Water-soluble andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways

International Immunopharmacology

Volumn 14, Issue 4, 2012, Pages 613-619

  Guo, Wenjie ^a   Liu, Wen ^a   Chen, Gong ^a   Hong, Shaocheng ^a   Qian, Cheng ^a   Xie, Ning ^b   Yang, Xiaoling ^b   Sun, Yang ^a   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

^b Jiangxi Qingfeng Pharmaceutical Company Ltd   (China)

Author keywords

Andrographolide; Inflammation; NF B; Sepsis; Sulfonate

Indexed keywords

AMINOTRANSFERASE; ANDROGRAPHOLIDE; ANDROGRAPHOLIDE SULFONATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT3 PROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XI YAN PING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTISEPSIS; ARTICLE; DOWN REGULATION; ENZYME ACTIVITY; LIVER INJURY; LUNG INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; SULFONATION;

ANIMALS; CYTOKINES; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LIVER DISEASES; MICE; MICE, INBRED BALB C; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, MESSENGER; SACROILIITIS; SEPSIS; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS;

EID: 84867651811     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.09.002     Document Type: Article

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