ProSAP/Shank proteins - A family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

Journal of Neurochemistry

Volumn 81, Issue 5, 2002, Pages 903-910

  Boeckers, Tobias M ^a   Bockmann, Jürgen ^a   Kreutz, Michael R ^b   Gundelfinger, Eckart D ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Cytoskeleton; Glutamate receptors; Neurological disorders; Postsynaptic density; Synapse

Indexed keywords

GLUTAMATE RECEPTOR; MEMBRANE PROTEIN; METABOTROPIC RECEPTOR; SHANK PROTEIN; UNCLASSIFIED DRUG;

CYTOSKELETON; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUROLOGIC DISEASE; NEUROTRANSMITTER RELEASE; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FAMILY; RECEPTOR DENSITY; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; TISSUE DISTRIBUTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CYTOSKELETAL PROTEINS; HUMANS; NERVE TISSUE PROTEINS; NERVOUS SYSTEM DISEASES; RECEPTORS, GLUTAMATE; SYNAPSES;

EID: 0036316727     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00931.x     Document Type: Review

References (45)

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2. Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family
3. Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin
4. Disruption of the ProSAP2 gene in a t (12; 22) (q24.1; q13.3) is associated with the 22q13.3 deletion syndrome
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14. Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95
15. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity
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17. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules
18. The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins
19. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit
20. Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development
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32. Protein synthesis at synaptic sites on dendrites
33. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density
34. The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family
35. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors
36. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
37. Laminar organization of the NMDA receptor complex within the postsynaptic density
38. Marking synaptic activity in dendritic spines with a calpain substrate exhibiting fluorescence resonance energy transfer
39. A familiar pericentric inversion of chromosome 22 with a recombinant subject illustrating a 'pure' partial monosomy syndrome
40. Molecular characterization of a 130-Kb terminal microdeletion at 22q in a child with mild mental retardation
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