A combination of 2-deoxy-d-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells

Tumor Biology

Volumn 33, Issue 4, 2012, Pages 1021-1030

  Bhardwaj, Richa ^a   Sharma, Pradeep K ^a,b   Jadon, S P S ^c   Varshney, Rajeev ^a,d  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^b GURU GOBIND SINGH INDRAPRASTHA UNIVERSITY   (India)

^c Shri Varshneya College   (India)

^d DRDO   (India)

Author keywords

2 deoxy D glucose; 6 aminonicotinamide; G2 Marrest; Oxidative stress; Radiosensitization

Indexed keywords

6 AMINONICOTINAMIDE; CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DEOXYGLUCOSE; REACTIVE OXYGEN METABOLITE; CDC2 PROTEIN, HUMAN; CYCLIN B;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; HUMAN; HUMAN CELL; LUNG CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIOSENSITIZATION; SQUAMOUS CELL CARCINOMA; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DIVISION; CELL LINE; CELL PROLIFERATION; CHEMORADIOTHERAPY; METABOLISM; NEOPLASM; PATHOLOGY; RADIATION EXPOSURE; TUMOR CELL LINE; WESTERN BLOTTING;

6-AMINONICOTINAMIDE; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL DIVISION; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHEMORADIOTHERAPY; CYCLIN A; CYCLIN B; DEOXYGLUCOSE; FLOW CYTOMETRY; G2 PHASE; HUMANS; NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 84867604591     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-012-0335-1     Document Type: Article

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