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Volumn 10, Issue 5, 2010, Pages 2229-2238

Polymorphs and solvates of a cocrystal involving an analgesic drug, ethenzamide, and 3,5-dinitrobenzoic acid

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EID: 77952014654     PISSN: 15287483     EISSN: 15287505     Source Type: Journal    
DOI: 10.1021/cg9015178     Document Type: Article
Times cited : (118)

References (66)
  • 5
    • 77952054009 scopus 로고    scopus 로고
    • Updated list of GRAS chemicals may be downloaded from
    • Updated list of GRAS chemicals may be downloaded from http://www.cfsan.fda.gov/dms/eafus.html.
  • 40
    • 77952077902 scopus 로고    scopus 로고
    • May 2009 update; Cambridge Crystallographic Data Centre, Cambridge. U.K.,; to be found under
    • Cambridge Structural Database (version 5.29) ConQuest 1.10, May 2009 update; Cambridge Crystallographic Data Centre, Cambridge. U.K., 2007; to be found under www.ccdc.cam.ac.uk.
    • (2007) Cambridge Structural Database (Version 5.29) ConQuest 1.10
  • 42
    • 77952038457 scopus 로고    scopus 로고
    • It should be mentioned here that the CSD does not contain information pertaining to pharmaceutical relevance of many cocrystal components, and it is often difficult to judge whether a particular compound is pharmaceutically relevant or not just based on its compound name. Hence, our estimation of pharmaceutical cocrystals is based on a general search of all these compounds, and it is possible that the actual number of pharmaceutical cocrystals could be more than 137 of the total 3624 cocrystals
    • It should be mentioned here that the CSD does not contain information pertaining to pharmaceutical relevance of many cocrystal components, and it is often difficult to judge whether a particular compound is pharmaceutically relevant or not just based on its compound name. Hence, our estimation of pharmaceutical cocrystals is based on a general search of all these compounds, and it is possible that the actual number of pharmaceutical cocrystals could be more than 137 of the total 3624 cocrystals.
  • 44
    • 77952071864 scopus 로고    scopus 로고
    • Computed in Materials Studio using Forcite module, COMPAS force field
    • Computed in Materials Studio using Forcite module, COMPAS force field. www.accelrys.com.
  • 65
    • 27944487022 scopus 로고    scopus 로고
    • As part of an analysis of the occurrence of pharmaceutically acceptable anions and cations in the CSD, Haynes et al. retrieved the hydrates of cocrystals that contain at least one pharmaceutically acceptable acid or base. It was found that, of the 381 total cocrystals, 59 (15.5%) were hydrates. See
    • As part of an analysis of the occurrence of pharmaceutically acceptable anions and cations in the CSD, Haynes et al. retrieved the hydrates of cocrystals that contain at least one pharmaceutically acceptable acid or base. It was found that, of the 381 total cocrystals, 59 (15.5%) were hydrates. See Haynes, D. A.; Jones, W.; Motherwell, W. D. S. J. Pharm. Sci. 2005, 94, 2111
    • (2005) J. Pharm. Sci. , vol.94 , pp. 2111
    • Haynes, D.A.1    Jones, W.2    Motherwell, W.D.S.3
  • 66
    • 77952087116 scopus 로고    scopus 로고
    • note
    • 2+, COOÂ etc., significantly increases the chances of forming hydrates (see refs 63 and 65).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.