PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice

Brain Research

Volumn 1483, Issue , 2012, Pages 89-95

  Santhanam, Anantha Vijay R ^a,b   D'uscio, Livius V ^a,b   He, Tongrong ^a,b   Katusic, Zvonimir S ^a,b  

^a Mayo Clinic College of Medicine   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Antioxidant; Cerebral microvessel; eNOS uncoupling; GTP cyclohydrolase I; Nitric oxide

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; CATALASE; CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRITE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SUPEROXIDE; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; BIOAVAILABILITY; BLOOD CELL COUNT; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; MALE; MICROVASCULATURE; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BIOPTERIN; BLOOD PRESSURE; CEREBRAL CORTEX; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GTP CYCLOHYDROLASE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MICROVESSELS; MUTATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE III; POLYCOMB REPRESSIVE COMPLEX 1; PPAR DELTA; SUPEROXIDES; THIAZOLES;

MUS;

EID: 84867574313     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.09.012     Document Type: Article

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