Nano-formulation of paclitaxel by vitamin E succinate functionalized pluronic micelles for enhanced encapsulation, stability and cytotoxicity

Colloids and Surfaces B: Biointerfaces

Volumn 102, Issue , 2013, Pages 604-610

  Tao, Youhua ^a,b   Han, Jianfeng ^a,b   Wang, Xiaowen ^a,b,c   Dou, Huanyu ^a,b  

^a Texas Tech University Health Sciences Center El Paso   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c WEIFANG MEDICAL UNIVERSITY   (China)

Author keywords

Drug delivery; Paclitaxel; Pluronic micelles; Stability; Vitamin E succinate

Indexed keywords

ANTI-TUMORS; ANTICANCER ACTIVITIES; AVERAGE SIZE; CELLULAR UPTAKE; CHEMOTHERAPEUTIC DRUGS; CYTOTOXICITY ASSAYS; ELIMINATION RATE; ENCAPSULATION EFFICIENCY; FUNCTIONALIZED; IN-VIVO; PACLITAXEL; PHARMACOKINETIC STUDIES; PLURONIC MICELLES; SYSTEMIC CIRCULATION; VITAMIN-E;

CONVERGENCE OF NUMERICAL METHODS; DRUG DELIVERY; ENCAPSULATION; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

MICELLES;

ALPHA TOCOPHEROL SUCCINATE; PACLITAXEL; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG ELIMINATION; DRUG FORMULATION; DRUG STABILITY; GLIOMA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER; MICELLE; MOUSE; NANOENCAPSULATION; NANOFORMULATION; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DRUG CARRIERS; DRUG STABILITY; HUMANS; MICE; MICELLES; PACLITAXEL; SUCCINIC ACID; VITAMIN E;

TOSCANA VIRUS;

EID: 84867799211     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.08.062     Document Type: Article

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