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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 21, 2012, Pages 6540-6548

How hydrogen bonds impact P-glycoprotein transport and permeability

(3) Desai, Prashant V a Raub, Thomas J a Blanco, Maria Jesus a

a ELI LILLY AND COMPANY (United States)

Author keywords

ATP binding cassette; HBA; HBD; Hydrogen bond; Intramolecular hydrogen bond; P Glycoprotein; Permeability; TPSA

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN;

ANIMAL CELL; BINDING AFFINITY; HYDROGEN BOND; LIPID MEMBRANE; MEMBRANE PERMEABILITY; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN INTERACTION; PROTEIN TRANSPORT; REVIEW; THERMODYNAMICS;

BIOLOGICAL TRANSPORT; HYDROGEN BONDING; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; PERMEABILITY;

EID: 84867577372 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.08.059 Document Type: Review

Times cited : (113)

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