Folate-functionalized unimolecular micelles based on a degradable amphiphilic dendrimer-like star polymer for cancer cell-targeted drug delivery

Biomacromolecules

Volumn 12, Issue 7, 2011, Pages 2697-2707

  Cao, Weiqiang ^a   Zhou, Jing ^a   Mann, Alexander ^a   Wang, Yong ^a   Zhu, Lei ^a,b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b Case Western Reserve University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHILICS; ANTICANCER DRUG; CELLULAR BINDING; CELLULAR CYTOTOXICITY; CONFOCAL MICROSCOPES; DEGRADATION MECHANISM; DENDRONS; DOXORUBICIN; DRUG MOLECULES; FOLATE-FUNCTIONALIZED; GAIN INSIGHT; HYDROLYTIC DEGRADATION; HYDROPHILIC SHELL; HYDROPHOBIC CORE; HYDROPHOBIC INTERACTIONS; IN-VITRO; MEAN PARTICLE SIZE; NANO SCALE; NANO-SIZE; NANOCARRIERS; PH-DEPENDENT; POLY-L-LACTIDE; PROPIONIC ACIDS; PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIMILAR DEGREE; STAR POLYMERS; SUSTAINED RELEASE; TARGETED DRUG DELIVERY; UNIMOLECULAR MICELLES; WEIGHT LOSS;

BIOCOMPATIBILITY; CELLS; DEGRADATION; DENDRIMERS; DISEASES; DRUG DELIVERY; DRUG INTERACTIONS; FATTY ACIDS; FLOW CYTOMETRY; FUNCTIONAL POLYMERS; HYDROPHILICITY; HYDROPHOBICITY; LIGHT TRANSMISSION; METHANOL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RESONANCE; STARS; TRANSMISSION ELECTRON MICROSCOPY;

MICELLES;

DOXORUBICIN; FOLATE FUNCTIONALIZED DEGRADABLE AMPHIPHILIC DENDRIMER LIKE STAR POLYMER; FOLATE RECEPTOR; NANOCARRIER; POLYESTER; POLYLACTIDE; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; BIOCOMPATIBILITY; CANCER CELL; CELL STRAIN KB; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; LIGHT SCATTERING; NANOENCAPSULATION; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SUSTAINED DRUG RELEASE; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DENDRIMERS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FOLIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; KB CELLS; MICELLES; MOLECULAR STRUCTURE; NANOSTRUCTURES; PARTICLE SIZE; POLYMERS; SURFACE PROPERTIES;

EID: 79960258209     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm200487h     Document Type: Article

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