Nifedipine inhibits cardiac hypertrophy and left ventricular dysfunction in response to pressure overload

Journal of Cardiovascular Translational Research

Volumn 3, Issue 4, 2010, Pages 304-313

  Ago, Tetsuro ^a   Yang, Yanfei ^a   Zhai, Peiyong ^a   Sadoshima, Junichi ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Ca2+ Antagonists; Calcium Calmodulin Kinase; Cardiac Hypertrophy; Heart Failure; NFAT; Nifedipine; Pressure Overload

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; HISTONE DEACETYLASE 4; NIFEDIPINE; PHENYLEPHRINE; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GENE EXPRESSION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; TREATMENT DURATION;

ALGORITHMS; ANIMALS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMEGALY; DISEASE MODELS, ANIMAL; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; NIFEDIPINE; SIGNAL TRANSDUCTION; STROKE VOLUME; VENTRICULAR DYSFUNCTION, LEFT;

MUS;

EID: 77955519404     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-010-9182-x     Document Type: Article

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