-
1
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network Collaborators
-
Cancer Genome Atlas Research Network Collaborators (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
2
-
-
7144261725
-
The class III variant of the epidermal growth factor receptor (EGFRvIII): Characterization and utilization as an immunotherapeutic target
-
Wikstrand CJ, Reist CJ, Archer GE, Zalutsky MR, and Bigner DD (1998). The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target. J Neurovirol 4, 148-158.
-
(1998)
J Neurovirol
, vol.4
, pp. 148-158
-
-
Wikstrand, C.J.1
Reist, C.J.2
Archer, G.E.3
Zalutsky, M.R.4
Bigner, D.D.5
-
3
-
-
27644543354
-
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
-
Abounader R and Laterra J (2005). Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Neuro Oncol 7, 436-451.
-
(2005)
Neuro Oncol
, vol.7
, pp. 436-451
-
-
Abounader, R.1
Laterra, J.2
-
4
-
-
34848855124
-
The MET receptor tyrosine kinase in invasion and metastasis
-
Benvenuti S and Comoglio PM (2007). The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol 213, 316-325.
-
(2007)
J Cell Physiol
, vol.213
, pp. 316-325
-
-
Benvenuti, S.1
Comoglio, P.M.2
-
5
-
-
81155154258
-
EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction
-
Jin X, Yin J, Kim SH, Sohn YW, Beck S, Lim YC, Nam DH, Choi YJ, and Kim H (2011). EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction. Cancer Res 71, 7125-7134.
-
(2011)
Cancer Res
, vol.71
, pp. 7125-7134
-
-
Jin, X.1
Yin, J.2
Kim, S.H.3
Sohn, Y.W.4
Beck, S.5
Lim, Y.C.6
Nam, D.H.7
Choi, Y.J.8
Kim, H.9
-
6
-
-
79955865397
-
Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity
-
Wang H, Zhou M, Shi B, Zhang Q, Jiang H, Sun Y, Liu J, Zhou K, Yao M, Gu J, et al. (2011). Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity. Neoplasia 13, 461-471.
-
(2011)
Neoplasia
, vol.13
, pp. 461-471
-
-
Wang, H.1
Zhou, M.2
Shi, B.3
Zhang, Q.4
Jiang, H.5
Sun, Y.6
Liu, J.7
Zhou, K.8
Yao, M.9
Gu, J.10
-
8
-
-
0032549537
-
The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor β receptor
-
Habib AA, Hognason T, Ren J, Stefansson K, and Ratan RR (1998). The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor β receptor. J Biol Chem 273, 6885-6891.
-
(1998)
J Biol Chem
, vol.273
, pp. 6885-6891
-
-
Habib, A.A.1
Hognason, T.2
Ren, J.3
Stefansson, K.4
Ratan, R.R.5
-
9
-
-
0036551486
-
Scatter-factor and semaphorin receptors: Cell signalling for invasive growth
-
Trusolino L and Comoglio PM (2002). Scatter-factor and semaphorin receptors: cell signalling for invasive growth. Nat Rev Cancer 2, 289-300.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 289-300
-
-
Trusolino, L.1
Comoglio, P.M.2
-
10
-
-
33845688497
-
ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas
-
Yasmeen A, Bismar TA, and Al Moustafa AE (2006). ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas. Future Oncol 2, 765-781.
-
(2006)
Future Oncol
, vol.2
, pp. 765-781
-
-
Yasmeen, A.1
Bismar, T.A.2
Al Moustafa, A.E.3
-
11
-
-
0030656205
-
Expression of c-Met correlates with grade of malignancy in human astrocytic tumours: An immunohistochemical study
-
Nabeshima K, Shimao Y, Sato S, Kataoka H, Moriyama T, Kawano H, Wakisaka S, and Koono M (1997). Expression of c-Met correlates with grade of malignancy in human astrocytic tumours: an immunohistochemical study. Histopathology 31, 436-443.
-
(1997)
Histopathology
, vol.31
, pp. 436-443
-
-
Nabeshima, K.1
Shimao, Y.2
Sato, S.3
Kataoka, H.4
Moriyama, T.5
Kawano, H.6
Wakisaka, S.7
Koono, M.8
-
12
-
-
82355191770
-
EGFR and KRAS mutations and altered c-Met gene copy numbers in primary nonsmall cell lung cancer and associated stage N2 lymph node-metastasis
-
Han CB, Ma JT, Li F, Zhao JZ, Jing W, Zhou Y, and Zou HW (2012). EGFR and KRAS mutations and altered c-Met gene copy numbers in primary nonsmall cell lung cancer and associated stage N2 lymph node-metastasis. Cancer Lett 314, 63-72.
-
(2012)
Cancer Lett
, vol.314
, pp. 63-72
-
-
Han, C.B.1
Ma, J.T.2
Li, F.3
Zhao, J.Z.4
Jing, W.5
Zhou, Y.6
Zou, H.W.7
-
13
-
-
78549278133
-
Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells
-
Hochgrafe F, Zhang L, O'Toole SA, Browne BC, Pinese M, Porta CA, Lehrbach GM, Croucher DR, Rickwood D, Boulghourjian A, et al. (2010). Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells. Cancer Res 70, 9391-9401.
-
(2010)
Cancer Res
, vol.70
, pp. 9391-9401
-
-
Hochgrafe, F.1
Zhang, L.2
O'Toole, S.A.3
Browne, B.C.4
Pinese, M.5
Porta, C.A.6
Lehrbach, G.M.7
Croucher, D.R.8
Rickwood, D.9
Boulghourjian, A.10
-
14
-
-
77952979261
-
EGFR-targeted therapy in malignant glioma: Novel aspects and mechanisms of drug resistance
-
Lo HW (2010). EGFR-targeted therapy in malignant glioma: novel aspects and mechanisms of drug resistance. Curr Mol Pharmacol 3, 37-52.
-
(2010)
Curr Mol Pharmacol
, vol.3
, pp. 37-52
-
-
Lo, H.W.1
-
15
-
-
33947207989
-
Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival
-
Lutterbach B, Zeng Q, Davis LJ, Hatch H, Hang G, Kohl NE, Gibbs JB, and Pan BS (2007). Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. Cancer Res 67, 2081-2088.
-
(2007)
Cancer Res
, vol.67
, pp. 2081-2088
-
-
Lutterbach, B.1
Zeng, Q.2
Davis, L.J.3
Hatch, H.4
Hang, G.5
Kohl, N.E.6
Gibbs, J.B.7
Pan, B.S.8
-
16
-
-
79951831653
-
GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway
-
Pathi SS, Jutooru I, Chadalapaka G, Sreevalsan S, Anand S, Thatcher GR, and Safe S (2011). GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway. Mol Cancer Res 9, 195-202.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 195-202
-
-
Pathi, S.S.1
Jutooru, I.2
Chadalapaka, G.3
Sreevalsan, S.4
Anand, S.5
Thatcher, G.R.6
Safe, S.7
-
17
-
-
79960300164
-
Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells
-
Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, and Siegfried JM (2011). Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells. Clin Cancer Res 17, 4425-4438.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4425-4438
-
-
Xu, H.1
Stabile, L.P.2
Gubish, C.T.3
Gooding, W.E.4
Grandis, J.R.5
Siegfried, J.M.6
-
18
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, et al. (2007). MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316, 1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
Lindeman, N.7
Gale, C.M.8
Zhao, X.9
Christensen, J.10
-
19
-
-
78649420006
-
MET signalling: Principles and functions in development, organ regeneration and cancer
-
Trusolino L, Bertotti A, and Comoglio PM (2010). MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol 11, 834-848.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 834-848
-
-
Trusolino, L.1
Bertotti, A.2
Comoglio, P.M.3
-
20
-
-
77954405035
-
EGFR/ Met association regulates EGFR TKI resistance in breast cancer
-
Mueller KL, Yang ZQ, Haddad R, Ethier SP, and Boerner JL (2010). EGFR/ Met association regulates EGFR TKI resistance in breast cancer. J Mol Signal 5, 8.
-
(2010)
J Mol Signal
, vol.5
, pp. 8
-
-
Mueller, K.L.1
Yang, Z.Q.2
Haddad, R.3
Ethier, S.P.4
Boerner, J.L.5
-
21
-
-
38649119730
-
Signaling networks assembled by oncogenic EGFR and c-Met
-
Guo A, Villen J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, et al. (2008). Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci USA 105, 692-697.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 692-697
-
-
Guo, A.1
Villen, J.2
Kornhauser, J.3
Lee, K.A.4
Stokes, M.P.5
Rikova, K.6
Possemato, A.7
Nardone, J.8
Innocenti, G.9
Wetzel, R.10
-
22
-
-
73949083511
-
Oncogenic EGFR signaling networks in glioma
-
Huang PH, Xu AM, and White FM (2009). Oncogenic EGFR signaling networks in glioma. Sci Signal 2, re6.
-
(2009)
Sci Signal
, vol.2
-
-
Huang, P.H.1
Xu, A.M.2
White, F.M.3
-
23
-
-
34547881522
-
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma
-
Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, and White FM (2007). Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci USA 104, 12867-12872.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12867-12872
-
-
Huang, P.H.1
Mukasa, A.2
Bonavia, R.3
Flynn, R.A.4
Brewer, Z.E.5
Cavenee, W.K.6
Furnari, F.B.7
White, F.M.8
-
24
-
-
67649365635
-
Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors
-
Karamouzis MV, Konstantinopoulos PA, and Papavassiliou AG (2009). Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors. Lancet Oncol 10, 709-717.
-
(2009)
Lancet Oncol
, vol.10
, pp. 709-717
-
-
Karamouzis, M.V.1
Konstantinopoulos, P.A.2
Papavassiliou, A.G.3
-
25
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
Kris MG, Natale RB, Herbst RS, Lynch TJ Jr, Prager D, Belani CP, Schiller JH, Kelly K, Spiridonidis H, Sandler A, et al. (2003). Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 290, 2149-2158.
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch Jr., T.J.4
Prager, D.5
Belani, C.P.6
Schiller, J.H.7
Kelly, K.8
Spiridonidis, H.9
Sandler, A.10
-
26
-
-
0030690583
-
Met and hepatocyte growth factor/ scatter factor expression in human gliomas
-
Koochekpour S, Jeffers M, Rulong S, Taylor G, Klineberg E, Hudson EA, Resau JH, and Vande Woude GF (1997). Met and hepatocyte growth factor/ scatter factor expression in human gliomas. Cancer Res 57, 5391-5398.
-
(1997)
Cancer Res
, vol.57
, pp. 5391-5398
-
-
Koochekpour, S.1
Jeffers, M.2
Rulong, S.3
Taylor, G.4
Klineberg, E.5
Hudson, E.A.6
Resau, J.H.7
Vande Woude, G.F.8
-
27
-
-
79953059991
-
Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1
-
Velpula KK, Dasari VR, Tsung AJ, Gondi CS, Klopfenstein JD, Mohanam S, and Rao JS (2011). Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1. PLoS One 6, e18017.
-
(2011)
PLoS One
, vol.6
-
-
Velpula, K.K.1
Dasari, V.R.2
Tsung, A.J.3
Gondi, C.S.4
Klopfenstein, J.D.5
Mohanam, S.6
Rao, J.S.7
-
28
-
-
80755159105
-
Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT
-
Asuthkar S, Nalla AK, Gondi CS, Dinh DH, Gujrati M, Mohanam S, and Rao JS (2011). Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT. Neuro Oncol 13, 1059-1073.
-
(2011)
Neuro Oncol
, vol.13
, pp. 1059-1073
-
-
Asuthkar, S.1
Nalla, A.K.2
Gondi, C.S.3
Dinh, D.H.4
Gujrati, M.5
Mohanam, S.6
Rao, J.S.7
-
29
-
-
84862842906
-
Transcriptional repression of MAD-MAX complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma
-
Velpula KK, Dasari VR, Tsung AJ, Dinh DH, and Rao JS (2011). Transcriptional repression of MAD-MAX complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma. Stem Cells Dev 21, 1779-1793.
-
(2011)
Stem Cells Dev
, vol.21
, pp. 1779-1793
-
-
Velpula, K.K.1
Dasari, V.R.2
Tsung, A.J.3
Dinh, D.H.4
Rao, J.S.5
-
30
-
-
51649130231
-
Receptor trafficking controls weak signal delivery: A strategy used by c-Met for STAT3 nuclear accumulation
-
Kermorgant S and Parker PJ (2008). Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J Cell Biol 182, 855-863.
-
(2008)
J Cell Biol
, vol.182
, pp. 855-863
-
-
Kermorgant, S.1
Parker, P.J.2
-
31
-
-
80053150736
-
Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways
-
Wang Y, Chen L, Bao Z, Li S, You G, Yan W, Shi Z, Liu Y, Yang P, Zhang W, et al. (2011). Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways. Oncol Rep 26, 1173-1180.
-
(2011)
Oncol Rep
, vol.26
, pp. 1173-1180
-
-
Wang, Y.1
Chen, L.2
Bao, Z.3
Li, S.4
You, G.5
Yan, W.6
Shi, Z.7
Liu, Y.8
Yang, P.9
Zhang, W.10
-
32
-
-
80052023181
-
Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: Pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies
-
Mimeault M and Batra SK (2011). Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies. Brain Pathol 21, 479-500.
-
(2011)
Brain Pathol
, vol.21
, pp. 479-500
-
-
Mimeault, M.1
Batra, S.K.2
-
33
-
-
77955590310
-
Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway
-
Dasari VR, Kaur K, Velpula KK, Gujrati M, Fassett D, Klopfenstein JD, Dinh DH, and Rao JS (2010). Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway. PLoS One 5, e10350.
-
(2010)
PLoS One
, vol.5
-
-
Dasari, V.R.1
Kaur, K.2
Velpula, K.K.3
Gujrati, M.4
Fassett, D.5
Klopfenstein, J.D.6
Dinh, D.H.7
Rao, J.S.8
-
34
-
-
33749344520
-
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
-
Lee TK, Poon RT, Yuen AP, Ling MT, Kwok WK, Wang XH, Wong YC, Guan XY, Man K, Chau KL, et al. (2006). Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res 12, 5369-5376.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5369-5376
-
-
Lee, T.K.1
Poon, R.T.2
Yuen, A.P.3
Ling, M.T.4
Kwok, W.K.5
Wang, X.H.6
Wong, Y.C.7
Guan, X.Y.8
Man, K.9
Chau, K.L.10
-
35
-
-
0033882022
-
Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase-and AKTdependent pathways
-
Bowers DC, Fan S, Walter KA, Abounader R, Williams JA, Rosen EM, and Laterra J (2000). Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase-and AKTdependent pathways. Cancer Res 60, 4277-4283.
-
(2000)
Cancer Res
, vol.60
, pp. 4277-4283
-
-
Bowers, D.C.1
Fan, S.2
Walter, K.A.3
Abounader, R.4
Williams, J.A.5
Rosen, E.M.6
Laterra, J.7
-
36
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, Holmes AB, Gaffney PR, Reese CB, McCormick F, Tempst P, et al. (1998). Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279, 710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
-
37
-
-
27744535984
-
PI3KAKT pathway negatively controls EGFR-dependent DNA-binding activity of Stat3 in glioblastoma multiforme cells
-
Ghosh MK, Sharma P, Harbor PC, Rahaman SO, and Haque SJ (2005). PI3KAKT pathway negatively controls EGFR-dependent DNA-binding activity of Stat3 in glioblastoma multiforme cells. Oncogene 24, 7290-7300.
-
(2005)
Oncogene
, vol.24
, pp. 7290-7300
-
-
Ghosh, M.K.1
Sharma, P.2
Harbor, P.C.3
Rahaman, S.O.4
Haque, S.J.5
-
38
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I and Sawyers CL (2002). The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2, 489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
39
-
-
9144232309
-
Molecular mechanisms of glioma cell migration and invasion
-
Demuth T and Berens ME (2004). Molecular mechanisms of glioma cell migration and invasion. J Neurooncol 70, 217-228.
-
(2004)
J Neurooncol
, vol.70
, pp. 217-228
-
-
Demuth, T.1
Berens, M.E.2
-
40
-
-
36048994736
-
Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment
-
Hoelzinger DB, Demuth T, and Berens ME (2007). Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J Natl Cancer Inst 99, 1583-1593.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1583-1593
-
-
Hoelzinger, D.B.1
Demuth, T.2
Berens, M.E.3
-
41
-
-
33646404053
-
Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma
-
Taulli R, Scuoppo C, Bersani F, Accornero P, Forni PE, Miretti S, Grinza A, Allegra P, Schmitt-Ney M, Crepaldi T, et al. (2006). Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma. Cancer Res 66, 4742-4749.
-
(2006)
Cancer Res
, vol.66
, pp. 4742-4749
-
-
Taulli, R.1
Scuoppo, C.2
Bersani, F.3
Accornero, P.4
Forni, P.E.5
Miretti, S.6
Grinza, A.7
Allegra, P.8
Schmitt-Ney, M.9
Crepaldi, T.10
-
42
-
-
4644238311
-
EGFR mutations and sensitivity to gefitinib
-
Rich JN, Rasheed BK, and Yan H (2004). EGFR mutations and sensitivity to gefitinib. N Engl J Med 351, 1260-1261.
-
(2004)
N Engl J Med
, vol.351
, pp. 1260-1261
-
-
Rich, J.N.1
Rasheed, B.K.2
Yan, H.3
-
43
-
-
68949110285
-
Analysis of EGFR gene amplification, protein over-expression and tyrosine kinase domain mutation in recurrent glioblastoma
-
Toth J, Egervari K, Klekner A, Bognar L, Szanto J, Nemes Z, and Szollosi Z (2009). Analysis of EGFR gene amplification, protein over-expression and tyrosine kinase domain mutation in recurrent glioblastoma. Pathol Oncol Res 15, 225-229.
-
(2009)
Pathol Oncol Res
, vol.15
, pp. 225-229
-
-
Toth, J.1
Egervari, K.2
Klekner, A.3
Bognar, L.4
Szanto, J.5
Nemes, Z.6
Szollosi, Z.7
-
44
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies
-
Wheeler DL, Dunn EF, and Harari PM (2010). Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nat Rev Clin Oncol 7, 493-507.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
45
-
-
84862777227
-
c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma and independently contribute to migration and metastatic potential
-
Wu X, Zhou J, Rogers AM, Janne PA, Benedettini E, Loda M, and Hodi FS (2012). c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma and independently contribute to migration and metastatic potential. Melanoma Res 22, 123-132.
-
(2012)
Melanoma Res
, vol.22
, pp. 123-132
-
-
Wu, X.1
Zhou, J.2
Rogers, A.M.3
Janne, P.A.4
Benedettini, E.5
Loda, M.6
Hodi, F.S.7
-
46
-
-
83555172248
-
EGFR is dispensable for c-Met-mediated proliferation and survival activities in mouse adult liver oval cells
-
Martinez-Palacian A, del Castillo CG, Herrera B, Fernandez M, Roncero C, Fabregat I, and Sanchez A (2012). EGFR is dispensable for c-Met-mediated proliferation and survival activities in mouse adult liver oval cells. Cell Signal 24, 505-513.
-
(2012)
Cell Signal
, vol.24
, pp. 505-513
-
-
Martinez-Palacian, A.1
del Castillo, C.G.2
Herrera, B.3
Fernandez, M.4
Roncero, C.5
Fabregat, I.6
Sanchez, A.7
-
47
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
-
Sequist LV, von Pawel PJ, Garmey EG, Akerley WL, Brugger W, Ferrari D, Chen Y, Costa DB, Gerber DE, Orlov S, et al. (2011). Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol 29, 3307-3315.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3307-3315
-
-
Sequist, L.V.1
von Pawel, P.J.2
Garmey, E.G.3
Akerley, W.L.4
Brugger, W.5
Ferrari, D.6
Chen, Y.7
Costa, D.B.8
Gerber, D.E.9
Orlov, S.10
-
48
-
-
79960300164
-
Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells
-
Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, and Siegfried JM (2011). Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells. Clin Cancer Res 17, 4425-4438.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4425-4438
-
-
Xu, H.1
Stabile, L.P.2
Gubish, C.T.3
Gooding, W.E.4
Grandis, J.R.5
Siegfried, J.M.6
-
49
-
-
80051800007
-
HGFindependent potentiation of EGFR action by c-Met
-
Dulak AM, Gubish CT, Stabile LP, Henry C, and Siegfried JM (2011). HGFindependent potentiation of EGFR action by c-Met. Oncogene 30, 3625-3635.
-
(2011)
Oncogene
, vol.30
, pp. 3625-3635
-
-
Dulak, A.M.1
Gubish, C.T.2
Stabile, L.P.3
Henry, C.4
Siegfried, J.M.5
-
50
-
-
84856891114
-
Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma
-
Dasari VR, Velpula KK, Alapati K, Gujrati M, and Tsung AJ (2012). Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma. PLoS One 7, e31884.
-
(2012)
PLoS One
, vol.7
-
-
Dasari, V.R.1
Velpula, K.K.2
Alapati, K.3
Gujrati, M.4
Tsung, A.J.5
-
51
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, et al. (2007). Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 318, 287-290.
-
(2007)
Science
, vol.318
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
Nabioullin, R.4
Ponugoti, A.H.5
Wiedemeyer, R.6
Stegh, A.H.7
Bradner, J.E.8
Ligon, K.L.9
Brennan, C.10
|