-
1
-
-
63649108380
-
The roles of TLRs, RLRs and NLRs in pathogen recognition
-
Kawai T, Akira S, (2009) The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 21: 317-337.
-
(2009)
Int Immunol
, vol.21
, pp. 317-337
-
-
Kawai, T.1
Akira, S.2
-
2
-
-
75549091673
-
The IL-1 family: regulators of immunity
-
Sims JE, Smith DE, (2010) The IL-1 family: regulators of immunity. Nat Rev Immunol 10: 89-102.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 89-102
-
-
Sims, J.E.1
Smith, D.E.2
-
3
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356: 768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
-
4
-
-
60749104683
-
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
-
Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G, (2009) The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10: 241-247.
-
(2009)
Nat Immunol
, vol.10
, pp. 241-247
-
-
Franchi, L.1
Eigenbrod, T.2
Munoz-Planillo, R.3
Nunez, G.4
-
5
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J, (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
6
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, et al. (2009) Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol 183: 787-791.
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
-
7
-
-
18644374105
-
Blocking IL-1 in systemic inflammation
-
Dinarello CA, (2005) Blocking IL-1 in systemic inflammation. J Exp Med 201: 1355-1359.
-
(2005)
J Exp Med
, vol.201
, pp. 1355-1359
-
-
Dinarello, C.A.1
-
8
-
-
0019171406
-
The nature and action of granulocyte-macrophage colony stimulating factors
-
Burgess AW, Metcalf D, (1980) The nature and action of granulocyte-macrophage colony stimulating factors. Blood 56: 947-958.
-
(1980)
Blood
, vol.56
, pp. 947-958
-
-
Burgess, A.W.1
Metcalf, D.2
-
9
-
-
32644479365
-
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know
-
Shi Y, Liu CH, Roberts AI, Das J, Xu G, et al. (2006) Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res 16: 126-133.
-
(2006)
Cell Res
, vol.16
, pp. 126-133
-
-
Shi, Y.1
Liu, C.H.2
Roberts, A.I.3
Das, J.4
Xu, G.5
-
10
-
-
46249090513
-
Colony-stimulating factors in inflammation and autoimmunity
-
Hamilton JA, (2008) Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 8: 533-544.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 533-544
-
-
Hamilton, J.A.1
-
12
-
-
34548225362
-
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta
-
Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, et al. (2007) NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 130: 918-931.
-
(2007)
Cell
, vol.130
, pp. 918-931
-
-
Greten, F.R.1
Arkan, M.C.2
Bollrath, J.3
Hsu, L.C.4
Goode, J.5
-
13
-
-
70249110860
-
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
-
Franchi L, Eigenbrod T, Nunez G, (2009) Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol 183: 792-796.
-
(2009)
J Immunol
, vol.183
, pp. 792-796
-
-
Franchi, L.1
Eigenbrod, T.2
Nunez, G.3
-
14
-
-
0027528798
-
Anticytokine strategies in the treatment of the systemic inflammatory response syndrome
-
Dinarello CA, Gelfand JA, Wolff SM, (1993) Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA 269: 1829-1835.
-
(1993)
JAMA
, vol.269
, pp. 1829-1835
-
-
Dinarello, C.A.1
Gelfand, J.A.2
Wolff, S.M.3
-
15
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, Franklin S, Herzog L, et al. (1995) Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80: 401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
-
16
-
-
71749120637
-
Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion
-
Becker CE, Creagh EM, O'Neill LA, (2009) Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion. J Biol Chem 284: 34531-34537.
-
(2009)
J Biol Chem
, vol.284
, pp. 34531-34537
-
-
Becker, C.E.1
Creagh, E.M.2
O'Neill, L.A.3
-
17
-
-
0033872019
-
The safety and efficacy of GM-CSF as an adjuvant in hepatitis B vaccination of chronic hemodialysis patients who have failed primary vaccination
-
Evans TG, Schiff M, Graves B, Agosti J, Barritt ML, et al. (2000) The safety and efficacy of GM-CSF as an adjuvant in hepatitis B vaccination of chronic hemodialysis patients who have failed primary vaccination. Clin Nephrol 54: 138-142.
-
(2000)
Clin Nephrol
, vol.54
, pp. 138-142
-
-
Evans, T.G.1
Schiff, M.2
Graves, B.3
Agosti, J.4
Barritt, M.L.5
-
18
-
-
0038826031
-
Current developments in cancer vaccines and cellular immunotherapy
-
Ribas A, Butterfield LH, Glaspy JA, Economou JS, (2003) Current developments in cancer vaccines and cellular immunotherapy. J Clin Oncol 21: 2415-2432.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2415-2432
-
-
Ribas, A.1
Butterfield, L.H.2
Glaspy, J.A.3
Economou, J.S.4
-
19
-
-
0034939849
-
Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine
-
Parker SE, Monteith D, Horton H, Hof R, Hernandez P, et al. (2001) Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine. Gene Ther 8: 1011-1023.
-
(2001)
Gene Ther
, vol.8
, pp. 1011-1023
-
-
Parker, S.E.1
Monteith, D.2
Horton, H.3
Hof, R.4
Hernandez, P.5
-
20
-
-
62949194424
-
Effect of immunological adjuvants: GM-CSF (granulocyte-monocyte colony stimulating factor) and IL-23 (interleukin-23) on immune responses generated against hepatitis C virus core DNA vaccine
-
Hartoonian C, Ebtekar M, Soleimanjahi H, Karami A, Mahdavi M, et al. (2009) Effect of immunological adjuvants: GM-CSF (granulocyte-monocyte colony stimulating factor) and IL-23 (interleukin-23) on immune responses generated against hepatitis C virus core DNA vaccine. Cytokine 46: 43-50.
-
(2009)
Cytokine
, vol.46
, pp. 43-50
-
-
Hartoonian, C.1
Ebtekar, M.2
Soleimanjahi, H.3
Karami, A.4
Mahdavi, M.5
-
21
-
-
22544458183
-
Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer
-
Beinart G, Rini BI, Weinberg V, Small EJ, (2005) Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer. Clin Prostate Cancer 4: 55-60.
-
(2005)
Clin Prostate Cancer
, vol.4
, pp. 55-60
-
-
Beinart, G.1
Rini, B.I.2
Weinberg, V.3
Small, E.J.4
-
22
-
-
0033697454
-
CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
-
Schulz O, Edwards AD, Schito M, Aliberti J, Manickasingham S, et al. (2000) CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 13: 453-462.
-
(2000)
Immunity
, vol.13
, pp. 453-462
-
-
Schulz, O.1
Edwards, A.D.2
Schito, M.3
Aliberti, J.4
Manickasingham, S.5
-
23
-
-
77954497180
-
Cutting edge: granulocyte-macrophage colony-stimulating factor is the major CD8+ T cell-derived licensing factor for dendritic cell activation
-
Min L, Mohammad Isa SA, Shuai W, Piang CB, Nih FW, et al. (2010) Cutting edge: granulocyte-macrophage colony-stimulating factor is the major CD8+ T cell-derived licensing factor for dendritic cell activation. J Immunol 184: 4625-4629.
-
(2010)
J Immunol
, vol.184
, pp. 4625-4629
-
-
Min, L.1
Mohammad Isa, S.A.2
Shuai, W.3
Piang, C.B.4
Nih, F.W.5
-
24
-
-
0033774855
-
Granulocyte-macrophage colony-stimulating factor regulates cytokine production in cultured macrophages through CD14-dependent and -independent mechanisms
-
Bergamini A, Bolacchi F, Bongiovanni B, Cepparulo M, Ventura L, et al. (2000) Granulocyte-macrophage colony-stimulating factor regulates cytokine production in cultured macrophages through CD14-dependent and-independent mechanisms. Immunology 101: 254-261.
-
(2000)
Immunology
, vol.101
, pp. 254-261
-
-
Bergamini, A.1
Bolacchi, F.2
Bongiovanni, B.3
Cepparulo, M.4
Ventura, L.5
-
25
-
-
14844360845
-
Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice
-
Osiecki K, Xie L, Zheng JH, Squires R, Pettoello-Mantovani M, et al. (2005) Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice. AIDS Res Hum Retroviruses 21: 125-139.
-
(2005)
AIDS Res Hum Retroviruses
, vol.21
, pp. 125-139
-
-
Osiecki, K.1
Xie, L.2
Zheng, J.H.3
Squires, R.4
Pettoello-Mantovani, M.5
-
26
-
-
0029889216
-
Transcriptional and post-transcriptional regulation of GM-CSF-induced IL-1 beta gene expression in PMN
-
Fernandez MC, Walters J, Marucha P, (1996) Transcriptional and post-transcriptional regulation of GM-CSF-induced IL-1 beta gene expression in PMN. Journal of leukocyte biology 59: 598-603.
-
(1996)
Journal of Leukocyte Biology
, vol.59
, pp. 598-603
-
-
Fernandez, M.C.1
Walters, J.2
Marucha, P.3
-
27
-
-
0025057045
-
Recombinant human granulocyte-macrophage colony-stimulating factor induces granule exocytosis from human polymorphonuclear neutrophils
-
Smith RJ, Justen JM, Sam LM, (1990) Recombinant human granulocyte-macrophage colony-stimulating factor induces granule exocytosis from human polymorphonuclear neutrophils. Inflammation 14: 83-92.
-
(1990)
Inflammation
, vol.14
, pp. 83-92
-
-
Smith, R.J.1
Justen, J.M.2
Sam, L.M.3
-
28
-
-
48449102092
-
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation
-
Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, et al. (2008) The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell 134: 496-507.
-
(2008)
Cell
, vol.134
, pp. 496-507
-
-
Hansen, G.1
Hercus, T.R.2
McClure, B.J.3
Stomski, F.C.4
Dottore, M.5
-
29
-
-
70349336496
-
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease
-
Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, et al. (2009) The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood 114: 1289-1298.
-
(2009)
Blood
, vol.114
, pp. 1289-1298
-
-
Hercus, T.R.1
Thomas, D.2
Guthridge, M.A.3
Ekert, P.G.4
King-Scott, J.5
-
30
-
-
0038644520
-
GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta
-
Ebner K, Bandion A, Binder BR, de Martin R, Schmid JA, (2003) GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta. Blood 102: 192-199.
-
(2003)
Blood
, vol.102
, pp. 192-199
-
-
Ebner, K.1
Bandion, A.2
Binder, B.R.3
de Martin, R.4
Schmid, J.A.5
-
31
-
-
0037155133
-
Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kappa B activation in murine proB cell line Ba/F3 cells
-
Nakamura T, Ouchida R, Kodama T, Kawashima T, Makino Y, et al. (2002) Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kappa B activation in murine proB cell line Ba/F3 cells. J Biol Chem 277: 6254-6265.
-
(2002)
J Biol Chem
, vol.277
, pp. 6254-6265
-
-
Nakamura, T.1
Ouchida, R.2
Kodama, T.3
Kawashima, T.4
Makino, Y.5
-
32
-
-
77956410301
-
A novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit
-
Meads MB, Li ZW, Dalton WS, (2010) A novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit. J Immunol 185: 1606-1615.
-
(2010)
J Immunol
, vol.185
, pp. 1606-1615
-
-
Meads, M.B.1
Li, Z.W.2
Dalton, W.S.3
-
33
-
-
77956137185
-
IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response
-
Rao P, Hayden MS, Long M, Scott ML, West AP, et al. (2010) IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response. Nature 466: 1115-1119.
-
(2010)
Nature
, vol.466
, pp. 1115-1119
-
-
Rao, P.1
Hayden, M.S.2
Long, M.3
Scott, M.L.4
West, A.P.5
-
34
-
-
78649421803
-
I{kappa}B{beta} is an essential co-activator for LPS-induced IL-1{beta} transcription in vivo
-
Scheibel M, Klein B, Merkle H, Schulz M, Fritsch R, et al. (2010) I{kappa}B{beta} is an essential co-activator for LPS-induced IL-1{beta} transcription in vivo. J Exp Med.
-
(2010)
J Exp Med
-
-
Scheibel, M.1
Klein, B.2
Merkle, H.3
Schulz, M.4
Fritsch, R.5
-
35
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, et al. (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267: 2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
-
36
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S, Miura M, Jung YK, Zhu H, Li E, et al. (1998) Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92: 501-509.
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
-
37
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, et al. (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430: 213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
-
38
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, et al. (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
-
39
-
-
0031201475
-
Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice
-
Basu S, Dunn AR, Marino MW, Savoia H, Hodgson G, et al. (1997) Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice. J Immunol 159: 1412-1417.
-
(1997)
J Immunol
, vol.159
, pp. 1412-1417
-
-
Basu, S.1
Dunn, A.R.2
Marino, M.W.3
Savoia, H.4
Hodgson, G.5
-
40
-
-
0028278043
-
Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice
-
Tiegs G, Barsig J, Matiba B, Uhlig S, Wendel A, (1994) Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice. J Clin Invest 93: 2616-2622.
-
(1994)
J Clin Invest
, vol.93
, pp. 2616-2622
-
-
Tiegs, G.1
Barsig, J.2
Matiba, B.3
Uhlig, S.4
Wendel, A.5
|