Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells

Journal of Immunology

Volumn 189, Issue 8, 2012, Pages 3838-3847

  Riou, Catherine ^a   Treurnicht, Florette ^a   Abrahams, Melissa Rose ^a   Mlisana, Koleka ^b,c   Liu, Michael K P ^d   Goonetilleke, Nilu ^d   Koup, Richard ^e   Roederer, Mario ^e   Karim, Salim Abdool ^b   De Bruyn, Guy ^f   Williamson, Carolyn ^a   Gray, Clive M ^a   Burgers, Wendy A ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e National Institute for Allergy and Infectious Disease   (United States)

^f UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CD45RO ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; VIRUS RNA;

ARTICLE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOMEGALOVIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS CELL INTERACTION; VIRUS IMMUNITY; VIRUS LOAD;

CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CHRONIC DISEASE; COHORT STUDIES; CYTOMEGALOVIRUS; EPITOPES, T-LYMPHOCYTE; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; PROSPECTIVE STUDIES;

EID: 84867325788     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201488     Document Type: Article

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