Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling

Journal of Neuroscience

Volumn 32, Issue 43, 2012, Pages 14966-14978

  Arons, Magali H ^a   Thynne, Charlotte J ^b   Grabrucker, Andreas M ^a,c   Li, Dong ^b   Schoen, Michael ^c   Cheyne, Juliette E ^b   Boeckers, Tobias M ^c   Montgomery, Johanna M ^b   Garner, Craig C ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; INTEGRIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE CELL ADHESION MOLECULE; NEUREXIN; NEUROLIGIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN HOMER 1; PROTEIN PROSAP2; PROTEIN SHANK3; SCAFFOLD PROTEIN; SYNAPSIN; SYNAPTOBREVIN 2; SYNAPTOPHYSIN; TUBULIN; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; AUTISM; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE MUTATION; GENETIC TRANSFECTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; WESTERN BLOTTING;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANALYSIS OF VARIANCE; ANIMALS; CADHERINS; CARRIER PROTEINS; CELL ADHESION MOLECULES, NEURONAL; CELLS, CULTURED; DIZOCILPINE MALEATE; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HUMANS; MALE; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; POST-SYNAPTIC DENSITY; PYRIDINIUM COMPOUNDS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; TRANSFECTION; VESICULAR GLUTAMATE TRANSPORT PROTEIN 1;

EID: 84867796651     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2215-12.2012     Document Type: Article

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