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Angewandte Chemie - International Edition

Volumn 51, Issue 42, 2012, Pages 10664-10669

Minimally invasive mutagenesis gives rise to a biosynthetic polyketide library

(6) Kushnir, Susanna a Sundermann, Uschi a Yahiaoui, Samir a Brockmeyer, Andreas b Janning, Petra b Schulz, Frank a

a TU DORTMUND UNIVERSITY (Germany)

b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY (Germany)

Author keywords

biosynthesis; enzymes; mutagenesis; natural products; polyketides

Indexed keywords

POLYKETIDE; POLYKETIDE SYNTHASE;

ARTICLE; CHEMISTRY; GENETICS; METABOLISM; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; SYNTHESIS;

MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENESIS; OXIDATION-REDUCTION; POLYKETIDE SYNTHASES; POLYKETIDES;

EID: 84867512666 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201202438 Document Type: Article

Times cited : (47)

References (37)

1
- 84862701661
- A. Kirschning, F. Hahn, Angew. Chem. 2012, 124, 4086
- (2012) Angew. Chem. , vol.124 , pp. 4086
- Kirschning, A.¹ Hahn, F.²

2
- 84859957277
- Angew. Chem. Int. Ed. 2012, 51, 4012.
- (2012) Angew. Chem. Int. Ed. , vol.51 , pp. 4012

3
- 76649101190
- C. Hertweck, Angew. Chem. 2009, 121, 4782
- (2009) Angew. Chem. , vol.121 , pp. 4782
- Hertweck, C.¹

4
- 69249202590
- Angew. Chem. Int. Ed. 2009, 48, 4688.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 4688

5
- 84859643086
- F. T. Wong, C. Khosla, Curr. Opin. Chem. Biol. 2012, 16, 117.
- (2012) Curr. Opin. Chem. Biol. , vol.16 , pp. 117
- Wong, F.T.¹ Khosla, C.²

6
- 79960767887
- D. H. Kwan, F. Schulz, Molecules 2011, 16, 6092.
- (2011) Molecules , vol.16 , pp. 6092
- Kwan, D.H.¹ Schulz, F.²

7
- 0014217184
- A. Agtarap, J. W. Chamberlin, M. Pinkerton, L. K. Steinrauf, J. Am. Chem. Soc. 1967, 89, 5737.
- (1967) J. Am. Chem. Soc. , vol.89 , pp. 5737
- Agtarap, A.¹ Chamberlin, J.W.² Pinkerton, M.³ Steinrauf, L.K.⁴

8
- 0020585628
- A. A. Ajaz, J. A. Robinson, Chem. Commun. 1983, 679.
- (1983) Chem. Commun. , pp. 679
- Ajaz, A.A.¹ Robinson, J.A.²

9
- 0141789847
- M. Oliynyk, C. B. W. Stark, A. Bhatt, M. A. Jones, Z. A. Hughes-Thomas, C. Wilkinson, Z. Oliynyk, Y. Demydchuk, J. Staunton, P. F. Leadlay, Mol. Microbiol. 2003, 49, 1179.
- (2003) Mol. Microbiol. , vol.49 , pp. 1179
- Oliynyk, M.¹ Stark, C.B.W.² Bhatt, A.³ Jones, M.A.⁴ Hughes-Thomas, Z.A.⁵ Wilkinson, C.⁶ Oliynyk, Z.⁷ Demydchuk, Y.⁸ Staunton, J.⁹ Leadlay, P.F.¹⁰

10
- 0035675996
- P. F. Leadlay, J. Staunton, M. Oliynyk, C. Bisang, J. Cortes, E. Frost, Z. A. Hughes-Thomas, M. A. Jones, S. G. Kendrew, J. B. Lester, P. F. Long, H. A. I. McArthur, E. L. McCormick, Z. Oliynyk, C. B. W. Stark, C. J. Wilkinson, J. Ind. Microbiol. Biotechnol. 2001, 27, 360.
- (2001) J. Ind. Microbiol. Biotechnol. , vol.27 , pp. 360
- Leadlay, P.F.¹ Staunton, J.² Oliynyk, M.³ Bisang, C.⁴ Cortes, J.⁵ Frost, E.⁶ Hughes-Thomas, Z.A.⁷ Jones, M.A.⁸ Kendrew, S.G.⁹ Lester, J.B.¹⁰ Long, P.F.¹¹ McArthur, H.A.I.¹² McCormick, E.L.¹³ Oliynyk, Z.¹⁴ Stark, C.B.W.¹⁵ Wilkinson, C.J.¹⁶

11
- 1542292778
- Z. A. Hughes-Thomas, C. B. W. Stark, I. U. Bohm, J. Staunton, P. F. Leadlay, Angew. Chem. 2003, 115, 4613
- (2003) Angew. Chem. , vol.115 , pp. 4613
- Hughes-Thomas, Z.A.¹ Stark, C.B.W.² Bohm, I.U.³ Staunton, J.⁴ Leadlay, P.F.⁵

12
- 0141447396
- Angew. Chem. Int. Ed. 2003, 42, 4475.
- (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 4475

13
- 30544434619
- K. J. Weissman, P. F. Leadlay, Nat. Rev. Microbiol. 2005, 3, 925.
- (2005) Nat. Rev. Microbiol. , vol.3 , pp. 925
- Weissman, K.J.¹ Leadlay, P.F.²

14
- 79251519303
- U. Sundermann, S. Kushnir, F. Schulz, Nachr. Chem. 2011, 59, 29.
- (2011) Nachr. Chem. , vol.59 , pp. 29
- Sundermann, U.¹ Kushnir, S.² Schulz, F.³

15
- 42449158575
- C. P. Ridley, H. Y. Lee, C. Khosla, Proc. Natl. Acad. Sci. USA 2008, 105, 4595.
- (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4595
- Ridley, C.P.¹ Lee, H.Y.² Khosla, C.³

16
- 79959424209
- L. B. Pickens, Y. Tang, Y.-H. Chooi, Ann. Rev. Chem. Biomol. Eng. 2011, 2, 211.
- (2011) Ann. Rev. Chem. Biomol. Eng. , vol.2 , pp. 211
- Pickens, L.B.¹ Tang, Y.² Chooi, Y.-H.³

17
- 0037435603
- R. Reid, M. Piagentini, E. Rodriguez, G. Ashley, N. Viswanathan, J. Carney, D. V. Santi, C. R. Hutchinson, R. McDaniel, Biochemistry 2003, 42, 72.
- (2003) Biochemistry , vol.42 , pp. 72
- Reid, R.¹ Piagentini, M.² Rodriguez, E.³ Ashley, G.⁴ Viswanathan, N.⁵ Carney, J.⁶ Santi, D.V.⁷ Hutchinson, C.R.⁸ McDaniel, R.⁹

18
- 0026559262
- S. Donadio, L. Katz, Gene 1992, 111, 51.
- (1992) Gene , vol.111 , pp. 51
- Donadio, S.¹ Katz, L.²

19
- 29044437969
- J. Q. Wu, T. J. Zaleski, C. Valenzano, C. Khosla, D. E. Cane, J. Am. Chem. Soc. 2005, 127, 17393.
- (2005) J. Am. Chem. Soc. , vol.127 , pp. 17393
- Wu, J.Q.¹ Zaleski, T.J.² Valenzano, C.³ Khosla, C.⁴ Cane, D.E.⁵

20
- 33644764239
- S. E. F. Borgos, H. Sletta, E. Fjaervik, T. Brautaset, T. E. Ellingsen, O. M. Gulliksen, S. B. Zotchev, Arch. Microbiol. 2006, 185, 165.
- (2006) Arch. Microbiol. , vol.185 , pp. 165
- Borgos, S.E.F.¹ Sletta, H.² Fjaervik, E.³ Brautaset, T.⁴ Ellingsen, T.E.⁵ Gulliksen, O.M.⁶ Zotchev, S.B.⁷

21
- 33746272142
- A. Bhatt, C. B. W. Stark, B. M. Harvey, A. R. Gallimore, Y. A. Demydchuk, J. B. Spencer, J. Staunton, P. F. Leadlay, Angew. Chem. 2005, 117, 7237
- (2005) Angew. Chem. , vol.117 , pp. 7237
- Bhatt, A.¹ Stark, C.B.W.² Harvey, B.M.³ Gallimore, A.R.⁴ Demydchuk, Y.A.⁵ Spencer, J.B.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

22
- 27744442699
- Angew. Chem. Int. Ed. 2005, 44, 7075.
- (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 7075

23
- 84867545195
- in revision
- S. Kushnir, U. Sundermann, F. Schulz, Asian J. Biotechnol. 2012, in revision.
- (2012) Asian J. Biotechnol.
- Kushnir, S.¹ Sundermann, U.² Schulz, F.³

24
- 0003869903
- John Innes Foundation
- T. Kieser, M.J. Bibb, M.J. Buttner, K.F. Chater, D.A. Hopwood, Practical Streptomyces Genetics, John Innes Foundation, 2000.
- (2000) Practical Streptomyces Genetics
- Kieser, T.¹ Bibb, M.J.² Buttner, M.J.³ Chater, K.F.⁴ Hopwood, D.A.⁵

25
- 0024341196
- G. Muth, B. Nussbaumer, W. Wohlleben, A. Puhler, Mol. Gen. Genet. 1989, 219, 341.
- (1989) Mol. Gen. Genet. , vol.219 , pp. 341
- Muth, G.¹ Nussbaumer, B.² Wohlleben, W.³ Puhler, A.⁴

26
- 77954675603
- J. Piel, Nat. Prod. Rep. 2010, 27, 996.
- (2010) Nat. Prod. Rep. , vol.27 , pp. 996
- Piel, J.¹

27
- 67650281479
- K. M. Fisch, C. Gurgui, N. Heycke, S. A. vanderSar, S. A. Anderson, V. L. Webb, S. Taudien, M. Platzer, B. K. Rubio, S. J. Robinson, P. Crews, J. Piel, Nat. Chem. Biol. 2009, 5, 494.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 494
- Fisch, K.M.¹ Gurgui, C.² Heycke, N.³ Vandersar, S.A.⁴ Anderson, S.A.⁵ Webb, V.L.⁶ Taudien, S.⁷ Platzer, M.⁸ Rubio, B.K.⁹ Robinson, S.J.¹⁰ Crews, P.¹¹ Piel, J.¹²

28
- 57649200475
- M. Avi, R. M. Wiedner, H. Griengl, H. Schwab, Chem. Eur. J. 2008, 14, 11415.
- (2008) Chem. Eur. J. , vol.14 , pp. 11415
- Avi, M.¹ Wiedner, R.M.² Griengl, H.³ Schwab, H.⁴

29
- 84858954441
- K. Jensen, H. Niederkrüger, K. Zimmermann, A. L. Vagstad, J. Moldenhauer, N. Brendel, S. Frank, P. Pöplau, C. Kohlhaas, C. A. Townsend, M. Oldiges, C. Hertweck, J. Piel, Chem. Biol. 2012, 19, 329.
- (2012) Chem. Biol. , vol.19 , pp. 329
- Jensen, K.¹ Niederkrüger, H.² Zimmermann, K.³ Vagstad, A.L.⁴ Moldenhauer, J.⁵ Brendel, N.⁶ Frank, S.⁷ Pöplau, P.⁸ Kohlhaas, C.⁹ Townsend, C.A.¹⁰ Oldiges, M.¹¹ Hertweck, C.¹² Piel, J.¹³

30
- 84858983871
- J. C. Kwan, E. W. Schmidt, Chem. Biol. 2012, 19, 309.
- (2012) Chem. Biol. , vol.19 , pp. 309
- Kwan, J.C.¹ Schmidt, E.W.²

31
- 0037073685
- B. S. Kim, T. A. Cropp, B. J. Beck, D. H. Sherman, K. A. Reynolds, J. Biol. Chem. 2002, 277, 48028.
- (2002) J. Biol. Chem. , vol.277 , pp. 48028
- Kim, B.S.¹ Cropp, T.A.² Beck, B.J.³ Sherman, D.H.⁴ Reynolds, K.A.⁵

32
- 0033529935
- T.-W. Yu, Y. Shen, Y. Doi-Katayama, L. Tang, C. Park, B. S. Moore, C. R. Hutchinson, H. G. Floss, Proc. Natl. Acad. Sci. USA 1999, 96, 9051.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9051
- Yu, T.-W.¹ Shen, Y.² Doi-Katayama, Y.³ Tang, L.⁴ Park, C.⁵ Moore, B.S.⁶ Hutchinson, C.R.⁷ Floss, H.G.⁸

33
- 27144509740
- H. G. Menzella, R. Reid, J. R. Carney, S. S. Chandran, S. J. Reisinger, K. G. Patel, D. A. Hopwood, D. V. Santi, Nat. Biotechnol. 2005, 23, 1171.
- (2005) Nat. Biotechnol. , vol.23 , pp. 1171
- Menzella, H.G.¹ Reid, R.² Carney, J.R.³ Chandran, S.S.⁴ Reisinger, S.J.⁵ Patel, K.G.⁶ Hopwood, D.A.⁷ Santi, D.V.⁸

34
- 33847076126
- H. G. Menzella, J. R. Carney, D. V. Santi, Chem. Biol. 2007, 14, 143.
- (2007) Chem. Biol. , vol.14 , pp. 143
- Menzella, H.G.¹ Carney, J.R.² Santi, D.V.³

35
- 0033515090
- R. McDaniel, A. Thamchaipenet, C. Gustafsson, H. Fu, M. Betlach, M. Betlach, G. Ashley, Proc. Natl. Acad. Sci. USA 1999, 96, 1846.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1846
- McDaniel, R.¹ Thamchaipenet, A.² Gustafsson, C.³ Fu, H.⁴ Betlach, M.⁵ Betlach, M.⁶ Ashley, G.⁷

36
- 0001452901
- R. Breinbauer, I. R. Vetter, H. Waldmann, Angew. Chem. 2002, 114, 3002
- (2002) Angew. Chem. , vol.114 , pp. 3002
- Breinbauer, R.¹ Vetter, I.R.² Waldmann, H.³

37
- 0037119336
- Angew. Chem. Int. Ed. 2002, 41, 2878.
- (2002) Angew. Chem. Int. Ed. , vol.41 , pp. 2878

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