Characterization of the antibody response elicited by immunization with pneumococcal surface protein A (PspA) as recombinant protein or DNA vaccine and analysis of protection against an intranasal lethal challenge with Streptococcus pneumoniae

Microbial Pathogenesis

Volumn 53, Issue 5-6, 2012, Pages 243-249

  Vadesilho, Cintia F M ^a   Ferreira, Daniela M ^a,c   Moreno, Adriana T ^a   Chavez Olortegui, Carlos ^b   Machado de Avila, Ricardo A ^b   Oliveira, Maria Leonor S ^a   Ho, Paulo L ^a   Miyaji, Eliane N ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UFMG   (Brazil)

^c LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

DNA vaccine; PspA; Streptococcus pneumoniae

Indexed keywords

ALUMINUM POTASSIUM SULFATE; DNA VACCINE; EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2A ANTIBODY; PNEUMOCOCCAL SURFACE PROTEIN A; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOREACTIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMID; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOCOCCUS PNEUMONIAE;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; EPITOPE MAPPING; FEMALE; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; RECOMBINANT PROTEINS; SURVIVAL ANALYSIS; VACCINATION; VACCINES, DNA; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 84867395054     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2012.08.007     Document Type: Article

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