메뉴 건너뛰기




Volumn 1482, Issue , 2012, Pages 22-31

Morg1+/- heterozygous mice are protected from experimentally induced focal cerebral ischemia

Author keywords

Cerebral ischemia; Hypoxia inducible transcription factor (HIF); Middle cerebral artery occlusion (MCAO) model; Morg1; Prolyl hydroxylases; Stroke

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MESSENGER RNA; MORG1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 84867334170     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.09.017     Document Type: Article
Times cited : (15)

References (32)
  • 3
    • 34250832041 scopus 로고    scopus 로고
    • Differential regulation of toll-like receptor 4 gene expression in renal cells by angiotensin II: Dependence of AP1 and PU1 transcriptional sites
    • T. Bondeva, T. Roger, and G. Wolf Differential regulation of toll-like receptor 4 gene expression in renal cells by angiotensin II: dependence of AP1 and PU1 transcriptional sites Am. J. Nephrol. 27 2007 308 314
    • (2007) Am. J. Nephrol. , vol.27 , pp. 308-314
    • Bondeva, T.1    Roger, T.2    Wolf, G.3
  • 4
    • 33748714735 scopus 로고    scopus 로고
    • The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
    • J.C. Chavez, O. Baranova, J. Lin, and P. Pichiule The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes J. Neurosci. 26 2006 9471 9481
    • (2006) J. Neurosci. , vol.26 , pp. 9471-9481
    • Chavez, J.C.1    Baranova, O.2    Lin, J.3    Pichiule, P.4
  • 5
    • 77953512054 scopus 로고    scopus 로고
    • Suppression of hypoxia-inducible factor-1α and its downstream genes reduces acute hyperglycemia-enhanced hemorrhagic transformation in a rat model of cerebral ischemia
    • C. Chen, R.P. Ostrowski, C. Zhou, J. Tang, and J.H. Zhang Suppression of hypoxia-inducible factor-1α and its downstream genes reduces acute hyperglycemia-enhanced hemorrhagic transformation in a rat model of cerebral ischemia J. Neurosci. Res. 88 2010 2046 2055
    • (2010) J. Neurosci. Res. , vol.88 , pp. 2046-2055
    • Chen, C.1    Ostrowski, R.P.2    Zhou, C.3    Tang, J.4    Zhang, J.H.5
  • 6
    • 63449105562 scopus 로고    scopus 로고
    • Reduced Morg1 expression in ischemic human brain
    • D. Haase, S. Keiner, C. Mawrin, and G. Wolf Reduced Morg1 expression in ischemic human brain Neurosci. Lett. 455 2009 46 50
    • (2009) Neurosci. Lett. , vol.455 , pp. 46-50
    • Haase, D.1    Keiner, S.2    Mawrin, C.3    Wolf, G.4
  • 7
    • 70350705956 scopus 로고    scopus 로고
    • Morg1 heterozygous mice are protected from acute renal ischemia-reperfusion injury
    • E. Hammerschmidt, I. Loeffler, and G. Wolf Morg1 heterozygous mice are protected from acute renal ischemia-reperfusion injury Am. J. Physiol. Renal Physiol. 297 2009 F1273 F1287
    • (2009) Am. J. Physiol. Renal Physiol. , vol.297
    • Hammerschmidt, E.1    Loeffler, I.2    Wolf, G.3
  • 8
    • 33646852807 scopus 로고    scopus 로고
    • The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3)
    • U. Hopfer, H. Hopfer, K. Jablonski, R.A.K. Stahl, and G. Wolf The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3) J. Biol. Chem. 281 2006 8645 8655
    • (2006) J. Biol. Chem. , vol.281 , pp. 8645-8655
    • Hopfer, U.1    Hopfer, H.2    Jablonski, K.3    Stahl, R.A.K.4    Wolf, G.5
  • 9
    • 65749109731 scopus 로고    scopus 로고
    • Hypoxia-specific gene expression for ischemic disease gene therapy
    • H.A. Kim, R.I. Mahato, and M. Lee Hypoxia-specific gene expression for ischemic disease gene therapy Adv. Drug Delivery Rev. 61 2009 614 622
    • (2009) Adv. Drug Delivery Rev. , vol.61 , pp. 614-622
    • Kim, H.A.1    Mahato, R.I.2    Lee, M.3
  • 12
    • 31344460428 scopus 로고    scopus 로고
    • Progress in the identification of stroke-related genes: Emerging new possibilities to develop concepts in stroke therapy
    • A. Lippoldt, A. Reichel, and U. Moenning Progress in the identification of stroke-related genes: emerging new possibilities to develop concepts in stroke therapy CNS Drugs 19 2005 821 832
    • (2005) CNS Drugs , vol.19 , pp. 821-832
    • Lippoldt, A.1    Reichel, A.2    Moenning, U.3
  • 13
    • 0035895928 scopus 로고    scopus 로고
    • SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons
    • E.A. Lipscomb, P.D. Sarmiere, and R.S. Freeman SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons J. Biol. Chem. 276 2001 5085 5091
    • (2001) J. Biol. Chem. , vol.276 , pp. 5085-5091
    • Lipscomb, E.A.1    Sarmiere, P.D.2    Freeman, R.S.3
  • 14
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t) method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t) method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 15
    • 36248945117 scopus 로고    scopus 로고
    • Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation
    • D.J. Lomb, J.A. Straub, and R.S. Freeman Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation J. Neurochem. 103 2007 1897 1906
    • (2007) J. Neurochem. , vol.103 , pp. 1897-1906
    • Lomb, D.J.1    Straub, J.A.2    Freeman, R.S.3
  • 16
    • 0033902012 scopus 로고    scopus 로고
    • Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia
    • H.J.H. Marti, M. Bernaudin, A. Bellail, H. Schoch, M. Euler, E. Petit, and W. Risau Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia Am. J. Pathol 156 2000 965 976
    • (2000) Am. J. Pathol , vol.156 , pp. 965-976
    • Marti, H.J.H.1    Bernaudin, M.2    Bellail, A.3    Schoch, H.4    Euler, M.5    Petit, E.6    Risau, W.7
  • 17
    • 79952116549 scopus 로고    scopus 로고
    • Reperfusion therapies for acute ischemic stroke
    • C.A. Molina Reperfusion therapies for acute ischemic stroke Stroke 42 Suppl. 1 2011 S16 S19
    • (2011) Stroke , vol.42 , Issue.SUPPL. 1
    • Molina, C.A.1
  • 18
    • 62849087045 scopus 로고    scopus 로고
    • Identification of ischemic regions in a rat model of stroke
    • 10.1371/journal.pone.0004764
    • A. Popp, N. Jaenisch, O.W. Witte, and C. Frahm Identification of ischemic regions in a rat model of stroke PLoS One 4 2009 e4764 10.1371/journal.pone. 0004764
    • (2009) PLoS One , vol.4 , pp. 4764
    • Popp, A.1    Jaenisch, N.2    Witte, O.W.3    Frahm, C.4
  • 21
    • 77049093737 scopus 로고    scopus 로고
    • Inter-age variability of bona fide unvaried transcripts normalization of quantitative PCR data in ischemic stroke
    • M.W. Sieber, M. Guenther, M. Kohl, O.W. Witte, R.A. Claus, and C. Frahm Inter-age variability of bona fide unvaried transcripts normalization of quantitative PCR data in ischemic stroke Neurobiol. Aging 31 2010 654 664
    • (2010) Neurobiol. Aging , vol.31 , pp. 654-664
    • Sieber, M.W.1    Guenther, M.2    Kohl, M.3    Witte, O.W.4    Claus, R.A.5    Frahm, C.6
  • 22
    • 80054766188 scopus 로고    scopus 로고
    • Attenuated inflammatory response in aged mice brains following stroke
    • M.W. Sieber, R.A. Claus, O.W. Witte, and C. Frahm Attenuated inflammatory response in aged mice brains following stroke PLoS One 6 2011 e26288
    • (2011) PLoS One , vol.6 , pp. 26288
    • Sieber, M.W.1    Claus, R.A.2    Witte, O.W.3    Frahm, C.4
  • 24
    • 34249907554 scopus 로고    scopus 로고
    • Transcriptional regulation of neurogenesis: Potential mechanisms in cerebral ischemia
    • M.N. Schölzke, and M. Schwaninger Transcriptional regulation of neurogenesis: potential mechanisms in cerebral ischemia J. Mol. Med. 85 2007 577 588
    • (2007) J. Mol. Med. , vol.85 , pp. 577-588
    • Schölzke, M.N.1    Schwaninger, M.2
  • 26
    • 77950939997 scopus 로고    scopus 로고
    • Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: Neuroprotective effect of FK506
    • K. Szydlowska, A. Gozdz, M. Dabrowski, M. Zawadzka, and B. Kaminska Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506 J. Neurochem. 113 2010 904 918
    • (2010) J. Neurochem. , vol.113 , pp. 904-918
    • Szydlowska, K.1    Gozdz, A.2    Dabrowski, M.3    Zawadzka, M.4    Kaminska, B.5
  • 27
    • 2342474379 scopus 로고    scopus 로고
    • Modular construction of a signaling scaffold: Morg1 interacts with components of the ERK cascade and links ERK signaling to specific agonists
    • T. Vomastek, H.J. Schaefferm, A. Tarcsafalvi, M.E. Smolkin, E.A. Bissonette, and M.J. Weber Modular construction of a signaling scaffold: Morg1 interacts with components of the ERK cascade and links ERK signaling to specific agonists Proc. Nat. Acad. Sci. U.S.A. 101 2004 6981 6986
    • (2004) Proc. Nat. Acad. Sci. U.S.A. , vol.101 , pp. 6981-6986
    • Vomastek, T.1    Schaefferm, H.J.2    Tarcsafalvi, A.3    Smolkin, M.E.4    Bissonette, E.A.5    Weber, M.J.6
  • 28
    • 4644355082 scopus 로고    scopus 로고
    • Angiotensin II induces hypoxia-inducible factor-1 alpha in PC 12 cells through a posttranscriptional mechanism: Role of AT2 receptors
    • G. Wolf, R. Schroeder, and R.A. Stahl Angiotensin II induces hypoxia-inducible factor-1 alpha in PC 12 cells through a posttranscriptional mechanism: role of AT2 receptors Am. J. Nephrol. 24 2004 415 421
    • (2004) Am. J. Nephrol. , vol.24 , pp. 415-421
    • Wolf, G.1    Schroeder, R.2    Stahl, R.A.3
  • 30
    • 79954594089 scopus 로고    scopus 로고
    • Selective inhibition of early-but not late-expressed Hif-1α is neuroprotective in rats after focal ischemic brain damage
    • S.H. Yeh, L.C. Ou, P.W. Gean, J.J. Hung, and W.C. Chnag Selective inhibition of early-but not late-expressed Hif-1α is neuroprotective in rats after focal ischemic brain damage Brain Pathol. 21 2011 249 262
    • (2011) Brain Pathol. , vol.21 , pp. 249-262
    • Yeh, S.H.1    Ou, L.C.2    Gean, P.W.3    Hung, J.J.4    Chnag, W.C.5
  • 31
    • 34250711706 scopus 로고    scopus 로고
    • Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage
    • J.H. Yi, S.W. Park, R. Kapadia, and R. Vemuganti Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage Neurochem. Int. 50 2007 1014 1027
    • (2007) Neurochem. Int. , vol.50 , pp. 1014-1027
    • Yi, J.H.1    Park, S.W.2    Kapadia, R.3    Vemuganti, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.