Coformer selection based on degradation pathway of drugs: A case study of adefovir dipivoxil-saccharin and adefovir dipivoxil-nicotinamide cocrystals

International Journal of Pharmaceutics

Volumn 438, Issue 1-2, 2012, Pages 327-335

  Gao, Yuan ^a   Gao, Jing ^a   Liu, Ziling ^a   Kan, Hongliang ^a   Zu, Hui ^a   Sun, Wanjin ^a   Zhang, Jianjun ^a   Qian, Shuai ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adefovir dipivoxil; Cocrystal; Degradation pathway; Nicotinamide; Saccharin

Indexed keywords

ADEFOVIR DIPIVOXIL; NICOTINAMIDE; SACCHARIN;

ACIDITY; ALKALINITY; ARTICLE; DRUG DEGRADATION; DRUG SOLUBILITY; HYDROGEN BOND; PRIORITY JOURNAL; SOLID STATE;

ADENINE; ANTIVIRAL AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLIZATION; DRUG STABILITY; NIACINAMIDE; ORGANOPHOSPHONATES; POWDER DIFFRACTION; PRODRUGS; SACCHARIN; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

EID: 84867401728     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.09.027     Document Type: Article

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