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Volumn 27, Issue 11, 2012, Pages 2242-2250

Selective glucocorticoid receptor modulation maintains bone mineral density in mice

Author keywords

BONE REMODELING; COMPOUND A; DKK 1; GLUCOCORTICOID INDUCED OSTEOPOROSIS; RANKL

Indexed keywords

ALKALINE PHOSPHATASE; COMPOUND A; DICKKOPF 1 PROTEIN; GLUCOCORTICOID RECEPTOR; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PREDNISOLONE; PROCOLLAGEN C PROTEINASE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 84867559755     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1688     Document Type: Article
Times cited : (78)

References (28)
  • 1
  • 2
    • 70349774455 scopus 로고    scopus 로고
    • Minireview: Live and let die: Molecular effects of glucocorticoids on bone cells
    • Hofbauer LC, Rauner M., Minireview: live and let die: molecular effects of glucocorticoids on bone cells. Mol Endocrinol. 2009; 23: 1525-31.
    • (2009) Mol Endocrinol. , vol.23 , pp. 1525-1531
    • Hofbauer, L.C.1    Rauner, M.2
  • 3
    • 34548554688 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis: Pathophysiology and therapy
    • DOI 10.1007/s00198-007-0394-0
    • Canalis E, Mazziotti G, Giustina A, Bilezikian JP., Glucocorticoid- induced osteoporosis: pathophysiology and therapy. Osteoporos Int. 2007; 18: 1319-28. (Pubitemid 47389469)
    • (2007) Osteoporosis International , vol.18 , Issue.10 , pp. 1319-1328
    • Canalis, E.1    Mazziotti, G.2    Giustina, A.3    Bilezikian, J.P.4
  • 4
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, Spelsberg TC, Khosla S., Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology. 1999; 140: 4382-9. (Pubitemid 30666099)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Lacey, D.L.4    Dunstan, C.R.5    Spelsberg, T.C.6    Khosla, S.7
  • 5
    • 38149088611 scopus 로고    scopus 로고
    • Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels
    • Kondo T, Kitazawa R, Yamaguchi A, Kitazawa S., Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. J Cell Biochem. 2008; 103: 335-45.
    • (2008) J Cell Biochem. , vol.103 , pp. 335-345
    • Kondo, T.1    Kitazawa, R.2    Yamaguchi, A.3    Kitazawa, S.4
  • 7
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts end osteocytes by glucocorticoids potential mechanisms of their deleterious effects on bone
    • Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC., Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J Clin Invest. 1998; 102: 274-82. (Pubitemid 28335186)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.2 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Michael Parfitt, A.3    Manolagas, S.C.4
  • 9
    • 1942424854 scopus 로고    scopus 로고
    • Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: Novel mechanism of glucocorticoid-induced osteoporosis
    • DOI 10.1016/j.bbrc.2004.04.025, PII S0006291X04007338
    • Ohnaka K, Taniguchi H, Kawate H, Nawata H, Takayanagi R., Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis. Biochem Biophys Res Commun. 2004; 318: 259-64. (Pubitemid 38526274)
    • (2004) Biochemical and Biophysical Research Communications , vol.318 , Issue.1 , pp. 259-264
    • Ohnaka, K.1    Taniguchi, H.2    Kawate, H.3    Nawata, H.4    Takayanagi, R.5
  • 10
    • 41549138806 scopus 로고    scopus 로고
    • Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss
    • Wang FS, Ko JY, Yeh DW, Ke HC, Wu HL., Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss. Endocrinology. 2008; 149: 1793-801.
    • (2008) Endocrinology. , vol.149 , pp. 1793-1801
    • Wang, F.S.1    Ko, J.Y.2    Yeh, D.W.3    Ke, H.C.4    Wu, H.L.5
  • 12
    • 72449131349 scopus 로고    scopus 로고
    • Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells
    • Mak W, Shao X, Dunstan CR, Seibel MJ, Zhou H., Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells. Calcif Tissue Int. 2009; 85: 538-45.
    • (2009) Calcif Tissue Int. , vol.85 , pp. 538-545
    • Mak, W.1    Shao, X.2    Dunstan, C.R.3    Seibel, M.J.4    Zhou, H.5
  • 15
    • 75149156175 scopus 로고    scopus 로고
    • Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis
    • van Loo G, Sze M, Bougarne N, Praet J, Mc Guire C, Ullrich A, Haegeman G, Prinz M, Beyaert R, De Bosscher K., Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis. Mol Endocrinol. 2010; 24: 310-22.
    • (2010) Mol Endocrinol. , vol.24 , pp. 310-322
    • Van Loo, G.1    Sze, M.2    Bougarne, N.3    Praet, J.4    Mc Guire, C.5    Ullrich, A.6    Haegeman, G.7    Prinz, M.8    Beyaert, R.9    De Bosscher, K.10
  • 16
    • 78650850288 scopus 로고    scopus 로고
    • Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells
    • Rauner M, Goettsch C, Stein N, Thiele S, Bornhaeuser M, De Bosscher K, Haegeman G, Tuckermann J, Hofbauer LC., Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells. Endocrinology. 2011; 152: 103-12.
    • (2011) Endocrinology. , vol.152 , pp. 103-112
    • Rauner, M.1    Goettsch, C.2    Stein, N.3    Thiele, S.4    Bornhaeuser, M.5    De Bosscher, K.6    Haegeman, G.7    Tuckermann, J.8    Hofbauer, L.C.9
  • 18
    • 0031012174 scopus 로고    scopus 로고
    • Mechanism for the stabilization in vivo of the aziridine precursor 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride by serum proteins
    • DOI 10.1016/S0006-2952(96)00661-2, PII S0006295296006612
    • Louw A, Swart P, de Kock SS, van der Merwe KJ., Mechanism for the stabilization in vivo of the aziridine precursor - (4-acetoxyphenyl)-2-chloro-N- methyl-ethylammonium chloride by serum proteins. Biochem Pharmacol. 1997; 53: 189-97. (Pubitemid 27013474)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.2 , pp. 189-197
    • Louw, A.1    Swart, P.2    De Kock, S.S.3    Van Der Merwe, K.J.4
  • 20
    • 0346749741 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis
    • DOI 10.1159/000074506
    • Compston J., Glucocorticoid-induced osteoporosis. Horm Res. 2003; 60 (Suppl 3): 77-9. (Pubitemid 37548209)
    • (2003) Hormone Research , vol.60 , Issue.SUPPL. 3 , pp. 77-79
    • Compston, J.1
  • 21
    • 70349247894 scopus 로고    scopus 로고
    • Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
    • Zhang Z, Zhang ZY, Schluesener HJ., Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J Immunol. 2009; 183: 3081-91.
    • (2009) J Immunol. , vol.183 , pp. 3081-3091
    • Zhang, Z.1    Zhang, Z.Y.2    Schluesener, H.J.3
  • 23
    • 33846189394 scopus 로고    scopus 로고
    • The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438
    • DOI 10.1016/j.mce.2006.11.006, PII S0303720706005302
    • Owen HC, Miner JN, Ahmed SF, Farquharson C., The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438. Mol Cell Endocrinol. 2007; 264: 164-70. (Pubitemid 46097311)
    • (2007) Molecular and Cellular Endocrinology , vol.264 , Issue.1-2 , pp. 164-170
    • Owen, H.C.1    Miner, J.N.2    Ahmed, S.F.3    Farquharson, C.4
  • 24
    • 33751501004 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density
    • DOI 10.1210/en.2006-0459
    • Jia D, O'Brien CA, Stewart SA, Manolagas SC, Weinstein RS., Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinology. 2006; 147: 5592-9. (Pubitemid 44833476)
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5592-5599
    • Jia, D.1    O'Brien, C.A.2    Stewart, S.A.3    Manolagas, S.C.4    Weinstein, R.S.5
  • 25
    • 33646113165 scopus 로고    scopus 로고
    • Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells
    • Humphrey EL, Williams JH, Davie MW, Marshall MJ., Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells. Bone. 2006; 38: 652-61.
    • (2006) Bone. , vol.38 , pp. 652-661
    • Humphrey, E.L.1    Williams, J.H.2    Davie, M.W.3    Marshall, M.J.4
  • 28
    • 79251493453 scopus 로고    scopus 로고
    • The amazing osteocyte
    • Bonewald LF., The amazing osteocyte. J Bone Miner Res. 2011; 26: 229-38.
    • (2011) J Bone Miner Res. , vol.26 , pp. 229-238
    • Bonewald, L.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.