The cytotoxicity of oxalate, metabolite of ethylene glycol, is due to calcium oxalate monohydrate formation

Toxicology

Volumn 208, Issue 3, 2005, Pages 347-355

  Guo, Chungang ^a   McMartin, Kenneth E ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Calcium oxalate; Membrane damage; Oxalate crystals; Proximal tubular cells; Renal toxicity

Indexed keywords

EDETIC ACID; ETHYLENE GLYCOL; OXALIC ACID; WHEWELLITE;

ACIDOSIS; ACUTE TOXICITY; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL DEATH; COMPARATIVE TOXICOLOGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HEMOLYSIS; HUMAN; HUMAN CELL; KIDNEY INJURY; KIDNEY METABOLISM; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MEMBRANE DAMAGE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES COMPARISON; SPECIES DIFFERENCE; TOXICOKINETICS;

EID: 13444311654     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.11.029     Document Type: Article

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