-26 (Pubitemid 40139087)
27. Jayaprakash G K, Mandadi K K, Poulose S M, Jadegoud Y, Nagana G G A and Patil B S 2007 Inhibition of colon cancer cell growth and antioxidant activity of bioactive compounds from Poncirus trifoliata (L.) Raf Bioorg. Med. Chem. 14 4923-32 (Pubitemid 46836831)
28. Leifert W R and Abeywardena M Y 2008 Cardioprotective actions of grape polyphenols Nutr. Res. 28 729-37
29. Reddy L H and Couvreur P 2009 Squalene: a natural triterpene for use in disease management and therapy Adv. Drug Deliv. Rev. 61 1412-26
30. Lacatusu I, Badea N, Oprea O, Bojin D and Meghea A 2012 Highly antioxidant carotene-lipid nanocarriers: synthesis and antibacterial activity J. Nanopart. Res. 14 902-18
31. Niculae G, Lacatusu I, Badea N and Meghea A 2012 Lipid nanoparticles based on butyl-methoxydibenzoylmethane: in vitro UVA blocking effect Nanotechnology 23 315704
32. Helgason T, Awad T S, Kristbergsson K, McClements D J and Weiss J 2009 Effect of surfactant surface coverage on formation of solid lipid nanoparticles (SLN) J. Colloid Interface Sci. 334 75-81
33. Fang J Y, Fang C L, Liu C H and Su Y H 2008 Lipid nanoparticles as vehicles for topical psoralen delivery. Solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC) Eur. J. Pharm. Biopharm. 70 633-40
34. Johnson I T, Williamson G and Musk S R 1994 Anticarcinogenic factors in plant foods: a new class of nutrients Nutr. Rev. 7 175-204