메뉴 건너뛰기




Volumn 1270, Issue 1, 2012, Pages 112-119

Thymosin β4 sustained release from poly(lactide-co-glycolide) microspheres: Synthesis and implications for treatment of myocardial ischemia

Author keywords

Controlled; Heart; Microsphere; Release; Sustained; Thymosin 4

Indexed keywords

ALGINIC ACID; CHITOSAN; COLLAGEN; GELATIN; HEPARIN; MATRIX METALLOPROTEINASE; MICROSPHERE; ORGANIC SOLVENT; POLYGLACTIN; THYMOSIN BETA4;

EID: 84867362005     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06681.x     Document Type: Article
Times cited : (3)

References (59)
  • 1
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello, L.P., R.L. Avery, P.G. Arrigg, et al. 1994. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N. Engl. J. Med. 331: 1480-1487.
    • (1994) N. Engl. J. Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 2
    • 0035725781 scopus 로고    scopus 로고
    • Proteinuria in a placebo-controlled study of basic fibroblast growth factor for intermittent claudication
    • Cooper, L.T., Jr., W.R. Hiatt, M.A. Creager, et al. 2001. Proteinuria in a placebo-controlled study of basic fibroblast growth factor for intermittent claudication. Vasc. Med. 6: 235-239.
    • (2001) Vasc. Med. , vol.6 , pp. 235-239
    • Cooper Jr, L.T.1    Hiatt, W.R.2    Creager, M.A.3
  • 3
    • 34548267693 scopus 로고    scopus 로고
    • Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization
    • Jain, R.K., A.V. Finn, F.D. Kolodgie, et al. 2007. Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization. Nat. Clin. Pract. Cardiovasc. Med. 4: 491-502.
    • (2007) Nat. Clin. Pract. Cardiovasc. Med , vol.4 , pp. 491-502
    • Jain, R.K.1    Finn, A.V.2    Kolodgie, F.D.3
  • 4
    • 33846002305 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment
    • Lucerna, M., A. Zernecke, R. de Nooijer, et al. 2007. Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment. Blood 109: 122-129.
    • (2007) Blood , vol.109 , pp. 122-129
    • Lucerna, M.1    Zernecke, A.2    de Nooijer, R.3
  • 5
    • 26244463577 scopus 로고    scopus 로고
    • Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage
    • Virmani, R., F.D. Kolodgie, A.P. Burke, et al. 2005. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler. Thromb. Vasc. Biol. 25: 2054-2061.
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2054-2061
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3
  • 6
    • 22944447755 scopus 로고    scopus 로고
    • Transendocardial and transepicardial intramyocardial fibroblast growth factor-2 administration: myocardial and tissue distribution
    • Laham, R.J., M. Post, M. Rezaee, et al. 2005. Transendocardial and transepicardial intramyocardial fibroblast growth factor-2 administration: myocardial and tissue distribution. Drug Metab. Dispos. 33: 1101-1107.
    • (2005) Drug Metab. Dispos , vol.33 , pp. 1101-1107
    • Laham, R.J.1    Post, M.2    Rezaee, M.3
  • 7
    • 0030721619 scopus 로고    scopus 로고
    • Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution
    • Lazarous, D.F., M. Shou, J.A. Stiber, et al. 1997. Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution. Cardiovasc Res. 36: 78-85.
    • (1997) Cardiovasc Res , vol.36 , pp. 78-85
    • Lazarous, D.F.1    Shou, M.2    Stiber, J.A.3
  • 8
    • 0037564082 scopus 로고    scopus 로고
    • Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study
    • Fuchs, S., L.F. Satler, R. Kornowski, et al. 2003. Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study. J. Am. Coll. Cardiol. 41: 1721-1724.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 1721-1724
    • Fuchs, S.1    Satler, L.F.2    Kornowski, R.3
  • 9
    • 9644281738 scopus 로고    scopus 로고
    • Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
    • Bock-Marquette, I., A. Saxena, M.D. White, et al. 2004. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature 432: 466-472.
    • (2004) Nature , vol.432 , pp. 466-472
    • Bock-Marquette, I.1    Saxena, A.2    White, M.D.3
  • 10
    • 63549141609 scopus 로고    scopus 로고
    • Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo
    • Bock-Marquette, I., S. Shrivastava, G.C. Pipes, et al. 2009. Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J. Mol. Cell Cardiol. 46: 728-738.
    • (2009) J. Mol. Cell Cardiol. , vol.46 , pp. 728-738
    • Bock-Marquette, I.1    Shrivastava, S.2    Pipes, G.C.3
  • 11
    • 0037420108 scopus 로고    scopus 로고
    • Myocyte apoptosis: programming ventricular remodeling
    • Mani, K. & R.N. Kitsis. 2003. Myocyte apoptosis: programming ventricular remodeling. J. Am. Coll. Cardiol. 41: 761-764.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 761-764
    • Mani, K.1    Kitsis, R.N.2
  • 12
    • 0034048306 scopus 로고    scopus 로고
    • Cardiac remodeling by fibrous tissue after infarction in rats
    • Sun, Y., J.Q. Zhang, J. Zhang & S. Lamparter. 2000. Cardiac remodeling by fibrous tissue after infarction in rats. J. Lab. Clin. Med. 135: 316-323.
    • (2000) J. Lab. Clin. Med. , vol.135 , pp. 316-323
    • Sun, Y.1    Zhang, J.Q.2    Zhang, J.3    Lamparter, S.4
  • 13
    • 77951782307 scopus 로고    scopus 로고
    • Thymosin beta4 facilitates epicardial neovascularization of the injured adult heart
    • Smart, N., C.A. Risebro, J.E. Clark, et al. 2010. Thymosin beta4 facilitates epicardial neovascularization of the injured adult heart. Ann. N. Y. Acad. Sci. 1194: 97-104.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 97-104
    • Smart, N.1    Risebro, C.A.2    Clark, J.E.3
  • 14
    • 77954574668 scopus 로고    scopus 로고
    • Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke
    • Morris, D.C., M. Chopp, L. Zhang, et al. 2010. Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke. Neuroscience 169: 674-682.
    • (2010) Neuroscience , vol.169 , pp. 674-682
    • Morris, D.C.1    Chopp, M.2    Zhang, L.3
  • 15
    • 0031008409 scopus 로고    scopus 로고
    • Biodistribution of synthetic thymosin beta 4 in the serum, urine, and major organs of mice
    • Mora, C.A., C.A. Baumann, J.E. Paino, et al. 1997. Biodistribution of synthetic thymosin beta 4 in the serum, urine, and major organs of mice. Int. J. Immunopharmacol. 19: 1-8.
    • (1997) Int. J. Immunopharmacol , vol.19 , pp. 1-8
    • Mora, C.A.1    Baumann, C.A.2    Paino, J.E.3
  • 16
    • 0036194987 scopus 로고    scopus 로고
    • Incomplete retention after direct myocardial injection
    • Grossman, P.M., Z. Han, M. Palasis, et al. 2002. Incomplete retention after direct myocardial injection. Catheter Cardiovasc. Interv. 55: 392-397.
    • (2002) Catheter Cardiovasc. Interv , vol.55 , pp. 392-397
    • Grossman, P.M.1    Han, Z.2    Palasis, M.3
  • 17
    • 0036372952 scopus 로고    scopus 로고
    • Myocardial drug distribution pattern following intrapericardial delivery: an MRI analysis
    • Gleason, J.D., K.P. Nguyen, K.V. Kissinger, et al. 2002. Myocardial drug distribution pattern following intrapericardial delivery: an MRI analysis. J. Cardiovasc. Magn. Reson. 4: 311-316.
    • (2002) J. Cardiovasc. Magn. Reson , vol.4 , pp. 311-316
    • Gleason, J.D.1    Nguyen, K.P.2    Kissinger, K.V.3
  • 18
    • 0037371222 scopus 로고    scopus 로고
    • Intrapericardial administration of basic fibroblast growth factor: myocardial and tissue distribution and comparison with intracoronary and intravenous administration
    • Laham, R.J., M. Rezaee, M. Post, et al. 2003. Intrapericardial administration of basic fibroblast growth factor: myocardial and tissue distribution and comparison with intracoronary and intravenous administration. Catheter Cardiovasc. Interv. 58: 375-381.
    • (2003) Catheter Cardiovasc. Interv , vol.58 , pp. 375-381
    • Laham, R.J.1    Rezaee, M.2    Post, M.3
  • 19
    • 67650596617 scopus 로고    scopus 로고
    • Cell-responsive hydrogel for encapsulation of vascular cells
    • Kraehenbuehl, T.P., L.S. Ferreira, P. Zammaretti, et al. 2009. Cell-responsive hydrogel for encapsulation of vascular cells. Biomaterials 30: 4318-4324.
    • (2009) Biomaterials , vol.30 , pp. 4318-4324
    • Kraehenbuehl, T.P.1    Ferreira, L.S.2    Zammaretti, P.3
  • 20
    • 80054689971 scopus 로고    scopus 로고
    • Controlled-release of thymosin beta 4 using collagen-chitosan composite hydrogels promotes epicardial cell migration and angiogenesis
    • Chiu, L.L.Y. & M. Radisic. 2011. Controlled-release of thymosin beta 4 using collagen-chitosan composite hydrogels promotes epicardial cell migration and angiogenesis. J. Control. Release 155: 376-385.
    • (2011) J. Control. Release , vol.155 , pp. 376-385
    • Chiu, L.L.Y.1    Radisic, M.2
  • 21
    • 0037499581 scopus 로고    scopus 로고
    • Intramyocardial sustained delivery of basic fibroblast growth factor improves angiogenesis and ventricular function in a rat infarct model
    • Iwakura, A., M. Fujita, K. Kataoka, et al. 2003. Intramyocardial sustained delivery of basic fibroblast growth factor improves angiogenesis and ventricular function in a rat infarct model. Heart Vessels 18: 93-99.
    • (2003) Heart Vessels , vol.18 , pp. 93-99
    • Iwakura, A.1    Fujita, M.2    Kataoka, K.3
  • 22
    • 33744904758 scopus 로고    scopus 로고
    • Effects of basic fibroblast growth factor microspheres on angiogenesis in ischemic myocardium and cardiac function: analysis with dobutamine cardiovascular magnetic resonance tagging
    • Liu, Y., L. Sun, Y. Huan, et al. 2006. Effects of basic fibroblast growth factor microspheres on angiogenesis in ischemic myocardium and cardiac function: analysis with dobutamine cardiovascular magnetic resonance tagging. Eur. J. Cardiothorac. Surg. 30: 103-107.
    • (2006) Eur. J. Cardiothorac. Surg. , vol.30 , pp. 103-107
    • Liu, Y.1    Sun, L.2    Huan, Y.3
  • 23
    • 34249911703 scopus 로고    scopus 로고
    • Gelatin microspheres encapsulated with a nonpeptide angiogenic agent, ginsenoside Rg1, for intramyocardial injection in a rat model with infarcted myocardium
    • Wei, H.J., H.H. Yang, C.H. Chen, et al. 2007. Gelatin microspheres encapsulated with a nonpeptide angiogenic agent, ginsenoside Rg1, for intramyocardial injection in a rat model with infarcted myocardium. J. Control Release 120: 27-34.
    • (2007) J. Control Release , vol.120 , pp. 27-34
    • Wei, H.J.1    Yang, H.H.2    Chen, C.H.3
  • 24
    • 0035022294 scopus 로고    scopus 로고
    • Intramyocardial delivery of basic fibroblast growth factor-impregnated gelatin hydrogel microspheres enhances collateral circulation to infarcted canine myocardium
    • Yamamoto, T., N. Suto, T. Okubo, et al. 2001. Intramyocardial delivery of basic fibroblast growth factor-impregnated gelatin hydrogel microspheres enhances collateral circulation to infarcted canine myocardium. Jpn Circ. J. 65: 439-444.
    • (2001) Jpn Circ. J. , vol.65 , pp. 439-444
    • Yamamoto, T.1    Suto, N.2    Okubo, T.3
  • 25
    • 31044453148 scopus 로고    scopus 로고
    • Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers
    • Hsieh, P.C., M.E. Davis, J. Gannon, et al. 2006. Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. J. Clin. Invest. 116: 237-248.
    • (2006) J. Clin. Invest , vol.116 , pp. 237-248
    • Hsieh, P.C.1    Davis, M.E.2    Gannon, J.3
  • 26
    • 34249933136 scopus 로고    scopus 로고
    • Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction
    • Hao, X., E.A. Silva, A. Mansson-Broberg, et al. 2007. Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction. Cardiovasc. Res. 75: 178-185.
    • (2007) Cardiovasc. Res. , vol.75 , pp. 178-185
    • Hao, X.1    Silva, E.A.2    Mansson-Broberg, A.3
  • 27
    • 0033517733 scopus 로고    scopus 로고
    • Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial
    • Laham, R.J., F.W. Sellke, E.R. Edelman, et al. 1999. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial. Circulation 100: 1865-1871.
    • (1999) Circulation , vol.100 , pp. 1865-1871
    • Laham, R.J.1    Sellke, F.W.2    Edelman, E.R.3
  • 28
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Jain, R.A. 2000. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21: 2475-2490.
    • (2000) Biomaterials , vol.21 , pp. 2475-2490
    • Jain, R.A.1
  • 29
    • 0027169876 scopus 로고
    • Determinants of release rate of tetanus vaccine from polyester microspheres
    • Alonso, M.J., S. Cohen, T.G. Park, et al. 1993. Determinants of release rate of tetanus vaccine from polyester microspheres. Pharm. Res. 10: 945-953.
    • (1993) Pharm. Res , vol.10 , pp. 945-953
    • Alonso, M.J.1    Cohen, S.2    Park, T.G.3
  • 30
    • 0030339449 scopus 로고    scopus 로고
    • Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine
    • Schwendeman, S.P., H.R. Costantino, R.K. Gupta, et al. 1996. Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine. Dev. Biol. Stand. 87: 293-306.
    • (1996) Dev. Biol. Stand , vol.87 , pp. 293-306
    • Schwendeman, S.P.1    Costantino, H.R.2    Gupta, R.K.3
  • 31
    • 0026628154 scopus 로고
    • Sustained release of nerve growth factor from biodegradable polymer microspheres
    • Camarata, P.J., R. Suryanarayanan, D.A. Turner, et al. 1992. Sustained release of nerve growth factor from biodegradable polymer microspheres. Neurosurgery 30: 313-319.
    • (1992) Neurosurgery , vol.30 , pp. 313-319
    • Camarata, P.J.1    Suryanarayanan, R.2    Turner, D.A.3
  • 32
    • 0035858370 scopus 로고    scopus 로고
    • Development of poly-(D,L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
    • Cleland, J.L., E.T. Duenas, A. Park, et al. 2001. Development of poly-(D, L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J. Control Release 72: 13-24.
    • (2001) J. Control Release , vol.72 , pp. 13-24
    • Cleland, J.L.1    Duenas, E.T.2    Park, A.3
  • 33
    • 0034048197 scopus 로고    scopus 로고
    • Effect of the concurrent LHRH antagonist administration with a LHRH superagonist in rats
    • Kostanski, J.W., B.A. Dani, B. Schrier & P.P. DeLuca. 2000. Effect of the concurrent LHRH antagonist administration with a LHRH superagonist in rats. Pharm. Res. 17: 445-450.
    • (2000) Pharm. Res , vol.17 , pp. 445-450
    • Kostanski, J.W.1    Dani, B.A.2    Schrier, B.3    DeLuca, P.P.4
  • 34
    • 0028029215 scopus 로고
    • Preparation of three-month depot injectable microspheres of leuprorelin acetate using biodegradable polymers
    • Okada, H., Y. Doken, Y. Ogawa & H. Toguchi. 1994. Preparation of three-month depot injectable microspheres of leuprorelin acetate using biodegradable polymers. Pharm. Res. 11: 1143-1147.
    • (1994) Pharm. Res. , vol.11 , pp. 1143-1147
    • Okada, H.1    Doken, Y.2    Ogawa, Y.3    Toguchi, H.4
  • 35
    • 0030061447 scopus 로고    scopus 로고
    • Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers.
    • Athanasiou, K.A., G.G. Niederauer & C.M. Agrawal. 1996. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 17: 93-102.
    • (1996) Biomaterials , vol.17 , pp. 93-102
    • Athanasiou, K.A.1    Niederauer, G.G.2    Agrawal, C.M.3
  • 36
    • 0037619257 scopus 로고    scopus 로고
    • Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility
    • Fournier, E., C. Passirani, C.N. Montero-Menei & J.P. Benoit. 2003. Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility. Biomaterials 24: 3311-3331.
    • (2003) Biomaterials , vol.24 , pp. 3311-3331
    • Fournier, E.1    Passirani, C.2    Montero-Menei, C.N.3    Benoit, J.P.4
  • 38
    • 0242352380 scopus 로고    scopus 로고
    • Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration
    • Carrascosa, C., I. Torres-Aleman, C. Lopez-Lopez, et al. 2004. Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration. Biomaterials 25: 707-714.
    • (2004) Biomaterials , vol.25 , pp. 707-714
    • Carrascosa, C.1    Torres-Aleman, I.2    Lopez-Lopez, C.3
  • 39
    • 0035914222 scopus 로고    scopus 로고
    • Protein release microparticles based on the blend of poly(D,L-lactic-co-glycolic acid) and oligo-ethylene glycol grafted poly(L-lactide)
    • Cho, K.Y., S.H. Choi, C.H. Kim, et al. 2001. Protein release microparticles based on the blend of poly(D, L-lactic-co-glycolic acid) and oligo-ethylene glycol grafted poly(L-lactide). J. Control Release 76: 275-284.
    • (2001) J. Control Release , vol.76 , pp. 275-284
    • Cho, K.Y.1    Choi, S.H.2    Kim, C.H.3
  • 40
    • 0032969939 scopus 로고    scopus 로고
    • Determination of the internal morphology of poly (D,L-lactide) microspheres using stereological methods
    • Ehtezazi, T., C. Washington & C.D. Melia. 1999. Determination of the internal morphology of poly (D, L-lactide) microspheres using stereological methods. J. Control Release 57: 301-314.
    • (1999) J. Control Release , vol.57 , pp. 301-314
    • Ehtezazi, T.1    Washington, C.2    Melia, C.D.3
  • 41
    • 0034602127 scopus 로고    scopus 로고
    • Influence of the co-encapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres
    • Rosa, G.D., R. Iommelli, M.I. La Rotonda, et al. 2000. Influence of the co-encapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres. J. Control Release 69: 283-295.
    • (2000) J. Control Release , vol.69 , pp. 283-295
    • Rosa, G.D.1    Iommelli, R.2    La Rotonda, M.I.3
  • 42
    • 0006371520 scopus 로고    scopus 로고
    • Biodegradable polyesters for medical and ecological applications
    • Ikada, Y. & H. Tsuji. 2000. Biodegradable polyesters for medical and ecological applications. Macromol Rapid Comm. 21: 117-132.
    • (2000) Macromol Rapid Comm. , vol.21 , pp. 117-132
    • Ikada, Y.1    Tsuji, H.2
  • 43
    • 3042856516 scopus 로고    scopus 로고
    • Comparative study on sustained release of human growth hormone from semi-crystalline poly(L-lactic acid) and amorphous poly(D,L-lactic-co-glycolic acid) microspheres: morphological effect on protein release
    • Kim, H.K. & T.G. Park. 2004. Comparative study on sustained release of human growth hormone from semi-crystalline poly(L-lactic acid) and amorphous poly(D, L-lactic-co-glycolic acid) microspheres: morphological effect on protein release. J. Control Release 98: 115-125.
    • (2004) J. Control Release , vol.98 , pp. 115-125
    • Kim, H.K.1    Park, T.G.2
  • 44
    • 24944566791 scopus 로고    scopus 로고
    • Preparation and characterization of melittin-loaded poly (DL-lactic acid) or poly(DL-lactic-co-glycolic acid) microspheres made by the double emulsion method
    • Cui, F., D. Cun, A. Tao, et al. 2005. Preparation and characterization of melittin-loaded poly (DL-lactic acid) or poly(DL-lactic-co-glycolic acid) microspheres made by the double emulsion method. J. Control Release 107: 310-319.
    • (2005) J. Control Release , vol.107 , pp. 310-319
    • Cui, F.1    Cun, D.2    Tao, A.3
  • 45
    • 0032484235 scopus 로고    scopus 로고
    • NGF release from poly(D,L-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability
    • Pean, J.M., M.C. Venier-Julienne, F. Boury, et al. 1998. NGF release from poly(D, L-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. J. Control Release 56: 175-187.
    • (1998) J. Control Release , vol.56 , pp. 175-187
    • Pean, J.M.1    Venier-Julienne, M.C.2    Boury, F.3
  • 46
    • 0142195953 scopus 로고    scopus 로고
    • The release profiles and bioactivity of parathyroid hormone from poly(lactic-co-glycolic acid) microspheres
    • Wei, G., G.J. Pettway, L.K. McCauley & P.X. Ma. 2004. The release profiles and bioactivity of parathyroid hormone from poly(lactic-co-glycolic acid) microspheres. Biomaterials 25: 345-352.
    • (2004) Biomaterials , vol.25 , pp. 345-352
    • Wei, G.1    Pettway, G.J.2    McCauley, L.K.3    Ma, P.X.4
  • 47
    • 0032917367 scopus 로고    scopus 로고
    • One-month sustained release microspheres of 125I-bovine calcitonin. In vitro-in vivo studies
    • Diaz, R.V., M. Llabres & C. Evora. 1999. One-month sustained release microspheres of 125I-bovine calcitonin. In vitro-in vivo studies. J. Control Release 59: 55-62.
    • (1999) J. Control Release , vol.59 , pp. 55-62
    • Diaz, R.V.1    Llabres, M.2    Evora, C.3
  • 48
    • 0030867627 scopus 로고    scopus 로고
    • Microparticles of poly(dl-lactic-co-glycolic acid)/poly(ethylene glycol) blends for controlled drug delivery
    • Cleek, R., K. Ting, S.G. Eskin & A. Mikos. 1997. Microparticles of poly(dl-lactic-co-glycolic acid)/poly(ethylene glycol) blends for controlled drug delivery. J. Control Release. 48: 259-268.
    • (1997) J. Control Release , vol.48 , pp. 259-268
    • Cleek, R.1    Ting, K.2    Eskin, S.G.3    Mikos, A.4
  • 49
    • 0037028031 scopus 로고    scopus 로고
    • Effects of material hydrophobicity on physical properties of polymeric microspheres formed by double emulsion process
    • Ruan, G., S.S. Feng & Q.T. Li. 2002. Effects of material hydrophobicity on physical properties of polymeric microspheres formed by double emulsion process. J. Control Release 84: 151-160.
    • (2002) J. Control Release , vol.84 , pp. 151-160
    • Ruan, G.1    Feng, S.S.2    Li, Q.T.3
  • 50
    • 33745265629 scopus 로고    scopus 로고
    • Microsphere-integrated collagen scaffolds for tissue engineering: effect of microsphere formulation and scaffold properties on protein release kinetics
    • Ungaro, F., M. Biondi, I. d'Angelo, et al. 2006. Microsphere-integrated collagen scaffolds for tissue engineering: effect of microsphere formulation and scaffold properties on protein release kinetics. J. Control Release 113: 128-136.
    • (2006) J. Control Release , vol.113 , pp. 128-136
    • Ungaro, F.1    Biondi, M.2    d'Angelo, I.3
  • 51
    • 34248658536 scopus 로고    scopus 로고
    • Stabilization of recombinant human growth hormone against emulsification-induced aggregation by Pluronic surfactants during microencapsulation
    • Wei, G., L.F. Lu & W.Y. Lu. 2007. Stabilization of recombinant human growth hormone against emulsification-induced aggregation by Pluronic surfactants during microencapsulation. Int. J. Pharm. 338: 125-132.
    • (2007) Int. J. Pharm. , vol.338 , pp. 125-132
    • Wei, G.1    Lu, L.F.2    Lu, W.Y.3
  • 52
    • 0019864937 scopus 로고
    • Trapping and intramyocardial distribution of microspheres with different diameters in cat and rabbit hearts in vitro
    • Hof, R.P., A. Hof, R. Salzmann & F. Wyler. 1981. Trapping and intramyocardial distribution of microspheres with different diameters in cat and rabbit hearts in vitro. Basic Res. Cardiol. 76: 630-638.
    • (1981) Basic Res. Cardiol , vol.76 , pp. 630-638
    • Hof, R.P.1    Hof, A.2    Salzmann, R.3    Wyler, F.4
  • 53
    • 0029256583 scopus 로고
    • Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence
    • Grizzi, I., H. Garreau, S. Li & M. Vert. 1995. Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence. Biomaterials 16: 305-311.
    • (1995) Biomaterials , vol.16 , pp. 305-311
    • Grizzi, I.1    Garreau, H.2    Li, S.3    Vert, M.4
  • 54
    • 0028564916 scopus 로고
    • Biodegradation of PLA/GA polymers: increasing complexity
    • Vert, M., J. Mauduit & S. Li. 1994. Biodegradation of PLA/GA polymers: increasing complexity. Biomaterials 15: 1209-1213.
    • (1994) Biomaterials , vol.15 , pp. 1209-1213
    • Vert, M.1    Mauduit, J.2    Li, S.3
  • 55
    • 11444264292 scopus 로고    scopus 로고
    • Potentiometric method for determination of microclimate pH in Poly(lactic-co-glycolic acid) films
    • Shenderova, A., A. Ding & S. Schwendeman. 2004. Potentiometric method for determination of microclimate pH in Poly(lactic-co-glycolic acid) films. Macromolecules 37: 10052-10058.
    • (2004) Macromolecules , vol.37 , pp. 10052-10058
    • Shenderova, A.1    Ding, A.2    Schwendeman, S.3
  • 56
    • 0036175670 scopus 로고    scopus 로고
    • Peptide acylation by poly(alpha-hydroxy esters)
    • Lucke, A., J. Kiermaier & A. Gopferich. 2002. Peptide acylation by poly(alpha-hydroxy esters). Pharm. Res. 19: 175-181.
    • (2002) Pharm. Res. , vol.19 , pp. 175-181
    • Lucke, A.1    Kiermaier, J.2    Gopferich, A.3
  • 57
    • 67649103532 scopus 로고    scopus 로고
    • A new class of inhibitors of peptide sorption and acylation in PLGA
    • Sophocleous, A.M., Y. Zhang & S.P. Schwendeman. 2009. A new class of inhibitors of peptide sorption and acylation in PLGA. J. Control Release 137: 179-184.
    • (2009) J. Control Release , vol.137 , pp. 179-184
    • Sophocleous, A.M.1    Zhang, Y.2    Schwendeman, S.P.3
  • 58
    • 0021383294 scopus 로고
    • Transmural pH gradient in canine myocardial ischemia
    • Watson, R.M., D.R. Markle, et al. 1984. Transmural pH gradient in canine myocardial ischemia. Am. J. Physiol. 246: H232-H238.
    • (1984) Am. J. Physiol , vol.246
    • Watson, R.M.1    Markle, D.R.2
  • 59
    • 34548766577 scopus 로고    scopus 로고
    • Oxidative stress and cardiac repair/remodeling following infarction
    • Sun, Y. 2007. Oxidative stress and cardiac repair/remodeling following infarction. Am. J. Med. Sci. 334: 197-205.
    • (2007) Am. J. Med. Sci , vol.334 , pp. 197-205
    • Sun, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.