Age and estrogen-based hormone therapy affect systemic and local IL-6 and IGF-1 pathways in women

Age

Volumn 34, Issue 5, 2012, Pages 1249-1260

  Ahtiainen, Maarit ^a   Pöllänen, Eija ^a   Ronkainen, Paula H A ^a   Alen, Markku ^b   Puolakka, Jukka ^c   Kaprio, Jaakko ^d   Sipilä, Sarianna ^a   Kovanen, Vuokko ^a  

^a UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c Central Finland Central Hospital   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Aging; Estrogen based hormone therapy; IGF 1; IL 6; Inflammation; Skeletal muscle

Indexed keywords

ESTROGEN; GLYCOPROTEIN GP 130; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ABDOMINAL FAT; ADULT; AGE; ARTICLE; BODY COMPOSITION; BODY FAT; CATABOLISM; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENETIC VARIABILITY; HORMONE SUBSTITUTION; HUMAN; HUMAN TISSUE; IGF 1R GENE; IGF1EA GENE; IGF1EC GENE; IGFBP3 GENE; IGFBP5 GENE; IRS1 GENE; IRS2 GENE; LEUKOCYTE; MOLECULAR MECHANICS; MONOZYGOTIC TWINS; MUSCLE BIOPSY; POSTMENOPAUSE; PREMENOPAUSE; PROTEIN BLOOD LEVEL; PROTEIN PROTEIN INTERACTION; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VASTUS LATERALIS MUSCLE;

ADIPOSE TISSUE; ADULT; AGING; ESTROGEN REPLACEMENT THERAPY; FEMALE; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; LEUKOCYTES; MIDDLE AGED; MUSCLE, SKELETAL; POLYMERASE CHAIN REACTION; RECEPTOR, IGF TYPE 1; RNA;

EID: 84867574877     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9298-1     Document Type: Article

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