Suppression of hypoxia-inducible factor-1α and its downstream genes reduces acute hyperglycemia-enhanced hemorrhagic transformation in a rat model of cerebral ischemia

Journal of Neuroscience Research

Volumn 88, Issue 9, 2010, Pages 2046-2055

  Chen, Chunhua ^a,b   Ostrowski, Robert P ^a   Zhou, Changman ^b   Tang, Jiping ^a   Zhang, John H ^a,c  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c LOMA LINDA UNIVERSITY   (United States)

Author keywords

2ME2; Blood brain barrier; Dextrose; Focal cerebral ischemia; YC 1

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 2 METHOXYESTRADIOL; GELATINASE A; GELATINASE B; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CONTROLLED STUDY; HEMISPHERE; HISTOLOGY; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; WESTERN BLOTTING; ZYMOGRAPHY;

ACUTE DISEASE; ANIMALS; BRAIN; BRAIN ISCHEMIA; CENTRAL NERVOUS SYSTEM AGENTS; DISEASE MODELS, ANIMAL; ESTRADIOL; HYPERGLYCEMIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INDAZOLES; INFARCTION, MIDDLE CEREBRAL ARTERY; INTRACRANIAL HEMORRHAGES; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 77953512054     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22361     Document Type: Article

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