Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 37, 2005, Pages 13188-13193

  Friedel, Roland H ^a   Plump, Andrew ^a,c   Lu, Xiaowei ^a   Spilker, Kerri ^a   Jolicoeur, Christine ^a   Wong, Karen ^a   Venkatesh, Tadmiri R ^b   Yaron, Avraham ^a   Hynes, Mary ^a   Chen, Bin ^a   Okada, Ami ^a   McConnell, Susan K ^a   Rayburn, Helen ^a   Tessier Lavigne, Marc ^a,d  

^a STANFORD UNIVERSITY   (United States)

^b CITY COLLEGE OF NEW YORK   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d GENENTECH INC   (United States)

Author keywords

ES cells; Gene trapping

Indexed keywords

SECRETORY PROTEIN; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ARTICLE; GENE EXPRESSION; GENE FUNCTION; GENE INSERTION; GENE TARGETING; GENE VECTOR; GENETIC ANALYSIS; GENOME; HOMOLOGOUS RECOMBINATION; MAMMALIAN GENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTERLESS GENE TRAP VECTOR;

ANIMALS; EMBRYO; GENE EXPRESSION PROFILING; GENE TARGETING; GENETIC VECTORS; GENOMICS; METHODS; MICE; MUTAGENESIS, INSERTIONAL; RECOMBINATION, GENETIC; STEM CELLS;

MAMMALIA;

EID: 24944445019     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505474102     Document Type: Article

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