Compromised Mitochondrial Fatty Acid Synthesis in Transgenic Mice Results in Defective Protein Lipoylation and Energy Disequilibrium

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Smith, Stuart ^a   Witkowski, Andrzej ^a   Moghul, Ayesha ^a   Yoshinaga, Yuko ^a   Nefedov, Michael ^a   de Jong, Pieter ^a   Feng, Dejiang ^a   Fong, Loren ^b   Tu, Yiping ^b   Hu, Yan ^b   Young, Stephen G ^b   Pham, Thomas ^a   Cheung, Carling ^a   Katzman, Shana M ^c   Brand, Martin D ^c   Quinlan, Casey L ^c   Fens, Marcel ^a   Kuypers, Frans ^a   Misquitta, Stephanie ^a   Griffey, Stephen M ^d   Tran, Son ^a   Gharib, Afshin ^a,e   Knudsen, Jens ^f   Hannibal Bach, Hans Kristian ^f   Wang, Grace ^a   Larkin, Sandra ^a   Thweatt, Jennifer ^a   Pasta, Saloni ^a   more..

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e DOMINICAN UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CYTOCHROME; FATTY ACID; GLYCOGEN; LACTIC ACID; MALONYL COENZYME A ACYL CARRIER PROTEIN TRANSACYLASE; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ALOPECIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CELL COUNT; CELL ISOLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY BALANCE; ENERGY DISEQUILIBRIUM; ENERGY METABOLISM; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; FECES ANALYSIS; FOOD INTAKE; GENE; GENOTYPE; GRIP STRENGTH; HYPOTHERMIA; KYPHOSIS; LIFESPAN; LIPOYLATION; MCAT GENE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MUSCLE STRENGTH; NONHUMAN; OPEN FIELD TEST; PHENOTYPE; PROTEIN EXPRESSION; ROTAROD TEST; TRANSGENIC MOUSE; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; ADIPOSE TISSUE, WHITE; ANEMIA; ANIMALS; CELL RESPIRATION; FATTY ACIDS; FEMALE; GENE KNOCKOUT TECHNIQUES; KETONE BODIES; LACTIC ACID; LIPOYLATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MYOCARDIUM; RECTAL PROLAPSE; SIGNAL TRANSDUCTION;

EID: 84867497045     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047196     Document Type: Article

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