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Volumn 73, Issue 6, 1999, Pages 2563-2568

Stimulation of the brain NO/cyclic GMP pathway by peripheral administration of tetrahydrobiopterin in the hph-1 mouse

Author keywords

Cyclic GMP; Dopa responsive dystonia; GTP cyclohydrolase deficiency; hph 1 mouse; Nitric oxide synthase; Tetrahydrobiopterin

Indexed keywords

CYCLIC GMP; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN;

EID: 0032727867     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0732563.x     Document Type: Article
Times cited : (19)

References (38)
  • 1
    • 0032584999 scopus 로고    scopus 로고
    • Increased inducible nitric oxide synthase protein but limited nitric oxide formation occurs in astrocytes of the hph-1 (tetrahydrobiopterin deficient) mouse
    • Barker J. E., Strangward H. M., Brand M. P., Hurst R. D., Land J. M., Clark J. B., and Heales S. J. (1998) Increased inducible nitric oxide synthase protein but limited nitric oxide formation occurs in astrocytes of the hph-1 (tetrahydrobiopterin deficient) mouse. Brain Res. 804, 1-6.
    • (1998) Brain Res. , vol.804 , pp. 1-6
    • Barker, J.E.1    Strangward, H.M.2    Brand, M.P.3    Hurst, R.D.4    Land, J.M.5    Clark, J.B.6    Heales, S.J.7
  • 2
    • 0002756708 scopus 로고
    • Tetrahydrobiopterin deficiency: From phenotype to genotype
    • Blau N., Thöni B., Heizmann C. W., and Dhondt J.-L. (1993) Tetrahydrobiopterin deficiency: from phenotype to genotype. Pteridines 4, 1-10.
    • (1993) Pteridines , vol.4 , pp. 1-10
    • Blau, N.1    Thöni, B.2    Heizmann, C.W.3    Dhondt, J.-L.4
  • 3
    • 0028897734 scopus 로고
    • Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph-1 mouse
    • Brand M. P., Heales S. J., Land J. M., and Clark J. B. (1995) Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph-1 mouse. J. Inherit. Metab. Dis. 18, 33-39.
    • (1995) J. Inherit. Metab. Dis. , vol.18 , pp. 33-39
    • Brand, M.P.1    Heales, S.J.2    Land, J.M.3    Clark, J.B.4
  • 4
    • 0030606932 scopus 로고    scopus 로고
    • Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse
    • Brand M. P., Briddon A., Land J. M., Clark J. B., and Heales S. J. R. (1996a) Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse. Brain Res. 735, 169-172.
    • (1996) Brain Res. , vol.735 , pp. 169-172
    • Brand, M.P.1    Briddon, A.2    Land, J.M.3    Clark, J.B.4    Heales, S.J.R.5
  • 5
    • 0030023052 scopus 로고    scopus 로고
    • Neurochemical effects following peripheral administration of tetrahydropterin derivatives to the hph-1 mouse
    • Brand M. P., Hyland K., Engle T., Smith I., and Heales S. J. R. (1996b) Neurochemical effects following peripheral administration of tetrahydropterin derivatives to the hph-1 mouse. J. Neurochem. 66, 1150-1156.
    • (1996) J. Neurochem. , vol.66 , pp. 1150-1156
    • Brand, M.P.1    Hyland, K.2    Engle, T.3    Smith, I.4    Heales, S.J.R.5
  • 6
    • 0022480610 scopus 로고
    • DOPA-sensitive progressive dystonia of childhood with fluctuations of symptoms - Segawa's syndrome and possible variants. Results of a collaborative study of the european federation of child neurology societies (EFCNS)
    • Deonna T. (1986) DOPA-sensitive progressive dystonia of childhood with fluctuations of symptoms - Segawa's syndrome and possible variants. Results of a collaborative study of the European Federation of Child Neurology Societies (EFCNS). Neuropediatrics 17, 81-85.
    • (1986) Neuropediatrics , vol.17 , pp. 81-85
    • Deonna, T.1
  • 7
    • 84889196867 scopus 로고
    • Therapy of tetrahydrobiopterin deficiencies
    • (Bickel H. and Wachtel U., eds), Thieme, Stuttgart
    • Endres W. (1985) Therapy of tetrahydrobiopterin deficiencies, in Inherited Diseases of Amino Acid Metabolism (Bickel H. and Wachtel U., eds), pp. 124-132. Thieme, Stuttgart.
    • (1985) Inherited Diseases of Amino Acid Metabolism , pp. 124-132
    • Endres, W.1
  • 8
    • 0024419119 scopus 로고
    • Tetrahydrobiopterin administration in biopterin-deficient progressive dystonia with diurnal variation
    • Fink J. K., Ravin P., Argoff C. E., Levine R. A., Brady R. O., Hallett M., and Barton N. W. (1989) Tetrahydrobiopterin administration in biopterin-deficient progressive dystonia with diurnal variation. Neurology 39, 1393-1395.
    • (1989) Neurology , vol.39 , pp. 1393-1395
    • Fink, J.K.1    Ravin, P.2    Argoff, C.E.3    Levine, R.A.4    Brady, R.O.5    Hallett, M.6    Barton, N.W.7
  • 12
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signalling in the nervous system
    • Garthwaite J. (1991) Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14, 60-67.
    • (1991) Trends Neurosci. , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 13
    • 0028917372 scopus 로고
    • Nitric oxide signaling in the central nervous system
    • Garthwaite J. and Boulton C. L. (1995) Nitric oxide signaling in the central nervous system. Annu. Rev. Physiol. 57, 683-706.
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 683-706
    • Garthwaite, J.1    Boulton, C.L.2
  • 16
    • 0022460861 scopus 로고
    • Estimation of tetrahydrobiopterin and other pterins in cerebrospinal fluid using reversed-phase high-performance liquid chromatography with electrochemical and fluorescence detection
    • Howells D. W., Smith I., and Hyland K. (1986) Estimation of tetrahydrobiopterin and other pterins in cerebrospinal fluid using reversed-phase high-performance liquid chromatography with electrochemical and fluorescence detection. J. Chromatogr. 381, 285-294.
    • (1986) J. Chromatogr. , vol.381 , pp. 285-294
    • Howells, D.W.1    Smith, I.2    Hyland, K.3
  • 17
    • 0027156904 scopus 로고
    • Cerebrospinal fluid concentrations of pterins and metabolites of serotonin and dopamine in a pediatric reference population
    • Hyland K., Surtees R. A., Heales S. J., Bowron A., Howells D. W., and Smith I. (1993) Cerebrospinal fluid concentrations of pterins and metabolites of serotonin and dopamine in a pediatric reference population. Pediatr. Res. 34, 10-14.
    • (1993) Pediatr. Res. , vol.34 , pp. 10-14
    • Hyland, K.1    Surtees, R.A.2    Heales, S.J.3    Bowron, A.4    Howells, D.W.5    Smith, I.6
  • 18
    • 0030056511 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and biogenic amine metabolism in the hph-1 mouse
    • Hyland K., Gunasekera R. S., Engle T., and Arnold L. A. (1996) Tetrahydrobiopterin and biogenic amine metabolism in the hph-1 mouse. J. Neurochem. 67, 752-759.
    • (1996) J. Neurochem. , vol.67 , pp. 752-759
    • Hyland, K.1    Gunasekera, R.S.2    Engle, T.3    Arnold, L.A.4
  • 19
    • 0025042832 scopus 로고
    • Haem-dependent activation of guanylate cyclase and cyclic GMP formation by endogenous nitric oxide: A unique transduction mechanism for transcellular signaling
    • Ignarro L. J. (1990) Haem-dependent activation of guanylate cyclase and cyclic GMP formation by endogenous nitric oxide: a unique transduction mechanism for transcellular signaling. Pharmacol. Toxicol. 67, 1-7.
    • (1990) Pharmacol. Toxicol. , vol.67 , pp. 1-7
    • Ignarro, L.J.1
  • 20
    • 0019421457 scopus 로고
    • Peripherally administered reduced pterins do enter the brain
    • Kapatos G. and Kaufman S. (1981) Peripherally administered reduced pterins do enter the brain. Science 212, 955-956.
    • (1981) Science , vol.212 , pp. 955-956
    • Kapatos, G.1    Kaufman, S.2
  • 21
    • 0018028550 scopus 로고
    • Establishment of tetrahydrobiopterin as the hydroxylase cofactor and a review of some recent studies in man
    • Kaufman S. (1978) Establishment of tetrahydrobiopterin as the hydroxylase cofactor and a review of some recent studies in man. Psychopharmacol. Bull. 14, 38-40.
    • (1978) Psychopharmacol. Bull. , vol.14 , pp. 38-40
    • Kaufman, S.1
  • 22
    • 0019964391 scopus 로고
    • Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: Evidence that peripherally administered tetrahydropterins enter the brain
    • Kaufman S., Kapatos G., McInnes R. R., Schulman J. D., and Rizzo W. B. (1982) Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: evidence that peripherally administered tetrahydropterins enter the brain. Pediatrics 70, 376-380.
    • (1982) Pediatrics , vol.70 , pp. 376-380
    • Kaufman, S.1    Kapatos, G.2    McInnes, R.R.3    Schulman, J.D.4    Rizzo, W.B.5
  • 23
    • 0028302095 scopus 로고
    • The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain
    • Klatt P., Schmid M., Leopold E., Schmidt K., Werner E. R., and Mayer B. (1994) The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain. J. Biol. Chem. 269, 13861-13866.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13861-13866
    • Klatt, P.1    Schmid, M.2    Leopold, E.3    Schmidt, K.4    Werner, E.R.5    Mayer, B.6
  • 24
    • 0022345297 scopus 로고
    • Decreased cerebellar 3′,5′-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt)
    • Lorden J. F., Oltmans G. A., McKeon T. W., Lutes J., and Beales M. (1985) Decreased cerebellar 3′,5′-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt). J. Neurosci. 5, 2618-2625.
    • (1985) J. Neurosci. , vol.5 , pp. 2618-2625
    • Lorden, J.F.1    Oltmans, G.A.2    McKeon, T.W.3    Lutes, J.4    Beales, M.5
  • 26
    • 0029437498 scopus 로고
    • Why tetrahydrobiopterin?
    • Mayer B. and Werner E. R. (1995) Why tetrahydrobiopterin? Adv. Pharmacol. 34, 251-261.
    • (1995) Adv. Pharmacol. , vol.34 , pp. 251-261
    • Mayer, B.1    Werner, E.R.2
  • 27
    • 0023881310 scopus 로고
    • Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity
    • McDonald J. D., Cotton R. G., Jennings I., Ledley F. D., Woo S. L., and Bode V. C. (1988) Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity. J. Neurochem. 50, 655-657.
    • (1988) J. Neurochem. , vol.50 , pp. 655-657
    • McDonald, J.D.1    Cotton, R.G.2    Jennings, I.3    Ledley, F.D.4    Woo, S.L.5    Bode, V.C.6
  • 29
    • 0022596053 scopus 로고
    • Tetrahydrobiopterin administration to rhesus macaques. Its appearance in CSF and effect on neurotransmitter synthesis
    • Miller L., Insel T., Scheinin M., Aloi J., Murphy D. L., Linnoila M., and Lovenberg W. (1986) Tetrahydrobiopterin administration to rhesus macaques. Its appearance in CSF and effect on neurotransmitter synthesis. Neurochem. Res. 11, 291-298.
    • (1986) Neurochem. Res. , vol.11 , pp. 291-298
    • Miller, L.1    Insel, T.2    Scheinin, M.3    Aloi, J.4    Murphy, D.L.5    Linnoila, M.6    Lovenberg, W.7
  • 30
    • 0020047254 scopus 로고
    • Atypical phenylketonuria with defective biopterin metabolism. Monotherapy with tetrahydrobiopterin or sepiapterin, screening and study of biosynthesis in man
    • Niederwieser A., Curtius H. C., Wang M., and Leupold D. (1982) Atypical phenylketonuria with defective biopterin metabolism. Monotherapy with tetrahydrobiopterin or sepiapterin, screening and study of biosynthesis in man. Eur. J. Pediatr. 138, 110-112.
    • (1982) Eur. J. Pediatr. , vol.138 , pp. 110-112
    • Niederwieser, A.1    Curtius, H.C.2    Wang, M.3    Leupold, D.4
  • 31
    • 0021344054 scopus 로고
    • GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia
    • Niederwieser A., Blau N., Wang M., Joller P., Atares M., and Cardesa-Garcia J. (1984) GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia. Eur. J. Pediatr. 141, 208-214.
    • (1984) Eur. J. Pediatr. , vol.141 , pp. 208-214
    • Niederwieser, A.1    Blau, N.2    Wang, M.3    Joller, P.4    Atares, M.5    Cardesa-Garcia, J.6
  • 34
    • 0032926746 scopus 로고    scopus 로고
    • GTP cyclohydrolase I gene expression in the brains of male and female hph-1 mice
    • Shimoji M., Hirayama K., Hyland K., and Kapatos G. (1999) GTP cyclohydrolase I gene expression in the brains of male and female hph-1 mice. J. Neurochem. 72, 757-764.
    • (1999) J. Neurochem. , vol.72 , pp. 757-764
    • Shimoji, M.1    Hirayama, K.2    Hyland, K.3    Kapatos, G.4
  • 37
    • 0024388901 scopus 로고
    • Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor
    • Tayeh M. A. and Marietta M. A. (1989) Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor. J. Biol. Chem. 264, 19654-19658.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19654-19658
    • Tayeh, M.A.1    Marietta, M.A.2
  • 38
    • 84889228056 scopus 로고    scopus 로고
    • Simple linear correlation
    • Prentice Hall, Upper Saddle River, New Jersey
    • Zar J. H. (1996) Simple linear correlation, in Biostatistical Analysis, 3rd edit., pp. 371-406. Prentice Hall, Upper Saddle River, New Jersey.
    • (1996) Biostatistical Analysis, 3rd Edit. , pp. 371-406
    • Zar, J.H.1


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