A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression

EMBO Journal

Volumn 31, Issue 20, 2012, Pages 4035-4044

  Langemeier, Jörg ^a   Schrom, Eva Maria ^b   Rabner, Alona ^c   Radtke, Maximilian ^a   Zychlinski, Daniela ^a   Saborowski, Anna ^a,d   Bohn, Georg ^a,e   Mandel Gutfreund, Yael ^c   Bodem, Jochen ^b   Klein, Christoph ^a,f   Bohne, Jens ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

30 UTR mutation; polyadenylation; U1 site

Indexed keywords

HISTONE; MESSENGER RNA; POLYADENYLIC ACID; SMALL NUCLEAR RIBONUCLEOPROTEIN;

3' UNTRANSLATED REGION; ARTICLE; BIOGENESIS; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INTRON; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLICEOSOME;

3' UNTRANSLATED REGIONS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; ENDOSOMES; GENE EXPRESSION REGULATION; GENES, REPORTER; HISTONES; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INTRONS; MAMMALS; MOLECULAR SEQUENCE DATA; MORPHOLINOS; NEUTROPENIA; POINT MUTATION; POLYADENYLATION; RNA SPLICE SITES; RNA SPLICING; RNA STABILITY; RNA, MESSENGER; RNA, SMALL NUCLEAR; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY;

EID: 84867572205     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.252     Document Type: Article

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