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Volumn 13, Issue 3, 2007, Pages 795-798

Nitric oxide and its gatekeeper thrombospondin-1 in tumor angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; BEVACIZUMAB; CD36 ANTIGEN; CD47 ANTIGEN; CISPLATIN; CYCLIC GMP; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; GUANYLATE CYCLASE; INTERLEUKIN 2; ION CHANNEL; ISOSORBIDE MONONITRATE; N ACETYLSARCOSYLGLYCYLVALYL DEXTRO ALLOISOLEUCYLTHREONYLNORVALYLISOLEUCYLARGINYLPROLINE ETHYLAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RANIBIZUMAB; THROMBOSPONDIN 1; VASCULOTROPIN;

EID: 33847414524     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-1758     Document Type: Review
Times cited : (59)

References (67)
  • 1
    • 33644532890 scopus 로고    scopus 로고
    • Tumor angiogenesis and therapy
    • Cao Y. Tumor angiogenesis and therapy. Biomed Pharmacother 2005;59:S340-3.
    • (2005) Biomed Pharmacother , vol.59
    • Cao, Y.1
  • 2
    • 33644842284 scopus 로고    scopus 로고
    • Molecular regulation of tumor angiogenesis: Mechanisms and therapeutic implications
    • Harper J, Moses MA. Molecular regulation of tumor angiogenesis: mechanisms and therapeutic implications. EXS 2006:223-68.
    • (2006) EXS , pp. 223-268
    • Harper, J.1    Moses, M.A.2
  • 3
    • 0033213978 scopus 로고    scopus 로고
    • Tumor development under angiogenic signaling: A dynamical theory of tumor growth, treatment response, and post-vascular dormancy
    • Hahnfeldt P, Panigrahy D, Folkman J, Hlatky L. Tumor development under angiogenic signaling: a dynamical theory of tumor growth, treatment response, and post-vascular dormancy. Cancer Res 1999;59:4770-5.
    • (1999) Cancer Res , vol.59 , pp. 4770-4775
    • Hahnfeldt, P.1    Panigrahy, D.2    Folkman, J.3    Hlatky, L.4
  • 4
    • 32944463899 scopus 로고    scopus 로고
    • Angiogenesis
    • Folkman J. Angiogenesis. Annu Rev Med 2006;57:1-18.
    • (2006) Annu Rev Med , vol.57 , pp. 1-18
    • Folkman, J.1
  • 5
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 2002;29:15-8.
    • (2002) Semin Oncol , vol.29 , pp. 15-18
    • Folkman, J.1
  • 6
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001;7:1194-201.
    • (2001) Nat Med , vol.7 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3    Costa, C.4    Blaikie, P.5    Butros, L.6
  • 7
    • 27544475061 scopus 로고    scopus 로고
    • Pericytes and endothelial precursor cells: Cellular interactions and contributions to malignancy
    • Bagley RG, Weber W, Rouleau C, Teicher BA. Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy. Cancer Res 2005;65:9741-50.
    • (2005) Cancer Res , vol.65 , pp. 9741-9750
    • Bagley, R.G.1    Weber, W.2    Rouleau, C.3    Teicher, B.A.4
  • 8
    • 0141731291 scopus 로고    scopus 로고
    • Endothelial precursor cells as a model of tumor endothelium: Characterization and comparison with mature endothelial cells
    • Bagley RG, Walter-Yohrling J, Cao X, et al. Endothelial precursor cells as a model of tumor endothelium: characterization and comparison with mature endothelial cells. Cancer Res 2003;63:5866-73.
    • (2003) Cancer Res , vol.63 , pp. 5866-5873
    • Bagley, R.G.1    Walter-Yohrling, J.2    Cao, X.3
  • 9
    • 0141988568 scopus 로고    scopus 로고
    • Fundamental concepts of the angiogenic process
    • Folkman J. Fundamental concepts of the angiogenic process. Curr Mol Med 2003;3:643-51.
    • (2003) Curr Mol Med , vol.3 , pp. 643-651
    • Folkman, J.1
  • 15
    • 0033588842 scopus 로고    scopus 로고
    • New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
    • Holash J, Wiegand SJ, Yancopoulos GD. New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 1999;18:5356-62.
    • (1999) Oncogene , vol.18 , pp. 5356-5362
    • Holash, J.1    Wiegand, S.J.2    Yancopoulos, G.D.3
  • 17
    • 0033061404 scopus 로고    scopus 로고
    • Pathophysiology of tumor angiogenesis and its relevance in renal cell cancer
    • Strohmeyer D. Pathophysiology of tumor angiogenesis and its relevance in renal cell cancer. Anticancer Res 1999;19:1557-61.
    • (1999) Anticancer Res , vol.19 , pp. 1557-1561
    • Strohmeyer, D.1
  • 18
    • 12744281248 scopus 로고    scopus 로고
    • Nitric oxide and the angiogenic response: Can we improve the results of therapeutic angiogenesis?
    • Kapila V, Sellke FW, Suuronen EJ, Mesana TG, Ruel M. Nitric oxide and the angiogenic response: can we improve the results of therapeutic angiogenesis? Expert Opin Investig Drugs 2005;14:37-44.
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 37-44
    • Kapila, V.1    Sellke, F.W.2    Suuronen, E.J.3    Mesana, T.G.4    Ruel, M.5
  • 19
    • 0036775702 scopus 로고    scopus 로고
    • Nitric oxide and angiogenesis in cardiovascular disease
    • Murohara T, Asahara T. Nitric oxide and angiogenesis in cardiovascular disease. Antioxid Redox Signal 2002;4:825-31.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 825-831
    • Murohara, T.1    Asahara, T.2
  • 20
    • 0037277578 scopus 로고    scopus 로고
    • Role of nitric oxide in the modulation of angiogenesis
    • Morbidelli L, Donnini S, Ziche M. Role of nitric oxide in the modulation of angiogenesis. Curr Pharm Des 2003;9:521-30.
    • (2003) Curr Pharm Des , vol.9 , pp. 521-530
    • Morbidelli, L.1    Donnini, S.2    Ziche, M.3
  • 23
    • 0035296203 scopus 로고    scopus 로고
    • Role of nitric oxide in carcinogenesis and tumour progression
    • Lala PK, Chakraborty C. Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol 2001;2:149-56.
    • (2001) Lancet Oncol , vol.2 , pp. 149-156
    • Lala, P.K.1    Chakraborty, C.2
  • 24
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial nitric oxide synthase: Why isn't calcium/calmodulin enough?
    • Fulton D, Gratton JP, Sessa WC. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 2001;299:818-24.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.P.2    Sessa, W.C.3
  • 25
    • 1642619061 scopus 로고    scopus 로고
    • Role of eNOS in neovascularization: NO for endothelial progenitor cells
    • Duda DG, Fukumura D, Jain RK. Role of eNOS in neovascularization: NO for endothelial progenitor cells. Trends Mol Med 2004;10:143-5.
    • (2004) Trends Mol Med , vol.10 , pp. 143-145
    • Duda, D.G.1    Fukumura, D.2    Jain, R.K.3
  • 28
    • 0030988217 scopus 로고    scopus 로고
    • Structure-function aspects in the nitric oxide synthases
    • Stuehr DJ. Structure-function aspects in the nitric oxide synthases. Annu Rev Pharmacol Toxicol 1997;37:339-59.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 339-359
    • Stuehr, D.J.1
  • 29
    • 0024537028 scopus 로고
    • Endothelium-derived nitric oxide: Actions and properties
    • Ignarro LJ. Endothelium-derived nitric oxide: actions and properties. FASEB J 1989;3:31-6.
    • (1989) FASEB J , vol.3 , pp. 31-36
    • Ignarro, L.J.1
  • 30
    • 0037422535 scopus 로고    scopus 로고
    • Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
    • Hofseth LJ, Saito S, Hussain SP, et al. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci U S A 2003;100:143-8.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 143-148
    • Hofseth, L.J.1    Saito, S.2    Hussain, S.P.3
  • 31
    • 0034646663 scopus 로고    scopus 로고
    • Nitrosative capacity of macrophages is dependent on nitric-oxide synthase induction signals
    • Espey MG, Miranda KM, Pluta RM, Wink DA. Nitrosative capacity of macrophages is dependent on nitric-oxide synthase induction signals. J Biol Chem 2000;275:11341-7.
    • (2000) J Biol Chem , vol.275 , pp. 11341-11347
    • Espey, M.G.1    Miranda, K.M.2    Pluta, R.M.3    Wink, D.A.4
  • 32
    • 0032031678 scopus 로고    scopus 로고
    • Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer
    • Yamasaki K, Edington HD, McClosky C, et al. Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest 1998;101:967-71.
    • (1998) J Clin Invest , vol.101 , pp. 967-971
    • Yamasaki, K.1    Edington, H.D.2    McClosky, C.3
  • 33
    • 0043234527 scopus 로고    scopus 로고
    • Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex
    • Takahashi S, Mendelsohn ME. Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex. J Biol Chem 2003;278:30821-7.
    • (2003) J Biol Chem , vol.278 , pp. 30821-30827
    • Takahashi, S.1    Mendelsohn, M.E.2
  • 34
    • 0942265997 scopus 로고    scopus 로고
    • HSP90 and Akt modulate Ang-1-induced angiogenesis via NO in coronary artery endothelium
    • Chen JX, Lawrence ML, Cunningham G, Christman BW, Meyrick B. HSP90 and Akt modulate Ang-1-induced angiogenesis via NO in coronary artery endothelium. J Appl Physiol 2004;96:612-20.
    • (2004) J Appl Physiol , vol.96 , pp. 612-620
    • Chen, J.X.1    Lawrence, M.L.2    Cunningham, G.3    Christman, B.W.4    Meyrick, B.5
  • 35
    • 0036969044 scopus 로고    scopus 로고
    • 17-beta-oestradiol- induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism
    • Bucci M, Roviezzo F, Cicala C, Pinto A, Cirino G. 17-beta-oestradiol- induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism. Br J Pharmacol 2002;135:1695-700.
    • (2002) Br J Pharmacol , vol.135 , pp. 1695-1700
    • Bucci, M.1    Roviezzo, F.2    Cicala, C.3    Pinto, A.4    Cirino, G.5
  • 37
    • 0037013152 scopus 로고    scopus 로고
    • Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release
    • Fontana J, Fulton D, Chen Y, et al. Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res 2002;90:866-73.
    • (2002) Circ Res , vol.90 , pp. 866-873
    • Fontana, J.1    Fulton, D.2    Chen, Y.3
  • 38
    • 27644584796 scopus 로고    scopus 로고
    • Update on angiogenesis inhibitors
    • Zakarija A, Soff G. Update on angiogenesis inhibitors. Curr Opin Oncol 2005;17:578-83.
    • (2005) Curr Opin Oncol , vol.17 , pp. 578-583
    • Zakarija, A.1    Soff, G.2
  • 39
    • 0036584733 scopus 로고    scopus 로고
    • Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin
    • Urbich C, Reissner A, Chavakis E, et al. Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin. FASEB J 2002;16:706-8.
    • (2002) FASEB J , vol.16 , pp. 706-708
    • Urbich, C.1    Reissner, A.2    Chavakis, E.3
  • 40
    • 33645470397 scopus 로고    scopus 로고
    • Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis
    • Sanderson S, Valenti M, Gowan S, et al. Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis. Mol Cancer Ther 2006;5:522-32.
    • (2006) Mol Cancer Ther , vol.5 , pp. 522-532
    • Sanderson, S.1    Valenti, M.2    Gowan, S.3
  • 41
    • 0037067712 scopus 로고    scopus 로고
    • Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase
    • Dikalov S, Landmesser U, Harrison DG. Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase. J Biol Chem 2002;277:25480-5.
    • (2002) J Biol Chem , vol.277 , pp. 25480-25485
    • Dikalov, S.1    Landmesser, U.2    Harrison, D.G.3
  • 42
    • 0029797025 scopus 로고    scopus 로고
    • Regulation of tumor growth and metastasis by thrombospondin-1
    • Roberts DD. Regulation of tumor growth and metastasis by thrombospondin-1. FASEB J 1996;10:1183-91.
    • (1996) FASEB J , vol.10 , pp. 1183-1191
    • Roberts, D.D.1
  • 43
    • 0036362236 scopus 로고    scopus 로고
    • Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
    • Lawler J. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med 2002;6:1-12.
    • (2002) J Cell Mol Med , vol.6 , pp. 1-12
    • Lawler, J.1
  • 44
    • 4444353257 scopus 로고    scopus 로고
    • Tumor progression: The effects of thrombospondin-1 and -2
    • Lawler J, Detmar M. Tumor progression: the effects of thrombospondin-1 and -2. Int J Biochem Cell Biol 2004;36:1038-45.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1038-1045
    • Lawler, J.1    Detmar, M.2
  • 45
    • 0033734494 scopus 로고    scopus 로고
    • The cell biology of thrombospondin-1
    • Chen H, Herndon ME, Lawler J. The cell biology of thrombospondin-1. Matrix Biol 2000;19:597-614.
    • (2000) Matrix Biol , vol.19 , pp. 597-614
    • Chen, H.1    Herndon, M.E.2    Lawler, J.3
  • 46
    • 14744294395 scopus 로고    scopus 로고
    • Novel integrin antagonists derived from thrombospondins
    • Calzada MJ, Roberts DD. Novel integrin antagonists derived from thrombospondins. Curr Pharm Des 2005;11:849-66.
    • (2005) Curr Pharm Des , vol.11 , pp. 849-866
    • Calzada, M.J.1    Roberts, D.D.2
  • 48
    • 33751582239 scopus 로고    scopus 로고
    • Thrombospondin-1 antagonises nitric oxide stimulated vascular smooth muscle cell responses
    • Isenberg JS, Wink DA, Roberts DD. Thrombospondin-1 antagonises nitric oxide stimulated vascular smooth muscle cell responses. Cardiovasc Res 2006;71:785-93.
    • (2006) Cardiovasc Res , vol.71 , pp. 785-793
    • Isenberg, J.S.1    Wink, D.A.2    Roberts, D.D.3
  • 49
    • 33748747969 scopus 로고    scopus 로고
    • CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1
    • Isenberg JS, Ridnour LA, Dimitry J, Frazier WA, Wink DA, Roberts DD. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem 2006;281:26069-80.
    • (2006) J Biol Chem , vol.281 , pp. 26069-26080
    • Isenberg, J.S.1    Ridnour, L.A.2    Dimitry, J.3    Frazier, W.A.4    Wink, D.A.5    Roberts, D.D.6
  • 50
    • 33645096502 scopus 로고    scopus 로고
    • ABT-510: Oncolytic Angiogenesis Inhibitor
    • Sorbera L, Bayes M. ABT-510: oncolytic Angiogenesis Inhibitor. Drugs of the Future 2005;30:1081-6.
    • (2005) Drugs of the Future , vol.30 , pp. 1081-1086
    • Sorbera, L.1    Bayes, M.2
  • 51
    • 33646525162 scopus 로고    scopus 로고
    • Effect of acute inhibition of nitric oxide synthesis by I-NAME on cardiovascular responses following peripheral autonomic blockade in rabbits
    • Eldesoky ES. Effect of acute inhibition of nitric oxide synthesis by I-NAME on cardiovascular responses following peripheral autonomic blockade in rabbits. Pharmacol 2006;20:239-45.
    • (2006) Pharmacol , vol.20 , pp. 239-245
    • Eldesoky, E.S.1
  • 53
    • 32944469353 scopus 로고    scopus 로고
    • Pegylated arginine deiminase treatment of patients with metastatic melanoma: Results from phase I and II studies
    • Ascierto PA, Scala S, Castello G, et al. Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies. J Clin Oncol 2005;23:7660-8.
    • (2005) J Clin Oncol , vol.23 , pp. 7660-7668
    • Ascierto, P.A.1    Scala, S.2    Castello, G.3
  • 54
    • 3042744030 scopus 로고    scopus 로고
    • Pegylated arginine deiminase treatment of patients with unresect-able hepatocellular carcinoma: Results from phase I/II studies
    • Izzo F, Marra P, Beneduce G, et al. Pegylated arginine deiminase treatment of patients with unresect-able hepatocellular carcinoma: results from phase I/II studies. J Clin Oncol 2004;22:1815-22.
    • (2004) J Clin Oncol , vol.22 , pp. 1815-1822
    • Izzo, F.1    Marra, P.2    Beneduce, G.3
  • 55
    • 19344365089 scopus 로고    scopus 로고
    • Remission of hepatocellular carcinoma with arginine depletion induced by systemic release of endogenous hepatic arginase due to transhepatic arterial embolisation, augmented by high-dose insulin: Arginase as a potential drug candidate for hepatocellular carcinoma
    • Cheng PN, Leung YC, Lo WH, Tsui SM, Lam KC. Remission of hepatocellular carcinoma with arginine depletion induced by systemic release of endogenous hepatic arginase due to transhepatic arterial embolisation, augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma Cancer Lett 2005;224:67-80.
    • (2005) Cancer Lett , vol.224 , pp. 67-80
    • Cheng, P.N.1    Leung, Y.C.2    Lo, W.H.3    Tsui, S.M.4    Lam, K.C.5
  • 56
    • 0028989755 scopus 로고
    • G-methyl- L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension
    • G-methyl- L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension. Crit Care Med 1995;23:1018-24.
    • (1995) Crit Care Med , vol.23 , pp. 1018-1024
    • Kilbourn, R.G.1    Fonseca, G.A.2    Griffith, O.W.3
  • 57
    • 4444356585 scopus 로고    scopus 로고
    • Does administration of isosorbide mononitrate affect cellular proliferation in oral squamous cell carcinoma? A prospective randomized clinical study
    • Downie IP, Umar T, Boote DJ, Mellor TK, Hoffman GR, Brennan PA. Does administration of isosorbide mononitrate affect cellular proliferation in oral squamous cell carcinoma? A prospective randomized clinical study. J Oral Maxillofac Surg 2004;62:1064-8.
    • (2004) J Oral Maxillofac Surg , vol.62 , pp. 1064-1068
    • Downie, I.P.1    Umar, T.2    Boote, D.J.3    Mellor, T.K.4    Hoffman, G.R.5    Brennan, P.A.6
  • 59
    • 33746061276 scopus 로고    scopus 로고
    • Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: Effects on molecular targets
    • Rao CV, Reddy BS, Steele VE, et al. Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets. Mol Cancer Ther 2006;5:1530-8.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1530-1538
    • Rao, C.V.1    Reddy, B.S.2    Steele, V.E.3
  • 60
    • 1642368865 scopus 로고    scopus 로고
    • Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression
    • Hamano Y, Sugimoto H, Soubasakos MA, et al. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res 2004;64:1570-4.
    • (2004) Cancer Res , vol.64 , pp. 1570-1574
    • Hamano, Y.1    Sugimoto, H.2    Soubasakos, M.A.3
  • 61
    • 20944443196 scopus 로고    scopus 로고
    • Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities
    • Haviv F, Bradley MF, Kalvin DM, et al. Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 2005;48:2838-46.
    • (2005) J Med Chem , vol.48 , pp. 2838-2846
    • Haviv, F.1    Bradley, M.F.2    Kalvin, D.M.3
  • 62
    • 24644508961 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer
    • Hoekstra R, de Vos FY, Eskens FA, et al. Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer. J Clin Oncol 2005;23:5188-97.
    • (2005) J Clin Oncol , vol.23 , pp. 5188-5197
    • Hoekstra, R.1    de Vos, F.Y.2    Eskens, F.A.3
  • 63
    • 25144488561 scopus 로고    scopus 로고
    • Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy
    • Yap R, Veliceasa D, Emmenegger U, et al. Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: a complementation antiangiogenic strategy. Clin Cancer Res 2005;11:6678-85.
    • (2005) Clin Cancer Res , vol.11 , pp. 6678-6685
    • Yap, R.1    Veliceasa, D.2    Emmenegger, U.3
  • 64
    • 32444431721 scopus 로고    scopus 로고
    • Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combination
    • Hoekstra R, de Vos FY, Eskens FA, et al. Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: a safe combination. Eur J Cancer 2006;42:467-72.
    • (2006) Eur J Cancer , vol.42 , pp. 467-472
    • Hoekstra, R.1    de Vos, F.Y.2    Eskens, F.A.3
  • 65
    • 33747883001 scopus 로고    scopus 로고
    • A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors
    • Gietema JA, Hoekstra R, de Vos FY, et al. A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors. Ann Oncol 2006;17:1320-7.
    • (2006) Ann Oncol , vol.17 , pp. 1320-1327
    • Gietema, J.A.1    Hoekstra, R.2    de Vos, F.Y.3
  • 66
    • 0942268140 scopus 로고    scopus 로고
    • Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts
    • Rofstad EK, Galappathi K, Mathiesen B. Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts. Int J Radiat Oncol Biol Phys 2004;58:493-9.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 493-499
    • Rofstad, E.K.1    Galappathi, K.2    Mathiesen, B.3
  • 67
    • 0041672462 scopus 로고    scopus 로고
    • Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts
    • Rofstad EK, Henriksen K, Galappathi K, Mathiesen B. Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts. Cancer Res 2003;63:4055-61.
    • (2003) Cancer Res , vol.63 , pp. 4055-4061
    • Rofstad, E.K.1    Henriksen, K.2    Galappathi, K.3    Mathiesen, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.