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Volumn 64, Issue 11, 2012, Pages 1638-1645

Effect of multidose cilostazol on pharmacokinetic and lipid profile of atorvastatin in male Wistar rats

Author keywords

atorvastatin; cilostazol; lipid profile; pharmacokinetic and pharmacodynamic interaction

Indexed keywords

ATORVASTATIN; CHOLESTEROL; CILOSTAZOL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84867577328     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01542.x     Document Type: Article
Times cited : (5)

References (38)
  • 1
    • 84875240548 scopus 로고    scopus 로고
    • HIV drug-drug interactions. New York State Department of Health AIDS Institute accessed on 8 April 2012
    • HIV drug-drug interactions. New York State Department of Health AIDS Institute. http://www.hivguidelines.org/wp-content/uploads/a-hiv-drug-drug- interactions-04-14-2010.pdf accessed on 8 April 2012.
  • 2
    • 33644692006 scopus 로고    scopus 로고
    • Scientific perspectives on drug transporters and their role in drug interactions
    • Zhang L, et al,. Scientific perspectives on drug transporters and their role in drug interactions. Mol Pharm 2006; 3: 62-69.
    • (2006) Mol Pharm , vol.3 , pp. 62-69
    • Zhang, L.1
  • 3
    • 1442319158 scopus 로고    scopus 로고
    • The pharmacology of cilostazol
    • Schrör K,. The pharmacology of cilostazol. Diabetes Obes Metab 2002; 4: S14-S19.
    • (2002) Diabetes Obes Metab , vol.4
    • Schrör, K.1
  • 4
    • 80355125146 scopus 로고    scopus 로고
    • Novel agents for anti-platelet therapy
    • Ji X, Hou M,. Novel agents for anti-platelet therapy. J Hematol Oncol 2011; 4: 44.
    • (2011) J Hematol Oncol , vol.4 , pp. 44
    • Ji, X.1    Hou, M.2
  • 5
    • 0035942767 scopus 로고    scopus 로고
    • Medical treatment of peripheral arterial disease and claudication
    • Hiatt WR,. Medical treatment of peripheral arterial disease and claudication. N Engl J Med 2001; 344: 1608-1621.
    • (2001) N Engl J Med , vol.344 , pp. 1608-1621
    • Hiatt, W.R.1
  • 6
    • 79960912304 scopus 로고    scopus 로고
    • Phosphodiesterases as targets for intermittent claudication
    • Liu Y, et al,. Phosphodiesterases as targets for intermittent claudication. Handb Exp Pharmacol 2011; 204: 211-236.
    • (2011) Handb Exp Pharmacol , vol.204 , pp. 211-236
    • Liu, Y.1
  • 7
    • 0037603310 scopus 로고    scopus 로고
    • Cilostazol: A review of its use in intermittent claudication
    • Chapman TM, Goa KL,. Cilostazol: a review of its use in intermittent claudication. Am J Cardiovasc Drugs 2003; 3: 117-138.
    • (2003) Am J Cardiovasc Drugs , vol.3 , pp. 117-138
    • Chapman, T.M.1    Goa, K.L.2
  • 8
    • 0031649108 scopus 로고    scopus 로고
    • Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication
    • Elam MB, et al,. Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication. Arterioscler Thromb Vasc Biol 1998; 18: 1942-1947.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1942-1947
    • Elam, M.B.1
  • 9
    • 0034092579 scopus 로고    scopus 로고
    • In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms
    • Abbas R, et al,. In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms. Hum Exp Toxicol 2000; 19: 178-184.
    • (2000) Hum Exp Toxicol , vol.19 , pp. 178-184
    • Abbas, R.1
  • 10
    • 0021836693 scopus 로고
    • The absorption, distribution and excretion of a new antithrombotic and vasodilating agent, cilostazol, in rat, rabbit, dog and man
    • Akiyama H, et al,. The absorption, distribution and excretion of a new antithrombotic and vasodilating agent, cilostazol, in rat, rabbit, dog and man. Arzneimittelforschung 1985; 35: 1124-1132.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1124-1132
    • Akiyama, H.1
  • 11
    • 0242290406 scopus 로고    scopus 로고
    • Limited influence of P-glycoprotein on small-intestinal absorption of cilostazol, a high absorptive permeability drug
    • Toyobuku H, et al,. Limited influence of P-glycoprotein on small-intestinal absorption of cilostazol, a high absorptive permeability drug. J Pharm Sci 2003; 92: 2249-2259.
    • (2003) J Pharm Sci , vol.92 , pp. 2249-2259
    • Toyobuku, H.1
  • 12
    • 0036291921 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors
    • Williams D, Feely J,. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin Pharmacokinet 2002; 41: 343-370.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 343-370
    • Williams, D.1    Feely, J.2
  • 13
    • 33845666551 scopus 로고    scopus 로고
    • Safety and statins: Pharmacologic and clinical perspectives
    • Bottorff MB,. Safety and statins: pharmacologic and clinical perspectives. Prev Med Manag Care 2004; 4: S30-S37.
    • (2004) Prev Med Manag Care , vol.4
    • Bottorff, M.B.1
  • 14
    • 0001349572 scopus 로고    scopus 로고
    • Absolute bioavailability or atorvastatin in man
    • Gibson DM, et al,. Absolute bioavailability or atorvastatin in man. Pharm Res 1997; 14: S253.
    • (1997) Pharm Res , vol.14
    • Gibson, D.M.1
  • 15
    • 33745230031 scopus 로고    scopus 로고
    • Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: Relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism
    • Lau YY, et al,. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism. Drug Metab Dispos 2006; 34: 1175-1181.
    • (2006) Drug Metab Dispos , vol.34 , pp. 1175-1181
    • Lau, Y.Y.1
  • 16
    • 0242383181 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of atorvastatin
    • Lennernas H,. Clinical pharmacokinetics of atorvastatin. Clin Pharmacokinet 2003; 42: 1141-1160.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 1141-1160
    • Lennernas, H.1
  • 17
    • 0038701977 scopus 로고    scopus 로고
    • Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients
    • Lins RL, et al,. Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients. Nephrol Dial Transplant 2003; 18: 967-976.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 967-976
    • Lins, R.L.1
  • 18
    • 0032791745 scopus 로고    scopus 로고
    • Metabolism and excretion of atorvastatin between rats and dogs
    • Black AE, et al,. Metabolism and excretion of atorvastatin between rats and dogs. Drug Metab Dispos 1999; 27: 916-923.
    • (1999) Drug Metab Dispos , vol.27 , pp. 916-923
    • Black, A.E.1
  • 19
    • 0000460810 scopus 로고    scopus 로고
    • Metabolism and excretion of [14C]-atorvastatin in patients with T-tube drainage
    • Le Couteur DG, et al,. Metabolism and excretion of [14C]-atorvastatin in patients with T-tube drainage. Proc Aust Soc Clin Exp Pharmacol Toxicol 1996; 3: 153.
    • (1996) Proc Aust Soc Clin Exp Pharmacol Toxicol , vol.3 , pp. 153
    • Le Couteur, D.G.1
  • 20
    • 0036233667 scopus 로고    scopus 로고
    • Glucuronidation of statins in animals and humans: A novel mechanism of statin lactonization
    • Prueksaritanont T, et al,. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos 2002; 30: 505-512.
    • (2002) Drug Metab Dispos , vol.30 , pp. 505-512
    • Prueksaritanont, T.1
  • 21
    • 16244396867 scopus 로고    scopus 로고
    • Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin
    • Hochman JH, et al,. Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin. Pharm Res 2004; 21: 1686-1691.
    • (2004) Pharm Res , vol.21 , pp. 1686-1691
    • Hochman, J.H.1
  • 22
    • 0033678688 scopus 로고    scopus 로고
    • Atorvastatin co-administration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion
    • Boyd RA, et al,. Atorvastatin co-administration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion. J Clin Pharmacol 2000; 40: 91-98.
    • (2000) J Clin Pharmacol , vol.40 , pp. 91-98
    • Boyd, R.A.1
  • 23
    • 0031847115 scopus 로고    scopus 로고
    • Effect of itraconazole on the pharmacokinetics of atorvastatin
    • Kantola T, et al,. Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 1998; 64: 58-65.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 58-65
    • Kantola, T.1
  • 24
    • 0032806143 scopus 로고    scopus 로고
    • Erythromycin co-administration increases plasma atorvastatin concentrations
    • Siedlik PH, et al,. Erythromycin co-administration increases plasma atorvastatin concentrations. J Clin Pharmacol 1999; 39: 501-504.
    • (1999) J Clin Pharmacol , vol.39 , pp. 501-504
    • Siedlik, P.H.1
  • 25
    • 0242645646 scopus 로고    scopus 로고
    • Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
    • Lilja JJ, et al,. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999; 66: 118-127.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 118-127
    • Lilja, J.J.1
  • 26
    • 0033503514 scopus 로고    scopus 로고
    • Effect of multiple cilostazol doses on single dose lovastatin pharmacokinetics in healthy volunteers
    • Bramer SL, et al,. Effect of multiple cilostazol doses on single dose lovastatin pharmacokinetics in healthy volunteers. Clin Pharmacokinet 1999; 37: 69-77.
    • (1999) Clin Pharmacokinet , vol.37 , pp. 69-77
    • Bramer, S.L.1
  • 27
    • 0015349346 scopus 로고
    • Cholesterol 7α-hydroxylase in rat liver microsomal preparations
    • Mitropoulos KA, Balasubramaniam S,. Cholesterol 7α-hydroxylase in rat liver microsomal preparations. Biochem J 1972; 128: 1-9.
    • (1972) Biochem J , vol.128 , pp. 1-9
    • Mitropoulos, K.A.1    Balasubramaniam, S.2
  • 28
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • Smith PK, et al,. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150: 76-85.
    • (1985) Anal Biochem , vol.150 , pp. 76-85
    • Smith, P.K.1
  • 29
    • 0035671940 scopus 로고    scopus 로고
    • In vitro and in vivo assessment of cellular permeability and pharmacodynamics of S-nitrosylated captopril, a nitric oxide donor
    • Jia L, Wong H,. In vitro and in vivo assessment of cellular permeability and pharmacodynamics of S-nitrosylated captopril, a nitric oxide donor. Br J Pharmacol 2001; 134: 1697-1704.
    • (2001) Br J Pharmacol , vol.134 , pp. 1697-1704
    • Jia, L.1    Wong, H.2
  • 30
    • 34250009276 scopus 로고    scopus 로고
    • Development and validation of atorvastatin by LC-ESI-MS and application in bioequivalence research in healthy Chinese volunteers
    • Ma L, et al,. Development and validation of atorvastatin by LC-ESI-MS and application in bioequivalence research in healthy Chinese volunteers. Chromatographia 2007; 65: 737-741.
    • (2007) Chromatographia , vol.65 , pp. 737-741
    • Ma, L.1
  • 31
    • 0010037510 scopus 로고    scopus 로고
    • Food and Drug Administration (FDA). Rockvile: U.S. Department of Health and Human Services
    • Food and Drug Administration (FDA). Guidance for Industry: Bio Analytical Method Validation. Rockvile: U.S. Department of Health and Human Services, 2001.
    • (2001) Guidance for Industry: Bio Analytical Method Validation
  • 32
    • 0030005053 scopus 로고    scopus 로고
    • Effect of age and gender on pharmacokinetics of atorvastatin in humans
    • Gibson DM, et al,. Effect of age and gender on pharmacokinetics of atorvastatin in humans. J Clin Pharmacol 1996; 36: 242-246.
    • (1996) J Clin Pharmacol , vol.36 , pp. 242-246
    • Gibson, D.M.1
  • 33
    • 0033679135 scopus 로고    scopus 로고
    • Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase
    • Whitfield LR, et al,. Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase. Eur J Drug Metab Pharmacokinet 2000; 25: 97-101.
    • (2000) Eur J Drug Metab Pharmacokinet , vol.25 , pp. 97-101
    • Whitfield, L.R.1
  • 34
    • 0033783036 scopus 로고    scopus 로고
    • Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-coA reductase inhibitor atorvastatin
    • Jacobsen W, et al,. Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-coA reductase inhibitor atorvastatin. Drug Metab Dispos 2000; 28: 1369-1378.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1369-1378
    • Jacobsen, W.1
  • 35
    • 0141569628 scopus 로고    scopus 로고
    • Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily m RNAS in small intestine
    • Takara K, et al,. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily m RNAS in small intestine. Drug Metab Dispos 2003; 31: 1235-1239.
    • (2003) Drug Metab Dispos , vol.31 , pp. 1235-1239
    • Takara, K.1
  • 36
    • 84867332395 scopus 로고    scopus 로고
    • Effect of grapefruit juice and ritonavir on pharmacokinetics of lopinavir in wistar rats
    • doi: 10.1002/ptr.4593. [Epub ahead of print]
    • Ravi PR, et al,. Effect of grapefruit juice and ritonavir on pharmacokinetics of lopinavir in wistar rats. Phytother Res 2012. doi: 10.1002/ptr.4593. [Epub ahead of print].
    • (2012) Phytother Res
    • Ravi, P.R.1
  • 37
    • 28044457103 scopus 로고    scopus 로고
    • Functional interactions between P-glycoprotein and CYP3A in drug metabolism
    • Christians U, et al,. Functional interactions between P-glycoprotein and CYP3A in drug metabolism. Expert Opin Drug Metab Toxicol 2005; 1: 641-654.
    • (2005) Expert Opin Drug Metab Toxicol , vol.1 , pp. 641-654
    • Christians, U.1
  • 38
    • 78649684484 scopus 로고    scopus 로고
    • A Microwave induced solubility enhancement of poorly water soluble atorvastatin calcium
    • Maurya D, et al,. A Microwave induced solubility enhancement of poorly water soluble atorvastatin calcium. J Pharm Pharmacol 2010; 62: 1599-1606.
    • (2010) J Pharm Pharmacol , vol.62 , pp. 1599-1606
    • Maurya, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.