Metabolite discovery of helicidum in rat urine with XCMS based on the data of ultra performance liquid chromatography coupled to time-of-flight mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 907, Issue , 2012, Pages 146-153

  Liu, Qingfei ^a   Shi, Yun ^b   Guo, Tuo ^c   Wang, Yong ^a   Cong, Wenjuan ^d   Zhu, Jingjie ^a  

^a Tsinghua University   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^c GUILIN UNIVERSITY OF ELECTRONIC TECHNOLOGY   (China)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Helicidum; Metabolites; UPLC TOF MS; Urine; XCMS

Indexed keywords

ACTIVE COMPONENTS; CHROMATOGRAPHIC PEAKS; GLUCURONIDES; HELICIDUM; HIGH EFFICACY; IN-VIVO; MOLECULAR FORMULA; OPEN-SOURCE SOFTWARES; ORAL ADMINISTRATION; PARENT COMPOUNDS; RAT URINE; SIDE EFFECT; TIME OF FLIGHT MASS SPECTROMETRY; TIME-OF-FLIGHT MS; TRIGEMINAL NEURALGIA; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY; UPLC/TOF MS; URINE; URINE EXCRETION; URINE SAMPLE; VASCULAR HEADACHES; XCMS;

ACETYLATION; ALKYLATION; BIOINFORMATICS; BODY FLUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; METHYLATION; OXIDATION; RATS;

BIOMOLECULES;

DRUG METABOLITE; HELICIDUM; PYRANOSIDE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DRUG EXCRETION; DRUG METABOLISM; DRUG URINE LEVEL; ION CURRENT; LIMIT OF QUANTITATION; MALE; METHYLATION; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; ROOM TEMPERATURE; SIGNAL NOISE RATIO; SINGLE DRUG DOSE; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTATIONAL BIOLOGY; LINEAR MODELS; MALE; MASS SPECTROMETRY; MONOSACCHARIDES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOFTWARE;

HELICIDAE; RATTUS;

EID: 84867401308     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.09.029     Document Type: Article

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