Impairment of diastolic function by lack of frequency-dependent myofilament desensitization in rabbit right ventricular hypertrophy

Circulation: Heart Failure

Volumn 2, Issue 5, 2009, Pages 472-481

  Varian, Kenneth D ^a   Kijtawornrat, Anusak ^b   Gupta, Subash C ^a   Torres, Carlos A A ^a   Monasky, Michelle M ^a   Hiranandani, Nitisha ^a   Delfin, Dawn A ^a   Rafael Fortney, Jill A ^a   Periasamy, Muthu ^a   Hamlin, Robert L ^b   Janssen, Paul M L ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Calcium sensitivity; EC coupling; Heart rate; Hypertrophy; Myofilaments

Indexed keywords

CALCIUM; FURA 2; PHOSPHOPROTEIN; TROPONIN I; ACTIN; ATRIAL NATRIURETIC FACTOR; CALCIUM BINDING PROTEIN; CARDIAC MYOSIN; CARRIER PROTEIN; MYOSIN BINDING PROTEIN C; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 2; MYOSIN-BINDING PROTEIN C; PHOSPHOLAMBAN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; TROPONIN T;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DIASTOLIC DYSFUNCTION; FREQUENCY MODULATION; HEART RIGHT VENTRICLE HYPERTROPHY; LUNG ARTERY BANDING; MALE; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RABBIT; SHAM PROCEDURE; WESTERN BLOTTING; ANIMAL; CALCIUM SIGNALING; DIASTOLE; DISEASE MODEL; HEART CONTRACTION; HEART PACING; HEART RIGHT VENTRICLE FUNCTION; METABOLISM; MICROFILAMENT; MUSCLE STRENGTH; PATHOPHYSIOLOGY; PHOSPHORYLATION;

ACTINS; ANIMALS; ATRIAL NATRIURETIC FACTOR; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CARDIAC MYOSINS; CARDIAC PACING, ARTIFICIAL; CARRIER PROTEINS; DIASTOLE; DISEASE MODELS, ANIMAL; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MICROFILAMENTS; MUSCLE STRENGTH; MYOCARDIAL CONTRACTION; MYOSIN LIGHT CHAINS; PHOSPHORYLATION; RABBITS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SODIUM-CALCIUM EXCHANGER; TROPONIN I; TROPONIN T; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 70350468587     PISSN: 19413289     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.109.853200     Document Type: Article

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