Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways

Journal of Pineal Research

Volumn 53, Issue 4, 2012, Pages 390-398

  Bähr, Ina ^a   Mühlbauer, Eckhard ^b   Albrecht, Elke ^a   Peschke, Elmar ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b Saxon Academy of Sciences   (Germany)

Author keywords

glucagon; glucose metabolism; melatonin; MT1 and MT2 receptor; pancreatic cell; type 2 diabetes

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; GLUCAGON; GLUCAGON RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LUZINDOLE; MELATONIN; MELATONIN RECEPTOR; MESSENGER RNA; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; GLUCAGON BLOOD LEVEL; GLUCAGON RELEASE; IN VITRO STUDY; IN VIVO STUDY; ISOLATED PANCREAS ISLET; KNOCKOUT MOUSE; MALE; MOUSE; NEWBORN; NONHUMAN; PANCREAS ISLET ALPHA CELL; RAT; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; CELL LINE; CYCLIC AMP; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCAGON; GLUCAGON-SECRETING CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; LIVER; MALE; MELANINS; MICE; MICE, KNOCKOUT; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3-KINASE; RATS; RATS, WISTAR; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RECEPTORS, GLUCAGON; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRAHYDRONAPHTHALENES; TISSUE CULTURE TECHNIQUES; TRYPTAMINES; TYPE C PHOSPHOLIPASES;

EID: 84867741975     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2012.01009.x     Document Type: Article

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