The distribution of phosphodiesterase 2A in the rat brain

Neuroscience

Volumn 226, Issue , 2012, Pages 145-155

  Stephenson, D T ^a   Coskran, T M ^a   Kelly, M P ^a   Kleiman, R J ^a   Morton, D ^a   O'Neill, S M ^a   Schmidt, C J ^a   Weinberg, R J ^b   Menniti, F S ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cortex; Hippocampus; Immunohistochemistry; PDE2A; Phosphodiesterase 2A; Striatum

Indexed keywords

BRAIN ENZYME; MESSENGER RNA; PHOSPHODIESTERASE; PHOSPHODIESTERASE 2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL POPULATION; CORPUS STRIATUM; DENDRITE; DENTATE GRANULE CELL; ENZYME LOCALIZATION; GENE EXPRESSION; GLOBUS PALLIDUS; HABENULA; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERNEURON; MEDIUM SPINY NEURON; NEOSTRIATUM; NERVE CELL; NERVE CELL NETWORK; NERVE ENDING; NERVE FIBER; NEUROMODULATION; NEUROPIL; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; RHOMBENCEPHALON; SUBSTANTIA NIGRA PARS RETICULATA;

ANIMALS; ANTISENSE ELEMENTS (GENETICS); AUTORADIOGRAPHY; BLOOD VESSELS; BRAIN; BRAIN MAPPING; CEREBRAL CORTEX; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; DENDRITES; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NEOSTRIATUM; NEURONS; PYRAMIDAL CELLS; RATS; RNA, MESSENGER; SPINAL CORD;

EID: 84867321327     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.09.011     Document Type: Article

References (42)

1. Albin R.L., Young A.B., Penney J.B. The functional anatomy of basal ganglia disorders. Trends Neurosci 1989, 12(10):366-375.
2. Bingham J., Sudarsanam S., Srinivasan S. Profiling human phosphodiesterase genes and splice isoforms. Biochem Biophys Res Commun 2006, 350(1):25-32.
3. Boess F.G., Hendrix M., van der Staay F.-J., Erb C., Schreiber R., van Staveren W., de Vente J., Prickaerts J., Blokland A., Koenig G. Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. Neuropharmacology 2004, 47(7):1081-1092.
4. Buckmaster P.S., Wenzel H.J., Kunkel D.D., Schwartzkroin P.A. Axon arbors and synaptic connections of hippocampal mossy cells in the rat in vivo. J Comp Neurol 1996, 366:270-292.
5. Conti M., Beavo J. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Ann Rev Biochem 2007, 76(1):481-511.
6. Domeklopacinska K., Strosznajder J. The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging. Brain Res 2008, 1216:68-77.
7. Feil R., Kleppisch T. NO/cGMP-dependent modulation of synaptic transmission. Pharmacology of neurotransmitter release 2008, 529-560. Springer-Verlag, Berlin, Heidelberg. T.C. Sudhof, K. Starke (Eds.).
8. Fowler C.D., Kenny P.J. Habenular signaling in nicotine reinforcement. Neuropsychopharmacology 2012, 37(1):306-307.
9. Herkenham M., Nauta W.J. Efferent connections of the habenular nuclei in the rat. J Comp Neurol 1979, 187(1):19-47.
10. Jones E.G., Hendry S.H.C. Basket cells. Cerebral cortex: cellular components of the cerebral cortex 1984, 309-334. Plenum Press, New York. A.J.E. Peters (Ed.).
11. Juilfs D., Soderling S., Burns F., Beavo J. Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs). Rev Physiol Biochem Pharmacol 1999, 135(1):67-104.
12. Kelly M.P. Putting together the pieces of phosphodiesterase distribution patterns in the brain: a jigsaw puzzle of cyclic nucleotide regulation. Phosphodiesterases in the CNS 2012, John Wiley & Sons, Inc., New York. N.J. Brandon, A.R. West (Eds.).
13. Kelly M.P., Deadwyler S.A. Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance. Neuroscience 2002, 110(4):617-626.
14. Kelly M.P., Logue S.F., Brennan J., Day J.P., Lakkaraju S., Jiang L., Zhong X., Tam M., Sukoff Rizzo S.J., Platt B.J., Dwyer J.M., Neal S., Pulito V.L., Agostino M.J., Grauer S.M., Navarra R.L., Kelley C., Comery T.A., Murrills R.J., Houslay M.D., Brandon N.J. Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes. Proc Natl Acad Sci U S A 2010, 107(18):8457-8462.
15. Lakics V., Karran E.H., Boess F.G. Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues. Neuropharmacology 2010, 59(6):367-374.
16. Lin D.T.S., Fretier P., Jiang C., Vincent S.R. Nitric oxide signaling via cGMP-stimulated phosphodiesterase in striatal neurons. Synapse 2010, 64(6):460-466.
17. Lynch MJ, Hill EV, Houslay MD (2006) Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling. In Current topics in developmental biology (Gerald PS, ed.), pp. 225-259. Academic Press.
18. MacFarland R., Zelus B., Beavo J. High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP- induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J Biol Chem 1991, 266(1):136-142.
19. Markram H., Toledo-Rodriguez M., Wang Y., Gupta A., Silberberg G., Wu C. Interneurons of the neocortical inhibitory system. Nat Rev Neurosci 2004, 5(10):793-807.
20. Masood A., Nadeem A., Mustafa S.J., O'Donnell J.M. Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice. J Pharmacol Exp Ther 2008, 326(2):369-379.
21. Masood A., Huang Y., Hajjhussein H., Xiao L., Li H., Wang W., Hamza A., Zhan C.G., O'Donnell J.M. Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. J Pharmacol Exp Ther 2009, 331(2):690-699.
22. Menniti F.S., Faraci W.S., Schmidt C.J. Phosphodiesterases in the CNS: targets for drug development. Nat Rev Drug Discov 2006, 5(8):660-670.
23. Nicoll R.A., Schmitz D. Synaptic plasticity at hippocampal mossy fibre synapses. Nat Rev Neurosci 2005, 6(11):863-876.
24. Omori K., Kotera J. Overview of PDEs and their regulation. Circ Res 2007, 100(3):309-327.
25. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1997, Academic Press, San Diego.
26. Reiner A., Hart N.M., Lei W., Deng Y. Corticostriatal projection neurons - dichotomous types and dichotomous functions. Front Neuroanat 2010, 4:142.
27. Repaske D.R., Corbin J.G., Conti M., Goy M.F. A cyclicGMP-stimulated cyclic nucleotide phosphodiesterase gene is highly expressed in the limbic system of the rat brain. Neuroscience 1993, 56:673-686.
28. Rodefer J.S., Saland S.K., Eckrich S.J. Selective phosphodiesterase inhibitors improve performance on the ED/ID cognitive task in rats. Neuropharmacology 2011, 62(3):1182-1190.
29. Rosman G.J., Martins T.J., Sonnenburg W.K., Beavo J.A., Ferguson K., Loughney K. Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase. Gene 1997, 191(1):89-95.
30. Russwurm C., Zoidl G., Koesling D., Russwurm M. Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes. J Biol Chem 2009, 284(38):25782-25790.
31. Rutten K., Prickaerts J., Hendrix M., Vanderstaay F., Sik A., Blokland A. Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors. Eur J Pharmacol 2007, 558(1-3):107-112.
32. Schmidt C.J. Phosphodiesterase inhibitors as potential cognition enhancing agents. Curr Top Med Chem 2010, 10:222-230.
33. Seeger T.F., Bartlett B., Coskran T.M., Culp J.S., James L.C., Krull D.L., Lanfear J., Ryan A.M., Schmidt C.J., Strick C.A., Varghese A.H., Williams R.D., Wylie P.G., Menniti F.S. Immunohistochemical localization of PDE10A in the rat brain. Brain Res 2003, 985(2):113-126.
34. Sonnenburg W.K., Mullaney P.J., Beavo J.A. Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. Identification and distribution of isozyme variants. J Biol Chem 1991, 266(26):17655-17661.
35. Stephenson DT, Coskran TM, Morton DG, Wilhelms MB, Ryan AM, Finley J, Nelson R, Tate BA, Menniti FS, Schmidt CJ, Kleiman RJ (2007) PDE2A is localized to amyloid plaques in human Alzheimer's disease brain and in transgenic amyloid overexpressing mice; Society for Neuroscience 37th Annual Meeting Nov. 3-7, 2007; San Diego, CA. p. 152. 110/Q116.
36. Stephenson D., Coskran T., Wilhelms M., Adamowicz W., O'Donnell M., Muravnick K., Menniti F., Kleiman R., Morton D. Immunohistochemical localization of PDE2A in multiple mammalian species. J Histochem Cytochem 2009, 57:933-949.
37. Stroop S., Beavo J. Structure and function studies of the cGMP-stimulated phosphodiesterase. J Biol Chem 1991, 266(35):23802-23809.
38. Threlfell S., Sammut S., Menniti F.S., Schmidt C.J., West A.R. Inhibition of phosphodiesterase 10A increases the responsiveness of striatal projection neurons to cortical stimulation. J Pharmacol Exp Ther 2009, 328(3):785-795.
39. Van Staveren W.C.G., Steinbusch H.W.M., Markerink-Van Ittersum M., Repaske D.R., Goy M.F., Kotera J., Omori K., Beavo J.A., De Vente J. MRNA expression patterns of the cGMP-hydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain. J Comp Neurol 2003, 467(4):566-580.
40. Wilson C.J. Basal ganglia. The synaptic organization of the brain 2004, 361-415. Oxford University Press, New York. 5th ed. G.M.G. Shepherd (Ed.).
41. Xie Z., Adamowicz W., Eldred W., Jakowski A., Kleiman R., Morton D., Stephenson D., Strick C., Williams R., Menniti F. Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. Neurosci 2006, 139(2):597-607.
42. Yang Q., Paskind M., Bolger G., Thompson W.J., Repaske D.R., Cutler L.S., Epstein P.M. A novel cyclicGMP stimulated phosphodiesterase from rat brain. Biochem Biophys Res Commun 1994, 205:1850-1858.