Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT

Neuro-Oncology

Volumn 13, Issue 10, 2011, Pages 1059-1073

  Asuthkar, Swapna ^a   Nalla, Arun Kumar ^a   Gondi, Christopher S ^a   Dinh, Dzung H ^a   Gujrati, Meena ^a   Mohanam, Sanjeeva ^a   Rao, Jasti S ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

catenin; Epithelial mesenchymal transition (EMT); Ionizing radiation (IR); Matrix metallopeptidase 9 (MMP 9); Overexpression of Gadd45a (Ov exp Gadd45a)

Indexed keywords

BETA CATENIN; CYCLIN DEPENDENT KINASE 1; GELATINASE B; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45A; PROTEIN P53; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IONIZING RADIATION; MEDULLOBLASTOMA; MEDULLOBLASTOMA CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; CEREBELLAR NEOPLASMS; EPITHELIAL-MESENCHYMAL TRANSITION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; MATRIX METALLOPROTEINASE 9; MEDULLOBLASTOMA; MICE; MICE, NUDE; NUCLEAR PROTEINS; RADIATION TOLERANCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80755159105     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor109     Document Type: Article

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