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Volumn 5, Issue 3, 2005, Pages 1013-1021

Pharmaceutical cocrystallization: Engineering a remedy for caffeine hydration

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; GLUTARIC ACID; MALEIC ACID; MALONIC ACID; OXALIC ACID;

EID: 19944371772     PISSN: 15287483     EISSN: None     Source Type: Journal    
DOI: 10.1021/cg0496540     Document Type: Article
Times cited : (642)

References (46)
  • 24
    • 1042294609 scopus 로고    scopus 로고
    • Stahl, P. H., Wermuth, C. G., Eds.; Verlay Helvetica Chimica Acta & Wiley-VCH: Zurich
    • Stahl, P. H.; Wermuth, C. G. In Handbook of Pharmaceutical Salts; Stahl, P. H., Wermuth, C. G., Eds.; Verlay Helvetica Chimica Acta & Wiley-VCH: Zurich, 2002; pp 265-327.
    • (2002) Handbook of Pharmaceutical Salts , pp. 265-327
    • Stahl, P.H.1    Wermuth, C.G.2
  • 25
    • 0038653828 scopus 로고    scopus 로고
    • Merck & Co.: Whitehouse Station, NJ
    • The Merck Index; 13th ed.; Merck & Co.: Whitehouse Station, NJ, 2001.
    • (2001) The Merck Index; 13th Ed.
  • 31
    • 19944364138 scopus 로고    scopus 로고
    • note
    • O⋯H and N⋯H contact distances are defined as less than the sum of the van der Waals radii O 1.52, N 1.55, and H 1.20 Angstroms; C-N bond type defined as "any". A list of the refcodes obtained from the CSD search is provided as Supporting Information.
  • 41
    • 19944413611 scopus 로고    scopus 로고
    • note
    • O-H bond distances for the carboxylic acid that bonds to the caffeine in each cocrystal structure are as follows, in angstroms: A - 0.97(2); B - 1.04(3); D - 1.06(2); E - 0.99(2); F - 0.92(3).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.